Moderna, Inc. · MRNA · FY2025 Q2 · Calendar Q3 2025

Moderna balances portfolio progress with lower revenue guidance

The quarter supports a mixed view: portfolio expansion, flu efficacy data and cost discipline strengthen the longer-term pipeline and operating outlook, while lower guidance, seasonal COVID demand and regulatory dependence limit near-term visibility.

Reported Before market openNASDAQHealthcare $74.38B market cap
90quality score

Earnings scorecard

Reported versus consensus
Reported EPS $-2.13 Consensus $-2.99
EPS surprise +28.8% Reported versus consensus
Reported revenue $142.0M Consensus $893.3M
Revenue surprise -84.1% Reported versus consensus

Market reaction

prior-close to event-session close
Stock move -6.6% Event window
SPY move -1.6% Same window
Abnormal move -5.0% Stock minus SPY
Volume 1.9× Versus trailing sessions
Subsequent drift -12.7% Up to 20 sessions
MRNASPY benchmark

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What changed

Moderna added three FDA approvals, reported positive Phase III flu efficacy data and emphasized further cost reductions. The company also lowered the high end of 2025 revenue guidance because of a U.K. shipment-timing shift, while continuing to advance CMV, norovirus, oncology and rare-disease programs.

Guidance delta

2025 revenue guidance was lowered at the high end to $2.2 billion, reflecting a U.K. COVID shipment-timing shift.

Key takeaways

  • Three FDA approvals broadened Moderna's commercial portfolio.
  • Phase III flu data showed 26.6% higher efficacy versus standard dose.
  • Management highlighted cost reductions, pipeline progress and international commercial expansion.
  • The key offset was lower high-end 2025 revenue guidance tied to U.K. shipment timing.

Management priorities

  • Advance flu, flu-COVID combination, CMV and norovirus programs toward regulatory milestones
  • Advance intismeran studies in melanoma and metastatic disease
  • Reduce operating expenses toward the $4.2 billion cash-cost target by 2027
  • Expand AI tools across product planning and research

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Earnings History

Estimate Beat Miss Match
MRNA EPS earnings history estimate and actual scatter chart 9 reported fiscal quarters and 3 future estimate-only quarters. Q1 '24 estimate $-3.56 Q1 '24 actual $-3.07, beat Q2 '24 estimate $-3.35 Q2 '24 actual $-3.33, beat Q3 '24 estimate $-1.90 Q3 '24 actual $0.03, beat Q2 '25 estimate $-2.99 Q2 '25 actual $-2.13, beat Q3 '25 estimate $-1.87 Q3 '25 actual $-0.51, beat Q4 '25 estimate $-2.54 Q4 '25 actual $-2.11, beat Q1 '26 estimate $-4.45 Q1 '26 actual $-3.40, beat Q2 '26 estimate $-2.03 Q2 '26 actual $-1.97, beat Q3 '26 estimate $-1.10 Q4 '26 estimate $-1.96 Q1 '27 estimate $-1.81
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Analyst Consensus ?

ConsensusHold29 ratings
Bullish827.6%
Neutral1551.7%
Bearish620.7%

Analyst 52W Price Targets

$196.48Current
$15Low
$115.12Average
$350High

Latest persisted target per named analyst; persisted current price from FN2's market snapshot as of Oct 7, 2026. Not an FN2 forecast.

Firm-level rating actions

FMP grade actions identify the grading firm, not a named analyst.

FirmRatingPrior ratingActionDate
Citigroup Sell NeutralDowngradeSep 30, 2026
Rothschild & Co Sell NeutralDowngradeSep 3, 2026
Argus Research Buy HoldUpgradeAug 28, 2026
Wolfe Research Peer Perform UnderperformUpgradeAug 25, 2026
Barclays Equal Weight Equal WeightMaintainAug 24, 2026
Show 24 more rating actions

Named analyst price targets

Upside is calculated against the persisted current price $196.48. FMP does not supply a rating on these named-analyst rows.

FirmAnalyst52W targetPrice when postedUpsideDate
UBSAnalyst unavailable$81$150.81 -58.8%Sep 3, 2026
Argus ResearchJohn Eade$180$142.77 -8.4%Aug 28, 2026
BarclaysEliana Merle$125$145.13 -36.4%Aug 24, 2026
UBSMichael Yee$150$174.38 -23.7%Aug 20, 2026
Goldman SachsAnalyst unavailable$120$174.38 -38.9%Aug 19, 2026
See 85 more

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Company context

Snapshot as of publication

Moderna, Inc., a biotechnology firm, is dedicated to the discovery, development, and commercialization of messenger RNA (mRNA) based therapies and preventive medicines. Its extensive research and development efforts target a broad spectrum of medical needs, including infectious diseases, cancer immunology, rare conditions, cardiovascular ailments, and autoimmune disorders, with operations spanning the United States, Europe, and other global markets. The company's diverse product pipeline encompasses various vaccine candidates: those for respiratory illnesses like COVID-19, influenza, and respiratory syncytial virus (RSV); latent viral infections such as cytomegalovirus (CMV), Epstein-Barr virus (EBV), human immunodeficiency virus (HIV), herpes simplex virus (HSV), and varicella-zoster virus (VZV); and public health threats like Zika and Nipah.…

Historical context

All MRNA earnings

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Latest beats and misses

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Sources

  1. Earnings call transcript and parsed analysis · 2026-05-11T10:29:34.698584+00:00
  2. FN2 earnings calendar · 2026-07-26T00:37:12.209961+00:00
  3. Polygon adjusted daily market bars · 2026-10-07T20:10:45.829433+00:00
  4. Financial Modeling Prep analyst price-target consensus and quote snapshot · 2026-10-07T20:10:45.826706+00:00

Methodology

Reported and consensus figures come from FN2's earnings event records. Market reaction and volume are calculated from daily adjusted bars around the event; abnormal move subtracts the SPY move over the same window.

Analyst target low, average, and high values are derived at request time from each named analyst's latest persisted FMP target. The current-price marker comes from FN2's persisted market snapshot. They are sell-side estimates, not an FN2 valuation or recommendation.

Transcript intelligence is a structured synthesis of the current and prior earnings-call analyses. Missing values stay missing and are never estimated.

By FN2 Research · Updated · As of 2026-10-07. For educational purposes only; not investment advice.