Repligen Corporation · RGEN · FY2025 Q4 · Calendar Q1 2026

Repligen beat Q4 estimates; growth and execution remain in focus

The supplied analysis supports a constructive view of Repligen’s operating trajectory: FY2025 growth exceeded guidance, the quarter beat revenue and EPS estimates, and management maintained a growth outlook with a margin-expansion target. The thesis remains conditional on converting its opportunity funnel into orders and managing gene-therapy, tariff and macro headwinds.

Reported Before market openNASDAQHealthcare $11.23B market cap
100quality score

Earnings scorecard

Reported versus consensus
Reported EPS $0.49 Consensus $0.44
EPS surprise +11.4% Reported versus consensus
Reported revenue $197.9M Consensus $192.9M
Revenue surprise +2.6% Reported versus consensus

Market reaction

prior-close to event-session close
Stock move -0.5% Event window
SPY move +0.7% Same window
Abnormal move -1.3% Stock minus SPY
Volume 2.9× Versus trailing sessions
Subsequent drift -13.6% Up to 20 sessions
RGENSPY benchmark

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Transcript intelligence

What changed

The FY2025 Q4 analysis describes continued broad-based growth and margin progress after the prior quarter’s strong results. Management’s 2026 outlook is maintained rather than newly raised; the analysis also highlights a gene-therapy headwind to Filtration and continued uncertainty around tariffs and customer capital spending.

Guidance delta

Management maintained 2026 revenue guidance of $810–$840 million and organic growth guidance of 9–13%, with a 150-basis-point operating-margin expansion target. The supplied analysis does not report a change to these 2026 targets from the prior call.

Key takeaways

  • FY2025 revenue and organic growth exceeded guidance, according to the supplied transcript analysis.
  • The quarter’s reported EPS and revenue exceeded consensus estimates.
  • Management cited strength across proteins, analytics, chromatography and filtration, alongside product launches and service-attachment opportunities.
  • The 2026 outlook calls for continued growth and operating-margin expansion, while guidance sentiment is maintained.
  • The analysis identifies a three-point organic headwind to Filtration from a gene-therapy platform.

Management priorities

  • Launch additional catalog resins and custom resin projects.
  • Develop ATF-MAVERICK Raman integration and Mid-IR technology.
  • Expand services attachment and cross-selling to strategic accounts.
  • Continue M&A focused on differentiated bioprocess technologies.
  • Advance IT modernization, AI investment and Fit-for-Growth initiatives.

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Earnings History

Estimate Beat Miss Match
RGEN EPS earnings history estimate and actual scatter chart 9 reported fiscal quarters and 4 future estimate-only quarters. Q1 '24 estimate $0.29 Q1 '24 actual $0.28, match Q2 '24 estimate $0.33 Q2 '24 actual $0.33, match Q2 '25 estimate $0.40 Q2 '25 actual $0.37, miss Q3 '25 estimate $0.42 Q3 '25 actual $0.46, beat Q4 '25 estimate $0.44 Q4 '25 actual $0.49, beat Q1 '26 estimate $0.38 Q1 '26 actual $0.48, beat Q2 '26 estimate $0.45 Q2 '26 actual $0.54, beat Q3 '26 estimate $0.46 Q3 '26 actual $0.53, beat Q4 '26 estimate $0.52 Q1 '27 estimate $0.59 Q2 '27 estimate $0.65 Q3 '27 estimate $0.67
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Analyst Consensus ?

ConsensusBuy23 ratings
Bullish2191.3%
Neutral28.7%
Bearish00.0%

Analyst 52W Price Targets

$176.94Current
$142Low
$188Average
$225High

Latest persisted target per named analyst; persisted current price from FN2's market snapshot as of Nov 1, 2026. Not an FN2 forecast.

Firm-level rating actions

FMP grade actions identify the grading firm, not a named analyst.

FirmRatingPrior ratingActionDate
RBC Capital Outperform OutperformMaintainOct 28, 2026
Canaccord Genuity Hold HoldMaintainOct 19, 2026
Barclays Overweight OverweightMaintainOct 7, 2026
UBS Buy BuyMaintainSep 9, 2026
Wells Fargo Overweight OverweightMaintainJul 30, 2026
Show 18 more rating actions

Named analyst price targets

Upside is calculated against the persisted current price $176.94. FMP does not supply a rating on these named-analyst rows.

FirmAnalyst52W targetPrice when postedUpsideDate
RBC CapitalDan Leonard$200$183.44 +13.0%Oct 28, 2026
Canaccord GenuityAnalyst unavailable$180$175.42 +1.7%Oct 19, 2026
BarclaysLuke Sergott$225$174.86 +27.2%Oct 7, 2026
UBSAnalyst unavailable$225$168.53 +27.2%Sep 9, 2026
Evercore ISIAnalyst unavailable$160$139.37 -9.6%Jul 6, 2026
See 22 more

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Company context

Snapshot as of publication

Repligen Corporation specializes in the creation and distribution of advanced bioprocessing technologies and integrated systems. These solutions are vital for various stages of biological drug production, serving clients across North America, Europe, the Asia Pacific region, and other international markets. The company's diverse product portfolio includes crucial components for biomanufacturing. This encompasses Protein A ligands, which serve as the key binding elements within Protein A affinity chromatography resins, as well as specialized cell culture growth factors. In the realm of chromatography, Repligen offers a range of products: Its OPUS line features pre-packed chromatography columns, instrumental in purifying biologics, alongside smaller-scale OPUS columns designed for high-throughput process development screening, viral clearance validation studies, and the scaling-down of chromatography processes. Additionally, the company supplies ELISA test kits and chromatography resins marketed under the CaptivA brand.…

Historical context

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Healthcare peers this season

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Latest beats and misses

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Sources

  1. Earnings call transcript and parsed analysis · 2026-05-11T10:29:34.698584+00:00
  2. FN2 earnings calendar · 2026-07-26T00:37:12.209961+00:00
  3. Polygon adjusted daily market bars · 2026-11-01T21:10:47.102514+00:00
  4. Financial Modeling Prep analyst price-target consensus and quote snapshot · 2026-11-01T21:10:47.099670+00:00

Methodology

Reported and consensus figures come from FN2's earnings event records. Market reaction and volume are calculated from daily adjusted bars around the event; abnormal move subtracts the SPY move over the same window.

Analyst target low, average, and high values are derived at request time from each named analyst's latest persisted FMP target. The current-price marker comes from FN2's persisted market snapshot. They are sell-side estimates, not an FN2 valuation or recommendation.

Transcript intelligence is a structured synthesis of the current and prior earnings-call analyses. Missing values stay missing and are never estimated.

By FN2 Research · Updated · As of 2026-11-01. For educational purposes only; not investment advice.