Pfizer Inc. · PFE · FY2025 Q2 · Calendar Q3 2025

Pfizer raises EPS outlook as pipeline and margins strengthen

The current analysis supports a constructive view of Pfizer's near-term earnings trajectory: management reported growth and margin progress, raised EPS guidance, and highlighted pipeline catalysts. The thesis is tempered by policy uncertainty, vaccine-demand volatility, competition, and execution risk.

Reported Before market openNYSEHealthcare $159.58B market cap
100quality score

Earnings scorecard

Reported versus consensus
Reported EPS $0.78 Consensus $0.58
EPS surprise +34.5% Reported versus consensus
Reported revenue $14.65B Consensus $13.56B
Revenue surprise +8.1% Reported versus consensus

Market reaction

prior-close to event-session close
Stock move +5.2% Event window
SPY move -0.5% Same window
Abnormal move +5.7% Stock minus SPY
Volume 2.7× Versus trailing sessions
Subsequent drift +0.2% Up to 20 sessions
PFESPY benchmark

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Transcript intelligence

What changed

Compared with the prior analysis, management moved from maintained to raised guidance, with stronger reported growth, continued margin expansion, and additional detail on pipeline progress and efficiency programs.

Guidance delta

Raised: full-year 2025 adjusted diluted EPS guidance increased by $0.10 to $2.90-$3.10 per share.

Key takeaways

  • Management described Q2 revenue growth, margin expansion, and operational efficiency gains.
  • Pipeline progress includes Elrexfio, SV, Hympavzi, and vaccine programs.
  • Policy uncertainty and pressure on established products remain important risks.

Management priorities

  • Advance oncology, cardiometabolic, and vaccine pipeline programs.
  • Improve margins through AI, manufacturing optimization, and cost initiatives.
  • Execute commercially while preserving capacity for targeted smaller acquisitions.

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Earnings History

Estimate Beat Miss Match
PFE REVENUE earnings history estimate and actual scatter chart 9 reported fiscal quarters and 3 future estimate-only quarters. Q1 '24 estimate $14B Q1 '24 actual $15B, beat Q2 '24 estimate $13B Q2 '24 actual $13B, beat Q3 '24 estimate $15B Q3 '24 actual $18B, beat Q2 '25 estimate $14B Q2 '25 actual $15B, beat Q3 '25 estimate $16B Q3 '25 actual $17B, beat Q4 '25 estimate $17B Q4 '25 actual $18B, beat Q1 '26 estimate $14B Q1 '26 actual $14B, beat Q2 '26 estimate $14B Q2 '26 actual $15B, beat Q3 '26 estimate $16B Q4 '26 estimate $17B Q1 '27 estimate $14B
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Analyst Consensus ?

ConsensusHold39 ratings
Bullish1538.4%
Neutral2359.0%
Bearish12.6%

1 unmapped firm rating excluded from the percentages.

Analyst 52W Price Targets

$28.28Current
$20Low
$39.14Average
$70High

Latest persisted target per named analyst; persisted current price from FN2's market snapshot as of Oct 9, 2026. Not an FN2 forecast.

Firm-level rating actions

FMP grade actions identify the grading firm, not a named analyst.

FirmRatingPrior ratingActionDate
Cantor Fitzgerald Neutral NeutralMaintainOct 8, 2026
Scotiabank Sector Outperform Sector OutperformMaintainOct 6, 2026
HSBC Hold HoldMaintainSep 10, 2026
Guggenheim Buy BuyMaintainAug 7, 2026
BMO Capital Outperform OutperformMaintainJul 13, 2026
Show 35 more rating actions

Named analyst price targets

Upside is calculated against the persisted current price $28.28. FMP does not supply a rating on these named-analyst rows.

FirmAnalyst52W targetPrice when postedUpsideDate
Cantor FitzgeraldCarter Gould$28$28 -1.0%Oct 8, 2026
ScotiabankAnalyst unavailable$33$27.3 +16.7%Oct 6, 2026
HSBCAnalyst unavailable$30$27.78 +6.1%Sep 10, 2026
GuggenheimAnalyst unavailable$31$26.2 +9.6%Aug 7, 2026
HSBCAnalyst unavailable$28$24.32 -1.0%Jul 6, 2026
See 59 more

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Company context

Snapshot as of publication

Pfizer Inc. is a global biopharmaceutical leader engaged in the research, development, production, marketing, and distribution of a wide array of medicinal and vaccine products worldwide. Its comprehensive portfolio addresses diverse therapeutic areas, including cardiovascular health and women's health, featuring key brands such as the Premarin family and Eliquis. The company also offers advanced biologics, small molecule drugs, immunotherapies, and biosimilars for various conditions, exemplified by Ibrance, Xtandi, and Retacrit. Furthermore, Pfizer provides sterile injectables, anti-infective agents, and a significant oral treatment for COVID-19, including Paxlovid.…

Historical context

All PFE earnings

Healthcare peers this season

Latest reports in the same sector
CompanyQuarterEPS surpriseMarket moveHeadline
COO The Cooper Companies, Inc. FY2026 Q3 · Calendar Q3 2026 +2.7% -14.7% CooperCompanies beats expectations as inventory reduction weighs on vision revenue
MDT Medtronic plc FY2027 Q1 · Calendar Q3 2026 +4.3% +1.5% Medtronic raises FY27 outlook as growth broadens across platforms

Latest beats and misses

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Sources

  1. Earnings call transcript and parsed analysis · 2026-05-11T10:29:34.698584+00:00
  2. FN2 earnings calendar · 2026-07-26T00:37:12.209961+00:00
  3. Polygon adjusted daily market bars · 2026-10-09T19:40:39.620556+00:00
  4. Financial Modeling Prep analyst price-target consensus and quote snapshot · 2026-10-09T19:40:39.617814+00:00

Methodology

Reported and consensus figures come from FN2's earnings event records. Market reaction and volume are calculated from daily adjusted bars around the event; abnormal move subtracts the SPY move over the same window.

Analyst target low, average, and high values are derived at request time from each named analyst's latest persisted FMP target. The current-price marker comes from FN2's persisted market snapshot. They are sell-side estimates, not an FN2 valuation or recommendation.

Transcript intelligence is a structured synthesis of the current and prior earnings-call analyses. Missing values stay missing and are never estimated.

By FN2 Research · Updated · As of 2026-10-09. For educational purposes only; not investment advice.