Pfizer Inc. · PFE · FY2026 Q1 · Calendar Q2 2026

Pfizer Q1 2026: Revenue and EPS Beat, Guidance Reaffirmed, Pipeline Advances

Pfizer's Q1 2026 results show the post-COVID turnaround continuing to build momentum. Revenue of $14.5B and adjusted EPS of $0.75 both exceeded consensus, driven by 22% operational growth in the launched and acquired portfolio led by Padcev, Nurtec, Eliquis, and Vyndamax. Legal settlements extending Vyndamax exclusivity to mid-2029 and a Belgian court ruling on Comirnaty improve cash-flow visibility and support a high-single-digit CAGR starting 2029. Management reaffirmed full-year guidance and highlighted roughly 20 pivotal study starts, 8 key readouts, and 4 regulatory decisions planned for 2026. Despite the beat, the stock saw a modest negative abnormal return on report day and has drifted approximately 4.2% lower subsequently, suggesting the market remains cautious about LOE pressures through 2028 and the 2028 timeline for the first obesity approval.

Reported Before market openNYSEHealthcare $140.61B market cap
100quality score

Company context

Snapshot as of publication

Pfizer Inc. is a global biopharmaceutical leader engaged in the research, development, production, marketing, and distribution of a wide array of medicinal and vaccine products worldwide. Its comprehensive portfolio addresses diverse therapeutic areas, including cardiovascular health and women's health, featuring key brands such as the Premarin family and Eliquis. The company also offers advanced biologics, small molecule drugs, immunotherapies, and biosimilars for various conditions, exemplified by Ibrance, Xtandi, and Retacrit. Furthermore, Pfizer provides sterile injectables, anti-infective agents, and a significant oral treatment for COVID-19, including Paxlovid.…

Earnings scorecard

Reported versus consensus
Reported EPS $0.75 Consensus $1
EPS surprise +3.9% Reported versus consensus
Reported revenue $14.45B Consensus $13.84B
Revenue surprise +4.4% Reported versus consensus

Earnings History

Estimate Beat Miss Match
PFE EPS earnings history estimate and actual scatter chart 8 reported fiscal quarters and 4 future estimate-only quarters. Q4 '23 estimate $-0.19 Q4 '23 actual $0.10, beat Q1 '24 estimate $0.52 Q1 '24 actual $0.82, beat Q2 '24 estimate $0.46 Q2 '24 actual $0.60, beat Q3 '24 estimate $0.61 Q3 '24 actual $1.06, beat Q2 '25 estimate $0.58 Q2 '25 actual $0.78, beat Q3 '25 estimate $0.63 Q3 '25 actual $0.87, beat Q4 '25 estimate $0.57 Q4 '25 actual $0.66, beat Q1 '26 estimate $0.72 Q1 '26 actual $0.75, beat Q2 '26 estimate $0.68 Q3 '26 estimate $0.82 Q4 '26 estimate $0.70 Q1 '27 estimate $0.66

Analyst Consensus ?

ConsensusHold38 ratings
Bullish1436.9%
Neutral2360.5%
Bearish12.6%

1 unmapped firm rating excluded from the percentages.

Analyst 52W Price Targets

$25.25Current
$20Low
$39.24Average
$70High

Latest persisted target per named analyst; persisted current price from FN2's market snapshot as of Jul 28, 2026. Not an FN2 forecast.

Firm-level rating actions

FMP grade actions identify the grading firm, not a named analyst.

FirmRatingPrior ratingActionDate
Guggenheim Buy BuyMaintainJul 13, 2026
BMO Capital Outperform OutperformMaintainJul 13, 2026
B of A Securities Neutral NeutralMaintainJul 10, 2026
JP Morgan Neutral NeutralMaintainJul 8, 2026
HSBC Hold BuyDowngradeJul 6, 2026
Cantor Fitzgerald Neutral NeutralMaintainJul 6, 2026
RBC Capital Sector Perform UnderperformUpgradeJun 10, 2026
Citigroup Neutral NeutralMaintainApr 29, 2026
Show 31 more rating actions

Named analyst price targets

Upside is calculated against the persisted current price $25.25. FMP does not supply a rating on these named-analyst rows.

FirmAnalyst52W targetPrice when postedUpsideDate
HSBCAnalyst unavailable$28$24.32 +10.9%Jul 6, 2026
UBSMichael Yee$27$26.34 +6.9%May 27, 2026
Wolfe ResearchAlexandria Hammond$26$25.96 +3.0%May 14, 2026
Morgan StanleyTerence Flynn$27$27.06 +6.9%Mar 17, 2026
BMO CapitalEvan David Seigerman$30$26.48 +18.8%Mar 9, 2026
RBC CapitalTrung Huynh$25$27.14 -1.0%Feb 24, 2026
BarclaysEmily Field$25$26.86 -1.0%Feb 19, 2026
DaiwaNarumi Nakagiri$27$27.73 +6.9%Feb 12, 2026
Cantor FitzgeraldAnalyst unavailable$27$25.88 +6.9%Jan 27, 2026
UBSAnalyst unavailable$25$25.43 -1.0%Jan 6, 2026
See 50 more

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Market reaction

prior-close to event-session close
Stock move +0.6% Event window
SPY move +0.8% Same window
Abnormal move -0.2% Stock minus SPY
Volume 1.7× Versus trailing sessions
Subsequent drift -4.2% Up to 20 sessions
PFESPY benchmark

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Transcript intelligence

What changed

Revenue of $14.5B beat the $13.84B estimate by 4.4%; adjusted EPS of $0.75 beat the $0.722 estimate by 3.9%. The launched and acquired portfolio contributed $3.1B, growing 22% operationally. A Vyndamax patent settlement extends exclusivity to mid-2029, reshaping post-2028 revenue outlook. Phase III EV-304 data showed approximately 50% reduction in recurrence or death for muscle-invasive bladder cancer with Padcev plus pembrolizumab. Ecnoglutide launched in China via partnership with Hangzhou Sciwind Biosciences. A Belgian court ruling on Comirnaty contracts and the Vyndamax settlement both improve cash-flow outlook. Full-year 2026 guidance was reaffirmed at $59.5–62.5B revenue and $2.80–3.00 adjusted EPS.

Guidance delta

2026 guidance was reaffirmed at $59.5–62.5B revenue and $2.80–3.00 adjusted EPS, unchanged from the prior quarter's outlook. Management tone remained confident. The dividend was maintained. No changes to the capital allocation framework were announced.

Key takeaways

  • Q1 revenue of $14.5B and adjusted EPS of $0.75 both beat consensus, with the launched/acquired portfolio growing 22% operationally to $3.1B.
  • Vyndamax patent settlement extends exclusivity to mid-2029, improving post-2028 revenue trajectory and supporting a high-single-digit CAGR starting 2029.
  • Phase III EV-304 data showed approximately 50% reduction in recurrence or death for muscle-invasive bladder cancer with Padcev plus pembrolizumab.
  • Pipeline momentum includes roughly 20 pivotal study starts, 8 key readouts, and 4 regulatory decisions planned for 2026.
  • Full-year 2026 guidance reaffirmed at $59.5–62.5B revenue and $2.80–3.00 adjusted EPS; dividend maintained.

Management priorities

  • Advance 10 Phase III studies and target first obesity approval in 2028
  • Further integrate Seagen assets and expand the ADC oncology platform
  • Launch 25-valent pediatric pneumococcal vaccine and fifth-generation adult vaccine covering 35 serotypes
  • Deploy AI across R&D, commercial, manufacturing, and enterprise functions
  • Scale Metsera obesity portfolio globally, leveraging primary-care capabilities

Related earnings events

Healthcare

Sources

  1. Earnings call transcript and parsed analysis · 2026-05-11T10:29:34.698584+00:00
  2. FN2 earnings calendar · 2026-07-26T00:36:15.940040+00:00
  3. Polygon adjusted daily market bars · 2026-07-28T20:41:43.619399+00:00
  4. Financial Modeling Prep analyst price-target consensus and quote snapshot · 2026-07-28T20:41:43.616722+00:00

Methodology

Reported and consensus figures come from FN2's earnings event records. Market reaction and volume are calculated from daily adjusted bars around the event; abnormal move subtracts the SPY move over the same window.

Analyst target low, average, and high values are derived at request time from each named analyst's latest persisted FMP target. The current-price marker comes from FN2's persisted market snapshot. They are sell-side estimates, not an FN2 valuation or recommendation.

Transcript intelligence is a structured synthesis of the current and prior earnings-call analyses. Missing values stay missing and are never estimated.

By FN2 Research · Updated . For educational purposes only; not investment advice.