Moderna, Inc. · MRNA · FY2025 Q4 · Calendar Q1 2026

Moderna raises outlook while regulatory and pipeline risks remain

The current analysis strengthens the case for a more constructive trajectory: management raised its guidance sentiment, cited up to 10% 2026 revenue growth, reported strong MNEXT Spike share, and highlighted pipeline progress. The thesis remains conditional because flu-program regulatory uncertainty, clinical readout timing, competition and international execution could limit delivery.

Reported Before market openNASDAQHealthcare $76.41B market cap
100quality score

Earnings scorecard

Reported versus consensus
Reported EPS $-2.11 Consensus $-2.54
EPS surprise +16.9% Reported versus consensus
Reported revenue $678.0M Consensus $635.2M
Revenue surprise +6.7% Reported versus consensus

Market reaction

prior-close to event-session close
Stock move +5.3% Event window
SPY move +0.1% Same window
Abnormal move +5.2% Stock minus SPY
Volume 1.2× Versus trailing sessions
Subsequent drift +26.2% Up to 20 sessions
MRNASPY benchmark

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Transcript intelligence

What changed

Compared with the prior analysis, the current analysis describes raised rather than lowered guidance sentiment, higher reported cash of $8.1 billion, up to 10% 2026 revenue growth, leading MNEXT Spike U.S. retail share, and additional international and pipeline progress. Regulatory uncertainty around mRNA-1010 is now a more prominent constraint.

Guidance delta

Management’s guidance sentiment shifted from lowered in the prior analysis to raised in the current analysis, with the 2026 outlook targeting up to 10% revenue growth.

Key takeaways

  • Management highlighted 2025 revenue of $1.9 billion and a narrowed net loss after significant cost reductions.
  • MNEXT Spike reached 24% overall U.S. retail share and 34% among seniors 65+ in the supplied analysis.
  • The 2026 outlook targets up to 10% revenue growth, supported by international expansion and local manufacturing.
  • Late-stage oncology, flu, norovirus and rare-disease programs remain important pipeline drivers.
  • Cash ended at $8.1 billion, while the flu program faces regulatory uncertainty after an FDA refusal-to-file letter.

Management priorities

  • Expand MNEXT Spike internationally, including planned regulatory submissions in Europe, Japan and Taiwan.
  • Advance mRNA-1010 and mRNA-1083 filings and prepare the U.S. flu-vaccine refiling.
  • Complete readouts for INT adjuvant melanoma, renal cell carcinoma and bladder cancer studies.
  • Begin local vaccine manufacturing in the U.K. and Australia in 2026.
  • Launch the propionic-acidemia commercialization collaboration with Recordati.

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Earnings History

Estimate Beat Miss Match
MRNA EPS earnings history estimate and actual scatter chart 9 reported fiscal quarters and 3 future estimate-only quarters. Q4 '23 estimate $-0.97 Q4 '23 actual $0.55, beat Q1 '24 estimate $-3.56 Q1 '24 actual $-3.07, beat Q2 '24 estimate $-3.35 Q2 '24 actual $-3.33, beat Q3 '24 estimate $-1.90 Q3 '24 actual $0.03, beat Q2 '25 estimate $-2.99 Q2 '25 actual $-2.13, beat Q3 '25 estimate $-1.87 Q3 '25 actual $-0.51, beat Q4 '25 estimate $-2.54 Q4 '25 actual $-2.11, beat Q1 '26 estimate $-4.45 Q1 '26 actual $-3.40, beat Q2 '26 estimate $-2.03 Q2 '26 actual $-1.97, beat Q3 '26 estimate $-1.10 Q4 '26 estimate $-1.96 Q1 '27 estimate $-1.81
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Analyst Consensus ?

ConsensusHold29 ratings
Bullish827.6%
Neutral1655.2%
Bearish517.2%

Analyst 52W Price Targets

$199.83Current
$15Low
$115.12Average
$350High

Latest persisted target per named analyst; persisted current price from FN2's market snapshot as of Oct 1, 2026. Not an FN2 forecast.

Firm-level rating actions

FMP grade actions identify the grading firm, not a named analyst.

FirmRatingPrior ratingActionDate
Rothschild & Co Sell NeutralDowngradeSep 3, 2026
Argus Research Buy HoldUpgradeAug 28, 2026
Wolfe Research Peer Perform UnderperformUpgradeAug 25, 2026
Barclays Equal Weight Equal WeightMaintainAug 24, 2026
JP Morgan Underweight UnderweightMaintainAug 21, 2026
Show 24 more rating actions

Named analyst price targets

Upside is calculated against the persisted current price $199.83. FMP does not supply a rating on these named-analyst rows.

FirmAnalyst52W targetPrice when postedUpsideDate
UBSAnalyst unavailable$81$150.81 -59.5%Sep 3, 2026
Argus ResearchJohn Eade$180$142.77 -9.9%Aug 28, 2026
BarclaysEliana Merle$125$145.13 -37.4%Aug 24, 2026
UBSMichael Yee$150$174.38 -24.9%Aug 20, 2026
Goldman SachsAnalyst unavailable$120$174.38 -39.9%Aug 19, 2026
See 85 more

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Company context

Snapshot as of publication

Moderna, Inc., a biotechnology firm, is dedicated to the discovery, development, and commercialization of messenger RNA (mRNA) based therapies and preventive medicines. Its extensive research and development efforts target a broad spectrum of medical needs, including infectious diseases, cancer immunology, rare conditions, cardiovascular ailments, and autoimmune disorders, with operations spanning the United States, Europe, and other global markets. The company's diverse product pipeline encompasses various vaccine candidates: those for respiratory illnesses like COVID-19, influenza, and respiratory syncytial virus (RSV); latent viral infections such as cytomegalovirus (CMV), Epstein-Barr virus (EBV), human immunodeficiency virus (HIV), herpes simplex virus (HSV), and varicella-zoster virus (VZV); and public health threats like Zika and Nipah.…

Historical context

All MRNA earnings

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Latest beats and misses

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Sources

  1. Earnings call transcript and parsed analysis · 2026-05-11T10:29:34.698584+00:00
  2. FN2 earnings calendar · 2026-07-26T00:37:12.209961+00:00
  3. Polygon adjusted daily market bars · 2026-10-01T11:56:12.407058+00:00
  4. Financial Modeling Prep analyst price-target consensus and quote snapshot · 2026-10-01T11:56:12.404138+00:00

Methodology

Reported and consensus figures come from FN2's earnings event records. Market reaction and volume are calculated from daily adjusted bars around the event; abnormal move subtracts the SPY move over the same window.

Analyst target low, average, and high values are derived at request time from each named analyst's latest persisted FMP target. The current-price marker comes from FN2's persisted market snapshot. They are sell-side estimates, not an FN2 valuation or recommendation.

Transcript intelligence is a structured synthesis of the current and prior earnings-call analyses. Missing values stay missing and are never estimated.

By FN2 Research · Updated · As of 2026-10-01. For educational purposes only; not investment advice.