Merck & Co., Inc. · MRK · FY2026 Q1 · Calendar Q2 2026

Merck Q1 2026: Revenue Beat and Raised Guidance, But One-Time Charges Weigh on EPS

Merck's Q1 2026 results underscore a company in transition: core Keytruda revenue remains strong, but the earnings profile is being reshaped by large one-time charges (Cidara: $9B) and strategic bets (pending Terns acquisition, Google Cloud AI partnership). Revenue beat consensus by roughly $440M, growing 5% YoY on oncology and animal-health strength. Management raised full-year EPS guidance to $5.04-$5.16, reflecting operational confidence. The pipeline showed breadth with FDA approval of IDVYNSO for HIV, priority reviews for I-DXd and WELIREG combinations, and over 20 planned product launches. However, Gardasil's 22% decline on China and Japan weakness and the approaching Keytruda LOE in 2028-2029 remain meaningful headwinds. The market initially reacted negatively (-2.6% abnormal move) but subsequently drifted +8.7% higher, suggesting investors ultimately looked past the one-time…

Reported Before market openNYSEHealthcare $322.95B market cap
100quality score

Company context

Snapshot as of publication

Merck & Co., Inc. is a global healthcare leader with operations spanning two core divisions: Pharmaceuticals and Animal Health. The Pharmaceutical segment is dedicated to human health, offering a broad spectrum of medicinal products. These cover crucial therapeutic areas such as oncology, acute hospital care, immunology, neuroscience, virology, cardiovascular conditions, and diabetes. This division also develops vital preventive vaccines for pediatric, adolescent, and adult populations. Meanwhile, the Animal Health segment focuses on the research, development, manufacturing, and marketing of veterinary medications, vaccines, and comprehensive health management solutions for animals. This division further provides innovative digital products designed for animal identification, traceability, and continuous monitoring.…

Earnings scorecard

Reported versus consensus
Reported EPS $-1.28 Consensus $-1
EPS surprise +12.9% Reported versus consensus
Reported revenue $16.29B Consensus $15.85B
Revenue surprise +2.8% Reported versus consensus

Earnings History

Estimate Beat Miss Match
MRK EPS earnings history estimate and actual scatter chart 9 reported fiscal quarters and 3 future estimate-only quarters. Q1 '24 estimate $1.88 Q1 '24 actual $2.07, beat Q2 '24 estimate $2.15 Q2 '24 actual $2.28, beat Q3 '24 estimate $1.50 Q3 '24 actual $1.57, beat Q2 '25 estimate $2.03 Q2 '25 actual $2.13, beat Q3 '25 estimate $2.36 Q3 '25 actual $2.58, beat Q4 '25 estimate $2.01 Q4 '25 actual $2.04, beat Q1 '26 estimate $-1.47 Q1 '26 actual $-1.28, beat Q2 '26 estimate $-0.27 Q2 '26 actual $-0.13, beat Q3 '26 estimate $2.22 Q4 '26 estimate $1.96 Q1 '27 estimate $2.21
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Analyst Consensus ?

ConsensusBuy37 ratings
Bullish2567.6%
Neutral1129.7%
Bearish12.7%

Analyst 52W Price Targets

$144.71Previous close
$80Low
$135.49Average
$180High

Latest persisted target per named analyst; persisted previous close from FN2's market snapshot as of Sep 11, 2026. Not an FN2 forecast.

Firm-level rating actions

FMP grade actions identify the grading firm, not a named analyst.

FirmRatingPrior ratingActionDate
Leerink Partners Outperform OutperformMaintainSep 9, 2026
Guggenheim Buy BuyMaintainSep 8, 2026
Wells Fargo Overweight OverweightMaintainSep 4, 2026
Wolfe Research Outperform OutperformMaintainAug 25, 2026
Argus Research Buy BuyMaintainAug 25, 2026
Goldman Sachs Buy BuyMaintainAug 21, 2026
UBS Buy BuyMaintainAug 20, 2026
RBC Capital Sector Perform OutperformDowngradeAug 20, 2026
Morgan Stanley Overweight Equal WeightUpgradeAug 20, 2026
BMO Capital Outperform OutperformMaintainAug 20, 2026
Daiwa Capital Outperform NeutralUpgradeAug 12, 2026
Barclays Overweight OverweightMaintainJul 29, 2026
JP Morgan Overweight OverweightMaintainJul 13, 2026
Cantor Fitzgerald Neutral NeutralMaintainJul 6, 2026
Scotiabank Sector Outperform Sector OutperformMaintainJun 30, 2026
B of A Securities Buy BuyMaintainJun 30, 2026
Citigroup Neutral NeutralMaintainMar 20, 2026
Freedom Broker Hold HoldMaintainFeb 9, 2026
TD Cowen Hold HoldMaintainJan 20, 2026
Deutsche Bank Hold HoldMaintainNov 18, 2025
Berenberg Hold BuyDowngradeSep 17, 2025
Truist Securities Hold BuyDowngradeJan 8, 2025
Societe Generale Sell HoldDowngradeMar 11, 2024
Atlantic Equities Overweight OverweightMaintainMay 1, 2023
Credit Suisse Outperform OutperformMaintainMar 7, 2023
SVB Leerink Outperform OutperformMaintainFeb 3, 2023
Erste Group Buy HoldUpgradeAug 25, 2022
Cowen & Co. Market Perform Market PerformMaintainJun 27, 2022
Bank of America Buy BuyMaintainMay 1, 2019
SunTrust Robinson Humphrey Buy BuyMaintainOct 29, 2018
DZ Bank Buy HoldUpgradeFeb 13, 2018
Leerink Swann Market Perform Market PerformMaintainFeb 6, 2018
Jefferies Hold UnderperformUpgradeOct 31, 2017
Bernstein Outperform Market PerformUpgradeJan 5, 2015
MainFirst Bank AG Outperform UnderperformUpgradeJul 28, 2014
Mainfirst Outperform UnderperformUpgradeJul 28, 2014
MKM Partners Buy BuyMaintainApr 14, 2014
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Named analyst price targets

Upside is calculated against the persisted previous close $144.71. FMP does not supply a rating on these named-analyst rows.

FirmAnalyst52W targetPrice when postedUpsideDate
HSBCAnalyst unavailable$172$147.6 +18.9%Sep 10, 2026
Leerink PartnersAnalyst unavailable$161$148.49 +11.3%Sep 9, 2026
GuggenheimVamil Divan$170$150.34 +17.5%Sep 8, 2026
Wells FargoAnalyst unavailable$170$152.34 +17.5%Sep 4, 2026
Argus ResearchJasper Hellweg$170$153.61 +17.5%Aug 25, 2026
Wolfe ResearchAlexandria Hammond$180$150.69 +24.4%Aug 25, 2026
Goldman SachsAnalyst unavailable$160$149.25 +10.6%Aug 21, 2026
BMO CapitalAnalyst unavailable$170$149.65 +17.5%Aug 20, 2026
UBSAnalyst unavailable$175$152.22 +20.9%Aug 20, 2026
RBC CapitalAnalyst unavailable$150$152.22 +3.7%Aug 20, 2026
UBSMatthew Weston$150$152.22 +3.7%Aug 20, 2026
Morgan StanleyAnalyst unavailable$179$152.22 +23.7%Aug 19, 2026
DaiwaAnalyst unavailable$143$130.45 -1.2%Aug 12, 2026
Argus ResearchJasper Hellweg$145$130.9 +0.2%Aug 11, 2026
Morgan StanleyTerence Flynn$116$130.4 -19.8%Aug 5, 2026
GuggenheimVamil Divan$146$128.04 +0.9%Aug 5, 2026
BarclaysEmily Field$150$131.84 +3.7%Jul 29, 2026
BernsteinCourtney Breen$105$132.34 -27.4%Jul 27, 2026
BMO CapitalAnalyst unavailable$142$124.08 -1.9%Jul 13, 2026
GuggenheimVamil Divan$145$123.54 +0.2%Jul 13, 2026
HSBCRajesh Kumar$150$126.05 +3.7%Jul 6, 2026
JefferiesAnalyst unavailable$141$129.38 -2.6%Jun 30, 2026
ScotiabankAnalyst unavailable$155$129.38 +7.1%Jun 29, 2026
GuggenheimVamil Divan$140$115.21 -3.3%Jun 2, 2026
Morgan StanleyTerence Flynn$112$112.47 -22.6%May 1, 2026
Wells FargoMohit Bansal$150$116.22 +3.7%Mar 12, 2026
RBC CapitalTrung Huynh$142$123.93 -1.9%Feb 24, 2026
Deutsche BankJames Shin$150$121.53 +3.7%Feb 13, 2026
Goldman SachsAsad Haider$133$115.86 -8.1%Feb 4, 2026
BMO CapitalAnalyst unavailable$135$115.86 -6.7%Feb 4, 2026
BernsteinAnalyst unavailable$100$115.86 -30.9%Feb 4, 2026
ScotiabankAnalyst unavailable$136$116.37 -6.0%Feb 3, 2026
Cantor FitzgeraldAnalyst unavailable$116$107.4 -19.8%Jan 27, 2026
Wolfe ResearchAnalyst unavailable$135$108.59 -6.7%Jan 8, 2026
UBSAnalyst unavailable$130$110.96 -10.2%Jan 7, 2026
BMO CapitalAnalyst unavailable$130$99.21 -10.2%Dec 18, 2025
Morgan StanleyAnalyst unavailable$102$100.06 -29.5%Dec 12, 2025
HSBCRajesh Kumar$120$96.89 -17.1%Dec 10, 2025
GuggenheimAnalyst unavailable$122$100.89 -15.7%Dec 5, 2025
ScotiabankLouise Chen$120$101.88 -17.1%Dec 4, 2025
Goldman SachsAsad Haider$120$101.83 -17.1%Dec 2, 2025
Morgan StanleyTerence Flynn$100$84.65 -30.9%Nov 3, 2025
Berenberg BankLuisa Hector$90$81.14 -37.8%Sep 17, 2025
Morgan StanleyTerence Flynn$98$84.39 -32.3%Jul 10, 2025
BMO CapitalEvan Seigerman$82$82.74 -43.3%Apr 25, 2025
Morgan StanleyTerence Flynn$106$90.74 -26.8%Feb 5, 2025
BernsteinCourtney Breen$110$100.69 -24.0%Dec 2, 2024
JefferiesAkash Tewari$148$98.36 +2.3%Nov 15, 2024
BMO CapitalEvan David Seigerman$136$101.88 -6.0%Nov 1, 2024
UBSTrung Huynh$136$108.88 -6.0%Oct 9, 2024
BarclaysCarter Gould$140$109.77 -3.3%Oct 7, 2024
JefferiesAkash Tewari$147$113.49 +1.6%Aug 15, 2024
UBSColin Bristow$142$112.89 -1.9%Jul 31, 2024
Bank of America SecuritiesGeoff Meacham$145$115.21 +0.2%Jul 31, 2024
Wells FargoMohit Bansal$140$131.05 -3.3%Jun 12, 2024
BMO CapitalEvan David Seigerman$148$127.71 +2.3%May 30, 2024
Truist FinancialAnalyst unavailable$142$130.81 -1.9%Mar 27, 2024
JefferiesAkash Tewari$145$130.18 +0.2%Mar 27, 2024
Wells FargoMohit Bansal$135$130.19 -6.7%Mar 27, 2024
Loop Capital MarketsEvan David Seigerman$132$101.44 -8.8%Nov 22, 2023
OppenheimerJay Olson$147$56.34 +1.6%Apr 12, 2023
Wells FargoAnalyst unavailable$120$103.28 -17.1%Feb 3, 2023
Morgan StanleyAnalyst unavailable$99$103.46 -31.6%Feb 3, 2023
Wells FargoAnalyst unavailable$125$110.62 -13.6%Jan 3, 2023
Cantor FitzgeraldAnalyst unavailable$135$109.2 -6.7%Dec 19, 2022
Credit SuisseAnalyst unavailable$120$102.31 -17.1%Nov 18, 2022
Leerink PartnersAnalyst unavailable$110$86.64 -24.0%Sep 30, 2022
Leerink PartnersAnalyst unavailable$109$87.34 -24.7%Sep 12, 2022
BarclaysAnalyst unavailable$101$88.62 -30.2%Jul 29, 2022
Morgan StanleyAnalyst unavailable$92$89.26 -36.4%Jul 29, 2022
Leerink PartnersAnalyst unavailable$105$89.94 -27.4%Jul 29, 2022
UBSAnalyst unavailable$98$94.34 -32.3%Jul 18, 2022
Atlantic EquitiesAnalyst unavailable$110$93.6 -24.0%Jul 13, 2022
Morgan StanleyAnalyst unavailable$88$93.01 -39.2%Jul 8, 2022
Morgan StanleyAnalyst unavailable$87$88.62 -39.9%Apr 29, 2022
Leerink PartnersAnalyst unavailable$102$88.58 -29.5%Apr 29, 2022
Leerink PartnersAnalyst unavailable$97$86.46 -33.0%Apr 21, 2022
BarclaysCarter Gould$97$86.91 -33.0%Apr 16, 2022
Morgan StanleyTerence Flynn$80$86.63 -44.7%Apr 11, 2022
BMO CapitalEvan David Seigerman$87$87.68 -39.9%Apr 10, 2022
Goldman SachsChris Shibutani$93$75.02 -35.7%Dec 17, 2021
UBSColin Bristow$76$72.09 -47.5%Dec 13, 2021
CitigroupAndrew Baum$85$73.53 -41.3%Nov 29, 2021
Argus ResearchDavid Toung$110$86.25 -24.0%Nov 1, 2021
BarclaysCarter Gould$94$86.25 -35.0%Nov 1, 2021
Bank of America SecuritiesGeoff Meacham$86$86.45 -40.6%Oct 29, 2021
Wolfe ResearchTim Anderson$94$86.45 -35.0%Oct 29, 2021
RBC CapitalDaniel Busby$80$74.86 -44.7%Jul 29, 2021
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Market reaction

prior-close to event-session close
Stock move -1.6% Event window
SPY move +1.0% Same window
Abnormal move -2.6% Stock minus SPY
Volume 1.9× Versus trailing sessions
Subsequent drift +8.7% Up to 20 sessions
MRKSPY benchmark

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Transcript intelligence

What changed

Revenue beat consensus by roughly $440M ($16.29B vs. $15.85B est.), up 5% YoY. EPS beat despite the one-time Cidara charge (-$1.28 vs. -$1.47 est.). Full-year EPS guidance raised to $5.04-$5.16 from $5.00-$5.15. New FDA approval of IDVYNSO for HIV. Priority reviews granted for I-DXd (small-cell lung cancer) and WELIREG combinations. Pending Terns Pharmaceuticals acquisition announced with ~$5.8B expected increase in R&D expense. Google Cloud AI partnership launched. Gardasil sales fell 22% on weak China and Japan demand. Keytruda Q3 timing headwind flagged from earlier wholesaler purchasing.

Guidance delta

Full-year EPS guidance raised from $5.00-$5.15 to $5.04-$5.16, with revenue guidance also increased. Guidance sentiment was raised, reflecting operational strength in oncology and animal health despite one-time acquisition charges.

Key takeaways

  • Q1 revenue of $16.3B beat consensus by roughly $440M, up 5% YoY on oncology and animal-health strength
  • EPS guidance raised to $5.04-$5.16 despite a $9B one-time Cidara acquisition charge pushing quarterly EPS to -$1.28 (still ahead of the -$1.47 consensus)
  • FDA approval of IDVYNSO for HIV and priority reviews for I-DXd (small-cell lung cancer) and WELIREG combinations expand near-term commercial opportunity
  • Pending Terns Pharmaceuticals acquisition and Google Cloud AI partnership signal investment in pipeline depth and operational efficiency
  • Gardasil sales fell 22% on weaker demand in China and Japan, a persistent headwind
  • Stock initially dropped 2.6% on the print but subsequently drifted 8.7% higher, suggesting investors looked past one-time charges to the raised outlook

Management priorities

  • Deliver multiple Phase III data readouts over the next 18 months across oncology, cardiometabolic, and ophthalmology
  • Complete the Terns Pharmaceuticals acquisition and integrate TERN-701 for chronic myeloid leukemia
  • Roll out AI capabilities company-wide through the Google Cloud partnership
  • Launch and commercialize over 20 new products across therapeutic areas
  • Implement the new product-focused commercial business-unit model

Related earnings events

Healthcare

Sources

  1. Earnings call transcript and parsed analysis · 2026-05-11T10:29:34.698584+00:00
  2. FN2 earnings calendar · 2026-07-26T00:37:12.209961+00:00
  3. Polygon adjusted daily market bars · 2026-07-28T09:51:20.553753+00:00
  4. Financial Modeling Prep analyst price-target consensus and quote snapshot · 2026-07-28T09:51:20.550881+00:00

Methodology

Reported and consensus figures come from FN2's earnings event records. Market reaction and volume are calculated from daily adjusted bars around the event; abnormal move subtracts the SPY move over the same window.

Analyst target low, average, and high values are derived at request time from each named analyst's latest persisted FMP target. The current-price marker comes from FN2's persisted market snapshot. They are sell-side estimates, not an FN2 valuation or recommendation.

Transcript intelligence is a structured synthesis of the current and prior earnings-call analyses. Missing values stay missing and are never estimated.

By FN2 Research · Updated . For educational purposes only; not investment advice.