Merck & Co., Inc. · MRK · FY2026 Q1 · Calendar Q2 2026

Merck Q1 2026: Revenue Beat and Raised Guidance, But One-Time Charges Weigh on EPS

Merck's Q1 2026 results underscore a company in transition: core Keytruda revenue remains strong, but the earnings profile is being reshaped by large one-time charges (Cidara: $9B) and strategic bets (pending Terns acquisition, Google Cloud AI partnership). Revenue beat consensus by roughly $440M, growing 5% YoY on oncology and animal-health strength. Management raised full-year EPS guidance to $5.04-$5.16, reflecting operational confidence. The pipeline showed breadth with FDA approval of IDVYNSO for HIV, priority reviews for I-DXd and WELIREG combinations, and over 20 planned product launches. However, Gardasil's 22% decline on China and Japan weakness and the approaching Keytruda LOE in 2028-2029 remain meaningful headwinds. The market initially reacted negatively (-2.6% abnormal move) but subsequently drifted +8.7% higher, suggesting investors ultimately looked past the one-time…

Reported Before market openNYSEHealthcare $322.95B market cap
100quality score

Company context

Snapshot as of publication

Merck & Co., Inc. is a global healthcare leader with operations spanning two core divisions: Pharmaceuticals and Animal Health. The Pharmaceutical segment is dedicated to human health, offering a broad spectrum of medicinal products. These cover crucial therapeutic areas such as oncology, acute hospital care, immunology, neuroscience, virology, cardiovascular conditions, and diabetes. This division also develops vital preventive vaccines for pediatric, adolescent, and adult populations. Meanwhile, the Animal Health segment focuses on the research, development, manufacturing, and marketing of veterinary medications, vaccines, and comprehensive health management solutions for animals. This division further provides innovative digital products designed for animal identification, traceability, and continuous monitoring.…

Earnings scorecard

Reported versus consensus
Reported EPS $-1.28 Consensus $-1
EPS surprise +12.9% Reported versus consensus
Reported revenue $16.29B Consensus $15.85B
Revenue surprise +2.8% Reported versus consensus

Earnings History

Estimate Beat Miss Match
MRK REVENUE earnings history estimate and actual scatter chart 9 reported fiscal quarters and 3 future estimate-only quarters. Q4 '23 estimate $14B Q4 '23 actual $15B, beat Q1 '24 estimate $15B Q1 '24 actual $16B, beat Q2 '24 estimate $16B Q2 '24 actual $16B, beat Q3 '24 estimate $16B Q3 '24 actual $17B, beat Q2 '25 estimate $16B Q2 '25 actual $16B, miss Q3 '25 estimate $17B Q3 '25 actual $17B, beat Q4 '25 estimate $16B Q4 '25 actual $16B, beat Q1 '26 estimate $16B Q1 '26 actual $16B, beat Q2 '26 estimate $16B Q2 '26 actual $17B, beat Q3 '26 estimate $17B Q4 '26 estimate $17B Q1 '27 estimate $17B
Show less

Analyst Consensus ?

ConsensusBuy37 ratings
Bullish2567.6%
Neutral1129.7%
Bearish12.7%

Analyst 52W Price Targets

$144.71Previous close
$80Low
$135.49Average
$180High

Latest persisted target per named analyst; persisted previous close from FN2's market snapshot as of Sep 11, 2026. Not an FN2 forecast.

Firm-level rating actions

FMP grade actions identify the grading firm, not a named analyst.

FirmRatingPrior ratingActionDate
Leerink Partners Outperform OutperformMaintainSep 9, 2026
Guggenheim Buy BuyMaintainSep 8, 2026
Wells Fargo Overweight OverweightMaintainSep 4, 2026
Wolfe Research Outperform OutperformMaintainAug 25, 2026
Argus Research Buy BuyMaintainAug 25, 2026
Goldman Sachs Buy BuyMaintainAug 21, 2026
UBS Buy BuyMaintainAug 20, 2026
RBC Capital Sector Perform OutperformDowngradeAug 20, 2026
Show 29 more rating actions

Named analyst price targets

Upside is calculated against the persisted previous close $144.71. FMP does not supply a rating on these named-analyst rows.

FirmAnalyst52W targetPrice when postedUpsideDate
HSBCAnalyst unavailable$172$147.6 +18.9%Sep 10, 2026
Leerink PartnersAnalyst unavailable$161$148.49 +11.3%Sep 9, 2026
GuggenheimVamil Divan$170$150.34 +17.5%Sep 8, 2026
Wells FargoAnalyst unavailable$170$152.34 +17.5%Sep 4, 2026
Argus ResearchJasper Hellweg$170$153.61 +17.5%Aug 25, 2026
Wolfe ResearchAlexandria Hammond$180$150.69 +24.4%Aug 25, 2026
Goldman SachsAnalyst unavailable$160$149.25 +10.6%Aug 21, 2026
BMO CapitalAnalyst unavailable$170$149.65 +17.5%Aug 20, 2026
UBSAnalyst unavailable$175$152.22 +20.9%Aug 20, 2026
RBC CapitalAnalyst unavailable$150$152.22 +3.7%Aug 20, 2026
See 78 more

Track every rating change on MRK the moment it posts. Free to start.

Start free

Market reaction

prior-close to event-session close
Stock move -1.6% Event window
SPY move +1.0% Same window
Abnormal move -2.6% Stock minus SPY
Volume 1.9× Versus trailing sessions
Subsequent drift +8.7% Up to 20 sessions
MRKSPY benchmark

Follow MRK with an agent that reads every filing, transcript, and price print. Free to start.

Try FN2 free

Transcript intelligence

What changed

Revenue beat consensus by roughly $440M ($16.29B vs. $15.85B est.), up 5% YoY. EPS beat despite the one-time Cidara charge (-$1.28 vs. -$1.47 est.). Full-year EPS guidance raised to $5.04-$5.16 from $5.00-$5.15. New FDA approval of IDVYNSO for HIV. Priority reviews granted for I-DXd (small-cell lung cancer) and WELIREG combinations. Pending Terns Pharmaceuticals acquisition announced with ~$5.8B expected increase in R&D expense. Google Cloud AI partnership launched. Gardasil sales fell 22% on weak China and Japan demand. Keytruda Q3 timing headwind flagged from earlier wholesaler purchasing.

Guidance delta

Full-year EPS guidance raised from $5.00-$5.15 to $5.04-$5.16, with revenue guidance also increased. Guidance sentiment was raised, reflecting operational strength in oncology and animal health despite one-time acquisition charges.

Key takeaways

  • Q1 revenue of $16.3B beat consensus by roughly $440M, up 5% YoY on oncology and animal-health strength
  • EPS guidance raised to $5.04-$5.16 despite a $9B one-time Cidara acquisition charge pushing quarterly EPS to -$1.28 (still ahead of the -$1.47 consensus)
  • FDA approval of IDVYNSO for HIV and priority reviews for I-DXd (small-cell lung cancer) and WELIREG combinations expand near-term commercial opportunity
  • Pending Terns Pharmaceuticals acquisition and Google Cloud AI partnership signal investment in pipeline depth and operational efficiency
  • Gardasil sales fell 22% on weaker demand in China and Japan, a persistent headwind
  • Stock initially dropped 2.6% on the print but subsequently drifted 8.7% higher, suggesting investors looked past one-time charges to the raised outlook

Management priorities

  • Deliver multiple Phase III data readouts over the next 18 months across oncology, cardiometabolic, and ophthalmology
  • Complete the Terns Pharmaceuticals acquisition and integrate TERN-701 for chronic myeloid leukemia
  • Roll out AI capabilities company-wide through the Google Cloud partnership
  • Launch and commercialize over 20 new products across therapeutic areas
  • Implement the new product-focused commercial business-unit model

Related earnings events

Healthcare

Sources

  1. Earnings call transcript and parsed analysis · 2026-05-11T10:29:34.698584+00:00
  2. FN2 earnings calendar · 2026-07-26T00:37:12.209961+00:00
  3. Polygon adjusted daily market bars · 2026-07-28T09:51:20.553753+00:00
  4. Financial Modeling Prep analyst price-target consensus and quote snapshot · 2026-07-28T09:51:20.550881+00:00

Methodology

Reported and consensus figures come from FN2's earnings event records. Market reaction and volume are calculated from daily adjusted bars around the event; abnormal move subtracts the SPY move over the same window.

Analyst target low, average, and high values are derived at request time from each named analyst's latest persisted FMP target. The current-price marker comes from FN2's persisted market snapshot. They are sell-side estimates, not an FN2 valuation or recommendation.

Transcript intelligence is a structured synthesis of the current and prior earnings-call analyses. Missing values stay missing and are never estimated.

By FN2 Research · Updated . For educational purposes only; not investment advice.