Eli Lilly and Company · LLY · FY2026 Q1 · Calendar Q2 2026

Eli Lilly Beats on Revenue and EPS as Foundayo Launch Ignites 56% Growth

Q1 2026 marks a pivotal quarter for Eli Lilly. The FDA approval and commercial launch of Foundayo, the first oral GLP-1 therapy for obesity, adds a major new growth engine alongside continued Mounjaro and Zepbound dominance. Revenue grew 56% YoY to $19.8B, exceeding consensus by over $2B, while EPS of $8.55 surpassed estimates by 23%. Management raised full-year guidance to $82-$85B in revenue and $35.50-$37 in non-GAAP EPS, reflecting confidence that volume expansion can absorb U.S. pricing pressure. A session move of nearly 10% and subsequent drift of 18% suggest investors are pricing in sustained incretin franchise leadership. Execution on Foundayo scaling, manufacturing capacity buildout, and access program effectiveness will determine whether that trajectory holds.

Reported Before market openNYSEHealthcare $1128.20B market cap
100quality score

Earnings scorecard

Reported versus consensus
Reported EPS $8.55 Consensus $6.97
EPS surprise +22.7% Reported versus consensus
Reported revenue $19.80B Consensus $17.82B
Revenue surprise +11.1% Reported versus consensus

Market reaction

prior-close to event-session close
Stock move +9.8% Event window
SPY move +1.0% Same window
Abnormal move +8.8% Stock minus SPY
Volume 2.8× Versus trailing sessions
Subsequent drift +18.2% Up to 20 sessions
LLYSPY benchmark

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What changed

Revenue growth accelerated to 56% YoY from 45% full-year growth in 2025. Foundayo, the first FDA-approved oral GLP-1 for obesity, launched with high prescriber uptake and retail and telehealth availability. Full-year 2026 guidance was raised from $80-$83B revenue and $33.50-$35 EPS to $82-$85B revenue and $35.50-$37 non-GAAP EPS. Six strategic acquisitions were announced (Orna, Syntessa, Colonia, Ajax, Ventix, Contessa) to expand pipeline platforms including CAR-T, JAK inhibitors, and NLRP3 inhibitors. New access initiatives launched: Lilly Employer Connect platform and an extended Medicare GLP-1 bridge program through 2027 with a $50/month co-pay for seniors.

Guidance delta

Full-year 2026 revenue guidance raised from $80-$83B to $82-$85B. Non-GAAP EPS guidance raised from $33.50-$35 to $35.50-$37. Both the revenue floor and ceiling moved up by approximately $2B, and the EPS range shifted higher by roughly $2 at both ends, reflecting Foundayo contribution and sustained incretin volume growth.

Key takeaways

  • Revenue reached $19.8B, up 56% YoY, driven by Mounjaro, Foundayo, and broad therapeutic-area strength
  • EPS of $8.55 beat consensus of $6.97 by 22.7%; revenue exceeded estimates by 11.1%
  • Foundayo, the first FDA-approved oral GLP-1 for obesity, launched with high prescriber uptake and retail/telehealth availability
  • Multiple Phase III readouts were positive across obesity, diabetes, immunology, oncology, and neuroscience
  • Six acquisitions (Orna, Syntessa, Colonia, Ajax, Ventix, Contessa) add CAR-T, JAK inhibitor, and NLRP3 inhibitor platforms
  • Full-year 2026 guidance raised to $82-$85B revenue and $35.50-$37 non-GAAP EPS

Management priorities

  • Scale Foundayo launch and submit for type 2 diabetes indication in late Q2 2026
  • Read out Retatrutide Phase III obesity trial later this quarter
  • Expand Lilly Direct and DTC advertising for obesity medicines in Q3 2026
  • Continue Phase III programs for aloralentide, sofetobartin, mypatecan, and brinepatide
  • Integrate newly acquired assets into R&D pipeline
  • Broaden access through Employer Connect and Medicare bridge programs

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Earnings History

Estimate Beat Miss Match
LLY EPS earnings history estimate and actual scatter chart 9 reported fiscal quarters and 3 future estimate-only quarters. Q1 '24 estimate $2.46 Q1 '24 actual $2.58, beat Q2 '24 estimate $2.60 Q2 '24 actual $3.92, beat Q3 '24 estimate $1.47 Q3 '24 actual $1.18, miss Q2 '25 estimate $5.60 Q2 '25 actual $6.31, beat Q3 '25 estimate $5.69 Q3 '25 actual $7.02, beat Q4 '25 estimate $6.91 Q4 '25 actual $7.54, beat Q1 '26 estimate $6.97 Q1 '26 actual $8.55, beat Q2 '26 estimate $6.40 Q2 '26 actual $8.38, beat Q3 '26 estimate $5.70 Q4 '26 estimate $9.93 Q1 '27 estimate $9.26
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Analyst Consensus ?

ConsensusBuy45 ratings
Bullish3373.3%
Neutral920.0%
Bearish36.7%

Analyst 52W Price Targets

$1,279.58Current
$265Low
$1,007.88Average
$1,500High

Latest persisted target per named analyst; persisted current price from FN2's market snapshot as of Oct 26, 2026. Not an FN2 forecast.

Firm-level rating actions

FMP grade actions identify the grading firm, not a named analyst.

FirmRatingPrior ratingActionDate
Leerink Partners Outperform OutperformMaintainOct 21, 2026
RBC Capital Outperform OutperformMaintainOct 12, 2026
Cantor Fitzgerald Overweight OverweightMaintainOct 8, 2026
Morgan Stanley Overweight OverweightMaintainOct 7, 2026
JP Morgan Overweight OverweightMaintainSep 28, 2026
Show 40 more rating actions

Named analyst price targets

Upside is calculated against the persisted current price $1,279.58. FMP does not supply a rating on these named-analyst rows.

FirmAnalyst52W targetPrice when postedUpsideDate
Leerink PartnersAnalyst unavailable$1,316$1,265.92 +2.8%Oct 21, 2026
Goldman SachsAnalyst unavailable$1,413$1,300.46 +10.4%Oct 20, 2026
Cantor FitzgeraldCarter Gould$1,440$1,188.72 +12.5%Oct 8, 2026
Morgan StanleyAnalyst unavailable$1,430$1,184.48 +11.8%Oct 7, 2026
GuggenheimSeamus Fernandez$1,284$1,152.13 +0.3%Sep 18, 2026
See 130 more

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Company context

Snapshot as of publication

Eli Lilly and Company is a prominent global pharmaceutical firm dedicated to the research, development, and commercialization of human medicines across the world. Its therapeutic offerings include a comprehensive suite of diabetes medications. This encompasses various insulin formulations like Basaglar, the Humalog family (e.g., Mix 75/25, U-100, U-200, Mix 50/50), insulin lispro products (including protamine and mix 75/25), and the Humulin line (e.g., 70/30, N, R, U-500). Furthermore, Eli Lilly provides specialized treatments for type 2 diabetes, such as Jardiance, Trajenta, and Trulicity. In oncology, Eli Lilly offers a robust portfolio targeting various cancers. These include Alimta for non-small cell lung cancer (NSCLC) and malignant pleural mesothelioma; Cyramza, indicated for metastatic gastric cancer, gastro-esophageal junction adenocarcinoma, metastatic NSCLC, metastatic colorectal cancer, and hepatocellular carcinoma; Erbitux for colorectal and various head and neck cancers; Retevmo, used in metastatic NSCLC, medullary…

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Sources

  1. Earnings call transcript and parsed analysis · 2026-05-11T10:29:34.698584+00:00
  2. FN2 earnings calendar · 2026-07-26T00:37:12.209961+00:00
  3. Polygon adjusted daily market bars · 2026-07-28T05:32:02.862126+00:00
  4. Financial Modeling Prep analyst price-target consensus and quote snapshot · 2026-07-28T05:32:02.859302+00:00

Methodology

Reported and consensus figures come from FN2's earnings event records. Market reaction and volume are calculated from daily adjusted bars around the event; abnormal move subtracts the SPY move over the same window.

Analyst target low, average, and high values are derived at request time from each named analyst's latest persisted FMP target. The current-price marker comes from FN2's persisted market snapshot. They are sell-side estimates, not an FN2 valuation or recommendation.

Transcript intelligence is a structured synthesis of the current and prior earnings-call analyses. Missing values stay missing and are never estimated.

By FN2 Research · Updated · As of 2026-07-28. For educational purposes only; not investment advice.