Eli Lilly and Company · LLY · FY2024 Q4 · Calendar Q1 2025

Lilly: Strong incretin growth, with pricing and execution risks

The supplied analysis supports a constructive growth thesis for Lilly: incretin demand, new indications, international expansion, and manufacturing investment are intended to sustain growth. The thesis remains conditional on payer access, pricing, supply, pipeline execution, and competition.

Reported Before market openNYSEHealthcare $1178.21B market cap
80quality score

Earnings scorecard

Reported versus consensus
Reported EPS — Consensus $5.45
EPS surprise — Reported versus consensus
Reported revenue — Consensus $13.72B
Revenue surprise — Reported versus consensus

Market reaction

prior-close to event-session close
Stock move +3.3% Event window
SPY move +0.3% Same window
Abnormal move +3.0% Stock minus SPY
Volume 1.8× Versus trailing sessions
Subsequent drift -0.1% Up to 20 sessions
LLYSPY benchmark

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Transcript intelligence

What changed

Relative to the prior-quarter analysis, the supplied current analysis emphasizes continued strong incretin momentum, additional regulatory progress, further Phase III activity, and a larger manufacturing footprint. Guidance sentiment moved from raised in the prior analysis to maintained in the current analysis, while pricing, payer, litigation, and execution concerns remain.

Guidance delta

Maintained, according to the supplied transcript analysis; the analysis describes a 2025 outlook targeting 32% revenue growth and continued margin expansion.

Key takeaways

  • The supplied analysis describes 45% year-over-year Q4 revenue growth, with new products contributing more than $5.6 billion.
  • Management highlighted pipeline progress, including Phase III starts and approvals for Kisunla, Ebglyss, and Zepbound OSA.
  • The analysis identifies manufacturing expansion, geographic launches, and broader access as key supports for continued growth.
  • The main offsets are pricing and payer pressure, compounding litigation, competition, and execution risk on manufacturing investment.

Management priorities

  • Expand Mounjaro and Zepbound access and launch into additional markets.
  • Advance orforglipron and other Phase III programs toward future launches.
  • Expand manufacturing capacity across the planned site network.
  • Use direct-to-consumer access, payer work, collaborations, and strategic transactions to support growth.

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Earnings History

Estimate Beat Miss Match
LLY EPS earnings history estimate and actual scatter chart 9 reported fiscal quarters and 3 future estimate-only quarters. Q4 '23 estimate $2.22 Q4 '23 actual $2.49, beat Q1 '24 estimate $2.46 Q1 '24 actual $2.58, beat Q2 '24 estimate $2.60 Q2 '24 actual $3.92, beat Q3 '24 estimate $1.47 Q3 '24 actual $1.18, miss Q2 '25 estimate $5.60 Q2 '25 actual $6.31, beat Q3 '25 estimate $5.69 Q3 '25 actual $7.02, beat Q4 '25 estimate $6.91 Q4 '25 actual $7.54, beat Q1 '26 estimate $6.97 Q1 '26 actual $8.55, beat Q2 '26 estimate $6.40 Q2 '26 actual $8.38, beat Q3 '26 estimate $5.60 Q4 '26 estimate $9.93 Q1 '27 estimate $9.26
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Analyst Consensus ?

ConsensusBuy45 ratings
Bullish3373.3%
Neutral920.0%
Bearish36.7%

Analyst 52W Price Targets

$1,251.61Previous close
$265Low
$989.3Average
$1,500High

Latest persisted target per named analyst; persisted previous close from FN2's market snapshot as of Oct 16, 2026. Not an FN2 forecast.

Firm-level rating actions

FMP grade actions identify the grading firm, not a named analyst.

FirmRatingPrior ratingActionDate
RBC Capital Outperform OutperformMaintainOct 12, 2026
Cantor Fitzgerald Overweight OverweightMaintainOct 8, 2026
Morgan Stanley Overweight OverweightMaintainOct 7, 2026
JP Morgan Overweight OverweightMaintainSep 28, 2026
TD Cowen Buy BuyMaintainSep 22, 2026
Show 40 more rating actions

Named analyst price targets

Upside is calculated against the persisted previous close $1,251.61. FMP does not supply a rating on these named-analyst rows.

FirmAnalyst52W targetPrice when postedUpsideDate
Cantor FitzgeraldCarter Gould$1,440$1,188.72 +15.1%Oct 8, 2026
Morgan StanleyAnalyst unavailable$1,430$1,184.48 +14.3%Oct 7, 2026
GuggenheimSeamus Fernandez$1,284$1,152.13 +2.6%Sep 18, 2026
Berenberg BankKerry Holford$1,400$1,137.75 +11.9%Sep 15, 2026
HSBCAnalyst unavailable$940$1,124.16 -24.9%Sep 10, 2026
See 128 more

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Company context

Snapshot as of publication

Eli Lilly and Company is a prominent global pharmaceutical firm dedicated to the research, development, and commercialization of human medicines across the world. Its therapeutic offerings include a comprehensive suite of diabetes medications. This encompasses various insulin formulations like Basaglar, the Humalog family (e.g., Mix 75/25, U-100, U-200, Mix 50/50), insulin lispro products (including protamine and mix 75/25), and the Humulin line (e.g., 70/30, N, R, U-500). Furthermore, Eli Lilly provides specialized treatments for type 2 diabetes, such as Jardiance, Trajenta, and Trulicity. In oncology, Eli Lilly offers a robust portfolio targeting various cancers. These include Alimta for non-small cell lung cancer (NSCLC) and malignant pleural mesothelioma; Cyramza, indicated for metastatic gastric cancer, gastro-esophageal junction adenocarcinoma, metastatic NSCLC, metastatic colorectal cancer, and hepatocellular carcinoma; Erbitux for colorectal and various head and neck cancers; Retevmo, used in metastatic NSCLC, medullary…

Historical context

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Latest beats and misses

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Sources

  1. Earnings call transcript and parsed analysis · 2026-05-11T10:29:34.698584+00:00
  2. FN2 earnings calendar · 2025-01-23T00:02:36.799981+00:00
  3. Polygon adjusted daily market bars · 2026-10-16T10:00:42.670149+00:00
  4. Financial Modeling Prep analyst price-target consensus and quote snapshot · 2026-10-16T10:00:42.667498+00:00

Methodology

Reported and consensus figures come from FN2's earnings event records. Market reaction and volume are calculated from daily adjusted bars around the event; abnormal move subtracts the SPY move over the same window.

Analyst target low, average, and high values are derived at request time from each named analyst's latest persisted FMP target. The current-price marker comes from FN2's persisted market snapshot. They are sell-side estimates, not an FN2 valuation or recommendation.

Transcript intelligence is a structured synthesis of the current and prior earnings-call analyses. Missing values stay missing and are never estimated.

By FN2 Research · Updated · As of 2026-10-16. For educational purposes only; not investment advice.