Incyte Corporation · INCY · FY2026 Q1 · Calendar Q2 2026

Incyte Q1 Revenue Beats on 21% Growth, Pipeline Catalysts Accelerate Into 2026 Launches

Incyte is executing a multi-franchise transition beyond its flagship Jakafi franchise, and Q1 2026 delivered the first proof point that the growth thesis is tracking. Revenue of $1.27B beat consensus by 4.7% and EPS beat by 35%, driven by broad-based growth across hematology, oncology, and immunology. Management reaffirmed full-year guidance of $4.77-$4.94B and detailed four product launches planned for 2026 — Jakafi XR, Opzelura in Europe, Monjuvi in first-line DLBCL, and povorcitinib for HS — backed by regulatory milestones including an ahead-of-schedule FDA NDA acceptance for povorcitinib. The pipeline is maturing rapidly, with pivotal readouts expected from the 989 CALR antibody, 734 KRAS G12D inhibitor, and A90 programs. The bullish score rose to 82 from 78 the prior quarter, and the stock posted a +2.6% abnormal return on the report day. The key question for investors is whether…

Reported Before market openNASDAQHealthcare $25.39B market cap
100quality score

Company context

Snapshot as of publication

Incyte Corporation is a biopharmaceutical firm engaged in the research, development, and global marketing of its own innovative therapies. Its current product offerings include JAKAFI, prescribed for myelofibrosis and polycythemia vera; PEMAZYRE, a fibroblast growth factor receptor kinase inhibitor that targets oncogenic drivers in various liquid and solid tumor types; and ICLUSIG, a kinase inhibitor utilized for chronic myeloid leukemia and Philadelphia-chromosome positive acute lymphoblastic leukemia. Beyond its marketed drugs, Incyte's pipeline features several promising candidates. Among its clinical-stage assets are ruxolitinib, targeting steroid-refractory chronic graft-versus-host disease (GVHD), and itacitinib, which is undergoing Phase II/III trials for newly diagnosed chronic GVHD. Pemigatinib is also being investigated for conditions such as bladder cancer, cholangiocarcinoma, myeloproliferative syndrome, and other tumor types.…

Earnings scorecard

Reported versus consensus
Reported EPS $1.81 Consensus $1
EPS surprise +35.1% Reported versus consensus
Reported revenue $1.27B Consensus $1.22B
Revenue surprise +4.7% Reported versus consensus

Earnings History

Estimate Beat Miss Match
INCY EPS earnings history estimate and actual scatter chart 9 reported fiscal quarters and 3 future estimate-only quarters. Q1 '24 estimate $0.84 Q1 '24 actual $0.64, miss Q2 '24 estimate $0.78 Q2 '24 actual $-1.82, miss Q3 '24 estimate $1.12 Q3 '24 actual $1.07, miss Q2 '25 estimate $1.39 Q2 '25 actual $1.57, beat Q3 '25 estimate $1.66 Q3 '25 actual $2.26, beat Q4 '25 estimate $1.90 Q4 '25 actual $1.80, miss Q1 '26 estimate $1.34 Q1 '26 actual $1.81, beat Q2 '26 estimate $2.15 Q2 '26 actual $3.09, beat Q3 '26 estimate $-1.59 Q4 '26 estimate $2.12 Q1 '27 estimate $1.79
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Analyst Consensus ?

ConsensusBuy44 ratings
Bullish2352.3%
Neutral2045.4%
Bearish12.3%

Analyst 52W Price Targets

$122.99Current
$48Low
$104.92Average
$200High

Latest persisted target per named analyst; persisted current price from FN2's market snapshot as of Jul 31, 2026. Not an FN2 forecast.

Firm-level rating actions

FMP grade actions identify the grading firm, not a named analyst.

FirmRatingPrior ratingActionDate
RBC Capital Sector Perform Sector PerformMaintainJul 29, 2026
HC Wainwright & Co. Buy BuyMaintainJul 29, 2026
Guggenheim Buy BuyMaintainJul 29, 2026
BMO Capital Market Perform Market PerformMaintainJul 29, 2026
Barclays Overweight OverweightMaintainJul 29, 2026
Morgan Stanley Equal Weight Equal WeightMaintainJul 23, 2026
JP Morgan Neutral NeutralMaintainJul 23, 2026
UBS Neutral NeutralMaintainJun 26, 2026
Truist Securities Hold HoldMaintainJun 22, 2026
Stifel Buy BuyMaintainApr 29, 2026
Oppenheimer Perform PerformMaintainApr 29, 2026
Jefferies Hold BuyDowngradeMar 16, 2026
Evercore ISI Group In Line In LineMaintainMar 5, 2026
Wells Fargo Equal Weight Equal WeightMaintainFeb 11, 2026
Piper Sandler Overweight OverweightMaintainFeb 6, 2026
TD Cowen Buy BuyMaintainJan 13, 2026
Mizuho Outperform NeutralUpgradeDec 8, 2025
B of A Securities Buy BuyMaintainSep 4, 2025
Citigroup Buy BuyMaintainJul 30, 2025
William Blair Market Perform OutperformDowngradeMar 18, 2025
Citizens Capital Markets Market Perform Market PerformMaintainMar 11, 2025
JMP Securities Market Perform Market PerformMaintainFeb 11, 2025
Cantor Fitzgerald Neutral NeutralMaintainJan 10, 2025
Goldman Sachs Neutral NeutralMaintainOct 30, 2024
Deutsche Bank Hold HoldMaintainAug 1, 2024
Leerink Partners Outperform Market PerformUpgradeDec 13, 2023
SVB Leerink Underperform UnderperformMaintainMar 20, 2023
Credit Suisse Buy BuyMaintainFeb 16, 2023
Cowen & Co. Outperform OutperformMaintainFeb 8, 2023
Benchmark Buy HoldUpgradeJul 20, 2021
Guggenheim Securities Neutral BuyDowngradeJan 2, 2020
Nomura Buy BuyMaintainJul 31, 2019
Stifel Nicolaus Hold HoldMaintainApr 11, 2019
Argus Research Buy BuyMaintainFeb 25, 2019
Argus Buy BuyMaintainFeb 25, 2019
Gabelli & Co. Buy HoldUpgradeJan 24, 2019
Leerink Swann Perform Market PerformMaintainSep 25, 2018
Raymond James Outperform Market PerformUpgradeSep 11, 2017
PiperJaffray Neutral OverweightDowngradeApr 17, 2017
SunTrust Robinson Humphrey Buy BuyMaintainAug 5, 2016
Brean Capital Buy BuyMaintainFeb 12, 2016
Bank of America Buy BuyMaintainMay 29, 2015
Lazard Buy NeutralUpgradeJan 14, 2013
Canaccord Genuity Buy BuyMaintainApr 26, 2012
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Named analyst price targets

Upside is calculated against the persisted current price $122.99. FMP does not supply a rating on these named-analyst rows.

FirmAnalyst52W targetPrice when postedUpsideDate
RBC CapitalBrian Abrahams$109$126.69 -11.4%Jul 29, 2026
BMO CapitalAnalyst unavailable$130$128.83 +5.7%Jul 29, 2026
GuggenheimWhitney Ljem$150$129.93 +22.0%Jul 29, 2026
Morgan StanleyAnalyst unavailable$119$129.93 -3.2%Jul 29, 2026
H.C. WainwrightAnalyst unavailable$150$129.93 +22.0%Jul 29, 2026
BarclaysAnalyst unavailable$139$129.93 +13.0%Jul 29, 2026
Stifel NicolausStephen Willey$145$130.08 +17.9%Jul 28, 2026
OppenheimerAnalyst unavailable$120$130.08 -2.4%Jul 28, 2026
Morgan StanleyAnalyst unavailable$104$116.12 -15.4%Jul 23, 2026
BarclaysAnalyst unavailable$134$114.23 +9.0%Jul 14, 2026
BMO CapitalAnalyst unavailable$112$115.04 -8.9%Jul 13, 2026
RBC CapitalAnalyst unavailable$99$115.62 -19.5%Jul 7, 2026
UBSAnalyst unavailable$113$107.53 -8.1%Jun 26, 2026
Truist FinancialAnalyst unavailable$105$103.21 -14.6%Jun 22, 2026
BMO CapitalEvan David Seigerman$94$98.22 -23.6%Jun 22, 2026
H.C. WainwrightMitchell Kapoor$140$103.23 +13.8%Jun 10, 2026
Stifel NicolausStephen Willey$123$103.07 +0.0%Jun 9, 2026
OppenheimerJay Olson$107$100.64 -13.0%Jun 8, 2026
BernsteinAnalyst unavailable$99$97.41 -19.5%May 21, 2026
OppenheimerAnalyst unavailable$90$97.74 -26.8%Apr 29, 2026
BarclaysAnalyst unavailable$117$101.16 -4.9%Feb 18, 2026
Morgan StanleyAnalyst unavailable$102$98.45 -17.1%Feb 11, 2026
Stifel NicolausStephen Willey$120$100.05 -2.4%Feb 11, 2026
Piper SandlerAllison Bratzel$110$102.76 -10.6%Feb 6, 2026
H.C. WainwrightAnalyst unavailable$135$102.6 +9.8%Feb 5, 2026
BarclaysAnalyst unavailable$116$100.92 -5.7%Feb 4, 2026
Wells FargoAnalyst unavailable$107$106.21 -13.0%Jan 20, 2026
Goldman SachsAnalyst unavailable$90$110.57 -26.8%Jan 8, 2026
Stifel NicolausStephen Willey$119$101.79 -3.2%Jan 5, 2026
Truist FinancialSrikripa Devarakonda$103$100.91 -16.3%Dec 24, 2025
Morgan StanleyAnalyst unavailable$92$96.46 -25.2%Dec 8, 2025
Wells FargoDerek Archila$116$102.52 -5.7%Dec 8, 2025
Mizuho SecuritiesSalim Syed$121$102.52 -1.6%Dec 8, 2025
BarclaysAnalyst unavailable$115$102.06 -6.5%Nov 24, 2025
Piper SandlerAllison Bratzel$102$102.35 -17.1%Nov 4, 2025
Truist FinancialAnalyst unavailable$93$90.35 -24.4%Oct 29, 2025
RBC CapitalAnalyst unavailable$84$91.65 -31.7%Oct 29, 2025
Wells FargoDerek Archila$97$92.02 -21.1%Oct 29, 2025
BarclaysPeter Lawson$101$91.65 -17.9%Oct 29, 2025
UBSAnalyst unavailable$68$77.55 -44.7%Jul 30, 2025
RBC CapitalAnalyst unavailable$67$67.26 -45.5%Jun 23, 2025
GuggenheimAnalyst unavailable$92$60 -25.2%Mar 18, 2025
Seaport GlobalAaron Kessler$200$73 +62.6%Oct 30, 2024
OppenheimerJay Olson$82$73.6 -33.3%Oct 30, 2024
CitigroupDavid Lebowitz$97$73.6 -21.1%Oct 30, 2024
JefferiesKelly Shi$84$73.6 -31.7%Oct 29, 2024
Bank of America SecuritiesTazeen Ahmad$90$73.6 -26.8%Oct 29, 2024
Wolfe ResearchAndy Chen$84$66.1 -31.7%Sep 30, 2024
Bank of America SecuritiesTazeen Ahmad$68$63.56 -44.7%Sep 16, 2024
Goldman SachsSalveen Richter$60$63.56 -51.2%Sep 16, 2024
CitigroupDavid Lebowitz$92$62.16 -25.2%Aug 18, 2024
RBC CapitalBrian Abrahams$66$65.7 -46.3%Jul 31, 2024
OppenheimerJay Olson$81$68.57 -34.1%Jul 26, 2024
BMO CapitalEvan Seigerman$48$60.87 -61.0%Jul 2, 2024
Deutsche BankJames Shin$55$58.2 -55.3%May 23, 2024
BMO CapitalEvan David Seigerman$52$52.05 -57.7%Apr 30, 2024
Argus ResearchJasper Hellweg$70$50.48 -43.1%Apr 25, 2024
Cowen & Co.Analyst unavailable$100$80.38 -18.7%Feb 8, 2023
Wells FargoAnalyst unavailable$75$79.74 -39.0%Jan 3, 2023
OppenheimerJay Olson$98$73.99 -20.3%Aug 15, 2022
Leerink PartnersAnalyst unavailable$63$81.36 -48.8%Jul 20, 2022
Morgan StanleyAnalyst unavailable$76$78.94 -38.2%Apr 20, 2022
BMO CapitalEvan Seigerman$75$70.07 -39.0%Feb 8, 2022
GuggenheimMichael Schmidt$104$73.97 -15.4%Jan 3, 2022
Goldman SachsSalveen Richter$136$66.74 +10.6%Nov 24, 2021
OppenheimerJay Olson$109$66.79 -11.4%Nov 3, 2021
Cantor FitzgeraldAlethia Young$79$65.56 -35.8%Oct 15, 2021
Ladenburg Thalmann & Co.Aydin Huseynov$89$69.78 -27.6%Sep 23, 2021
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Market reaction

prior-close to event-session close
Stock move +2.1% Event window
SPY move -0.5% Same window
Abnormal move +2.6% Stock minus SPY
Volume 1.9× Versus trailing sessions
Subsequent drift -0.4% Up to 20 sessions
INCYSPY benchmark

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Transcript intelligence

What changed

Compared to Q4 2025, which set full-year guidance and outlined 14 pivotal trials across 7 assets, Q1 2026 provided the first quarterly validation. Revenue of $1.27B beat the $1.22B consensus by 4.7%, and EPS of $1.81 exceeded the $1.34 estimate by 35%. The bullish score ticked up from 78 to 82. Several regulatory milestones moved from filing stage to acceptance: the FDA accepted the povorcitinib NDA for HS ahead of schedule, the European Commission approved Zynyz for anal carcinoma, and positive Phase III vitiligo data emerged for povorcitinib. New executive leadership, including a CFO, was added since the prior quarter.

Guidance delta

Full-year 2026 revenue guidance was reaffirmed at $4.77-$4.94 billion, implying 10-13% top-line growth, with non-Jakafi core sales tracking toward ~30% growth at the midpoint. Guidance sentiment was maintained from the prior quarter.

Key takeaways

  • Q1 revenue rose 21% to $1.27B, with net sales up 20% year-over-year, beating consensus on both the top and bottom lines
  • EPS of $1.81 exceeded the $1.34 estimate by 35%, reflecting operating leverage as revenue scaled ahead of expectations
  • Four new product launches are planned in 2026: Jakafi XR, Opzelura for moderate AD in Europe, Monjuvi in first-line DLBCL, and povorcitinib for hidradenitis suppurativa
  • FDA accepted the povorcitinib NDA for HS ahead of schedule, with approval and launch targeted for early 2027
  • Positive Phase III results for povorcitinib in non-segmental vitiligo support a 2027 filing
  • Executive team expanded with a new CFO and senior leaders to support the next phase of growth

Management priorities

  • Mid-year launch of Jakafi XR with a targeted formulary strategy
  • Second-half 2026 launch of Opzelura for moderate atopic dermatitis in Europe
  • Early 2027 launch of Monjuvi in first-line DLBCL
  • Povorcitinib FDA approval and launch for hidradenitis suppurativa in early 2027
  • Phase III data readouts for 989 (ET and MF), 734 (PDAC), A90 (colorectal), and CDK2 inhibitor 667

Related earnings events

Healthcare

Sources

  1. Earnings call transcript and parsed analysis · 2026-05-11T10:29:34.698584+00:00
  2. FN2 earnings calendar · 2026-07-26T00:37:12.209961+00:00
  3. Polygon adjusted daily market bars · 2026-07-30T21:21:58.368238+00:00
  4. Financial Modeling Prep analyst price-target consensus and quote snapshot · 2026-07-30T21:21:58.365500+00:00

Methodology

Reported and consensus figures come from FN2's earnings event records. Market reaction and volume are calculated from daily adjusted bars around the event; abnormal move subtracts the SPY move over the same window.

Analyst target low, average, and high values are derived at request time from each named analyst's latest persisted FMP target. The current-price marker comes from FN2's persisted market snapshot. They are sell-side estimates, not an FN2 valuation or recommendation.

Transcript intelligence is a structured synthesis of the current and prior earnings-call analyses. Missing values stay missing and are never estimated.

By FN2 Research · Updated . For educational purposes only; not investment advice.