Amgen Inc. · AMGN · FY2023 Q3 · Calendar Q4 2023

Amgen: Volume Growth and Horizon Integration Shape the Outlook

The supplied analysis supports a constructive but qualified view: resilient volume growth, Horizon's rare-disease portfolio, and pipeline investment strengthen the growth framework, while debt, pricing, integration, and execution risks temper the outlook.

Reported After market closeNASDAQHealthcare $229.74B market cap
100quality score

Earnings scorecard

Reported versus consensus
Reported EPS $4.71 Consensus $4.59
EPS surprise +2.6% Reported versus consensus
Reported revenue $8.20B Consensus $8.13B
Revenue surprise +0.9% Reported versus consensus

Market reaction

event-close to next-session close
Stock move -6.4% Event window
SPY move +0.8% Same window
Abnormal move -7.2% Stock minus SPY
Volume 3.2× Versus trailing sessions
Subsequent drift -7.8% Up to 20 sessions
AMGNSPY benchmark

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Transcript intelligence

What changed

Compared with the prior-quarter analysis, the company had closed the Horizon acquisition, reported continued double-digit volume growth, raised revenue guidance, and emphasized higher investment in manufacturing, R&D, and generative AI. The analysis also identifies higher interest expense and potential Horizon inventory effects as new or more prominent considerations.

Guidance delta

Revenue guidance was raised, while EPS guidance was narrowed; the analysis also points to higher R&D, capex, and interest expense.

Key takeaways

  • Management described double-digit global volume growth, with notable momentum in BLINCYTO and continued strength in Repatha and EVENITY.
  • The Horizon acquisition expanded rare diseases into a larger commercial pillar, while also increasing debt-related interest expense and integration considerations.
  • The company is investing in obesity research, new manufacturing capacity, and generative AI across discovery, clinical development, and commercial functions.

Management priorities

  • Integrate Horizon's rare-disease portfolio and expand its commercial reach.
  • Advance obesity, Lp(a), oncology, and other late-stage pipeline programs.
  • Build manufacturing capacity and deploy generative AI across research, clinical, and commercial work.

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Earnings History

Estimate Beat Miss Match
AMGN EPS earnings history estimate and actual scatter chart 9 reported fiscal quarters and 3 future estimate-only quarters. Q1 '24 estimate $3.88 Q1 '24 actual $3.96, beat Q2 '24 estimate $4.98 Q2 '24 actual $4.97, match Q3 '24 estimate $5.11 Q3 '24 actual $5.58, beat Q2 '25 estimate $5.28 Q2 '25 actual $6.02, beat Q3 '25 estimate $5.02 Q3 '25 actual $5.64, beat Q4 '25 estimate $4.73 Q4 '25 actual $5.29, beat Q1 '26 estimate $4.77 Q1 '26 actual $5.15, beat Q2 '26 estimate $5.62 Q2 '26 actual $6.29, beat Q3 '26 estimate $5.77 Q4 '26 estimate $5.77 Q1 '27 estimate $5.42
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Analyst Consensus ?

ConsensusHold41 ratings
Bullish2253.7%
Neutral1639.0%
Bearish37.3%

Analyst 52W Price Targets

$424.94Previous close
$182Low
$348.75Average
$500High

Latest persisted target per named analyst; persisted previous close from FN2's market snapshot as of Oct 20, 2026. Not an FN2 forecast.

Firm-level rating actions

FMP grade actions identify the grading firm, not a named analyst.

FirmRatingPrior ratingActionDate
Guggenheim Neutral NeutralMaintainOct 13, 2026
Wells Fargo Equal Weight Equal WeightMaintainOct 12, 2026
BMO Capital Market Perform Market PerformMaintainOct 12, 2026
UBS Buy BuyMaintainOct 9, 2026
RBC Capital Outperform OutperformMaintainOct 8, 2026
Show 36 more rating actions

Named analyst price targets

Upside is calculated against the persisted previous close $424.94. FMP does not supply a rating on these named-analyst rows.

FirmAnalyst52W targetPrice when postedUpsideDate
GuggenheimVamil Divan$378$417.57 -11.0%Oct 13, 2026
BMO CapitalAnalyst unavailable$415$415.8 -2.3%Oct 12, 2026
Wells FargoAnalyst unavailable$430$414.87 +1.2%Oct 12, 2026
RBC CapitalAnalyst unavailable$430$407.58 +1.2%Oct 8, 2026
Cantor FitzgeraldCarter Gould$440$413.08 +3.5%Oct 8, 2026
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Company context

Snapshot as of publication

Amgen Inc., established in 1980 and headquartered in Thousand Oaks, California, is a global biotechnology leader focused on discovering, developing, manufacturing, and delivering groundbreaking human medicines. The company's scientific endeavors span several critical therapeutic categories, including inflammatory conditions, oncology and hematology, bone health, cardiovascular diseases, nephrology, and neuroscience. Its extensive portfolio features a range of significant pharmaceutical products. Notable examples include Enbrel, prescribed for conditions like plaque psoriasis, rheumatoid arthritis, and psoriatic arthritis; Neulasta, which helps cancer patients by reducing the risk of infection linked to a low white blood cell count; Prolia, utilized in postmenopausal women to combat osteoporosis; and Xgeva, designed to prevent skeletal-related complications. Otezla offers relief for adult patients suffering from plaque psoriasis, psoriatic arthritis, and oral ulcers associated with Behçet's disease.…

Historical context

All AMGN earnings

Latest beats and misses

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Sources

  1. Earnings call transcript and parsed analysis · 2026-05-11T10:29:34.698584+00:00
  2. FN2 earnings calendar · 2024-11-11T06:39:45.180704+00:00
  3. Polygon adjusted daily market bars · 2026-10-20T12:40:45.156818+00:00
  4. Financial Modeling Prep analyst price-target consensus and quote snapshot · 2026-10-20T12:40:45.154932+00:00

Methodology

Reported and consensus figures come from FN2's earnings event records. Market reaction and volume are calculated from daily adjusted bars around the event; abnormal move subtracts the SPY move over the same window.

Analyst target low, average, and high values are derived at request time from each named analyst's latest persisted FMP target. The current-price marker comes from FN2's persisted market snapshot. They are sell-side estimates, not an FN2 valuation or recommendation.

Transcript intelligence is a structured synthesis of the current and prior earnings-call analyses. Missing values stay missing and are never estimated.

By FN2 Research · Updated · As of 2026-10-20. For educational purposes only; not investment advice.