Tempus AI, Inc. · TEM · FY2025 Q4 · Calendar Q1 2026

Tempus AI: Growth, AI and MRD Execution

The call analysis supports a growth case built on diagnostics expansion and data licensing, with management pointing to AI products and MRD as additional opportunities. The thesis remains execution-dependent: reimbursement, sales-force enablement, regulatory timing and competition could limit the expected contribution.

Reported After market closeNASDAQHealthcare $12.80B market cap
90quality score

Earnings scorecard

Reported versus consensus
Reported EPS $-0.04 Consensus $-0.04
EPS surprise +8.8% Reported versus consensus
Reported revenue $367.2M Consensus $362.6M
Revenue surprise +1.3% Reported versus consensus

Market reaction

event-close to next-session close
Stock move -7.3% Event window
SPY move +0.8% Same window
Abnormal move -8.2% Stock minus SPY
Volume 1.9× Versus trailing sessions
Subsequent drift -12.9% Up to 20 sessions
TEMSPY benchmark

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Transcript intelligence

What changed

Management described 2025 revenue growth above 33%, strength in diagnostics and data licensing, and a maintained 2026 outlook. The call highlighted progress on the AI foundation model and plans to expand assay offerings; MRD adoption and reimbursement remain open execution items. Prior-quarter analysis was unavailable, so a sequential narrative comparison cannot be established.

Guidance delta

Guidance was characterized as maintained. The call analysis reports 2026 revenue guidance of $1.59 billion and an expectation of positive adjusted EBITDA; no change to guidance was identified in the supplied analysis.

Key takeaways

  • The call analysis describes 2025 revenue growth above 33%, with diagnostics and data licensing both contributing.
  • Data licensing was described as having 126% net revenue retention, with projected growth of about 40% year over year.
  • Management highlighted AI foundation-model development and planned expansion of diagnostic assays.
  • MRD is a potential growth avenue, but scaling sales and reimbursement remain important execution dependencies.

Management priorities

  • Expand the AI foundation model across oncology and additional therapeutic areas.
  • Advance planned assay launches and regulatory steps, including xH, xE and xF.
  • Enable the MRD sales force and pursue broader adoption.
  • Grow data licensing and clinical-trial-matching services.

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Earnings History

Estimate Beat Miss Match
TEM EPS earnings history estimate and actual scatter chart 10 reported fiscal quarters and 4 future estimate-only quarters. Q2 '24 estimate $-0.59 Q2 '24 actual $-0.63, miss Q3 '24 estimate $-0.27 Q3 '24 actual $-0.25, beat Q2 '25 estimate $-0.23 Q2 '25 actual $-0.22, match Q3 '25 estimate $-0.17 Q3 '25 actual $-0.11, beat Q4 '25 estimate $-0.04 Q4 '25 actual $-0.04, match Q1 '26 estimate $-0.21 Q1 '26 actual $-0.13, beat Q2 '26 estimate $-0.14 Q2 '26 actual $-0.04, beat Q3 '26 estimate $-0.09 Q3 '26 actual $0.07, beat Q4 '26 estimate $-0.02 Q1 '27 estimate $-0.09 Q2 '27 estimate $-0.05 Q3 '27 estimate $-0.02
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Analyst Consensus ?

ConsensusBuy14 ratings
Bullish964.3%
Neutral535.7%
Bearish00.0%

Analyst 52W Price Targets

$78.48Current
$44Low
$75.74Average
$110High

Latest persisted target per named analyst; persisted current price from FN2's market snapshot as of Nov 3, 2026. Not an FN2 forecast.

Firm-level rating actions

FMP grade actions identify the grading firm, not a named analyst.

FirmRatingPrior ratingActionDate
Needham Buy BuyMaintainNov 2, 2026
HC Wainwright & Co. Buy BuyMaintainOct 26, 2026
BTIG Buy BuyMaintainOct 26, 2026
JP Morgan Neutral NeutralMaintainOct 14, 2026
Canaccord Genuity Buy BuyMaintainOct 12, 2026
Guggenheim Buy BuyMaintainOct 1, 2026
Piper Sandler Overweight NeutralUpgradeSep 1, 2026
Freedom Capital Markets Hold HoldMaintainAug 31, 2026
Stifel Hold HoldMaintainAug 3, 2026
TD Cowen Buy BuyMaintainMay 6, 2026
Morgan Stanley Overweight OverweightMaintainMar 3, 2026
B of A Securities Neutral NeutralMaintainJun 25, 2025
William Blair Market Perform OutperformDowngradeFeb 12, 2025
Loop Capital Buy BuyMaintainJan 14, 2025
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Named analyst price targets

Upside is calculated against the persisted current price $78.48. FMP does not supply a rating on these named-analyst rows.

FirmAnalyst52W targetPrice when postedUpsideDate
NeedhamRyan Macdonald$89$78.9 +13.4%Nov 2, 2026
H.C. WainwrightYi Chen$68$67.62 -13.4%Oct 26, 2026
GuggenheimSubbu Nambi$92$81.22 +17.2%Oct 1, 2026
Goldman SachsAnalyst unavailable$75$77.84 -4.4%Sep 21, 2026
H.C. WainwrightYi Chen$66$58.74 -15.9%Sep 11, 2026
UBSDouglas Schenkel$70$64.29 -10.8%Sep 9, 2026
Redburn PartnersJamie Clark$67$64.62 -14.6%Sep 8, 2026
Raymond JamesSarah James$80$62.27 +1.9%Sep 2, 2026
Cantor FitzgeraldAnalyst unavailable$80$62.27 +1.9%Sep 2, 2026
Piper SandlerAnalyst unavailable$76$63.05 -3.2%Sep 1, 2026
Piper SandlerAnalyst unavailable$56$46.05 -28.6%Aug 4, 2026
BTIGAnalyst unavailable$70$46.78 -10.8%Aug 3, 2026
H.C. WainwrightYi Chen$56$46.95 -28.6%Aug 3, 2026
Stifel NicolausAnalyst unavailable$50$43.87 -36.3%Aug 3, 2026
GuggenheimSubbu Nambi$65$57.25 -17.2%Jul 16, 2026
H.C. WainwrightYi Chen$64$49.86 -18.5%May 11, 2026
BTIGAnalyst unavailable$80$49.86 +1.9%May 10, 2026
H.C. WainwrightYi Chen$95$52.03 +21.0%Mar 10, 2026
Stifel NicolausDaniel Arias$60$53.83 -23.5%Feb 25, 2026
Mizuho SecuritiesBradley Bowers$100$56.16 +27.4%Feb 19, 2026
Robert W. BairdAnalyst unavailable$59$51.95 -24.8%Feb 17, 2026
Canaccord GenuityKyle Mikson$80$64.46 +1.9%Dec 22, 2025
Morgan StanleyAnalyst unavailable$85$74.07 +8.3%Dec 1, 2025
BTIGMark Massaro$105$76.06 +33.8%Nov 25, 2025
Canaccord GenuityKyle Mikson$95$84.49 +21.0%Nov 5, 2025
Piper SandlerAnalyst unavailable$105$89.1 +33.8%Oct 22, 2025
Canaccord GenuityAnalyst unavailable$110$87.78 +40.2%Oct 20, 2025
GuggenheimAnalyst unavailable$95$78.93 +21.0%Sep 26, 2025
H.C. WainwrightYi Chen$90$78.34 +14.7%Sep 2, 2025
NeedhamRyan MacDonald$70$58.74 -10.8%Aug 8, 2025
Morgan StanleyAnalyst unavailable$60$48.86 -23.5%Mar 6, 2025
Piper SandlerAnalyst unavailable$55$52.73 -29.9%Mar 4, 2025
Piper SandlerDavid Westenberg$70$44.94 -10.8%Nov 12, 2024
Stifel NicolausDaniel Arias$65$44.94 -17.2%Nov 11, 2024
NeedhamRyan Macdonald$56$44.94 -28.6%Nov 5, 2024
Loop Capital MarketsMark Schappel$57$50.72 -27.4%Oct 15, 2024
Bank of America SecuritiesMichael Ryskin$60$53.07 -23.5%Oct 2, 2024
Piper SandlerDavid Westenberg$40$38.75 -49.0%Aug 12, 2024
NeedhamRyan MacDonald$47$33.74 -40.1%Jul 9, 2024
Morgan StanleyTejas Savant$44$33.2 -43.9%Jul 9, 2024
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Company context

Snapshot as of publication

Tempus AI, Inc. operates as a healthcare technology company in the United States. It offers the Tempus platform, a closed-loop, full-stack, bi-directional integrations between a clinician's desktop and its laboratory diagnostic capabilities, analytics platform, and repository of multimodal data; and Hub, a clinical application for physicians and other healthcare providers for use in the diagnostics product line as an end-to-end application for healthcare providers for NGS tests. The company also provides Lens, a software application for life sciences and advanced precision research; diagnostics services, such as NGS diagnostics, PCR profiling, and other anatomic and molecular pathology tests; and large-panel solid tumor and hematologic testing through multiple assays, with its core clinical assay (xT and xR) offering large panel DNA, RNA full transcriptome, and incidental germline findings through normal blood or saliva analyses.…

Historical context

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Sources

  1. Earnings call transcript and parsed analysis · 2026-05-11T10:29:34.698584+00:00
  2. FN2 earnings calendar · 2026-07-26T00:37:12.209961+00:00
  3. Polygon adjusted daily market bars · 2026-11-03T00:30:44.469845+00:00
  4. Financial Modeling Prep analyst price-target consensus and quote snapshot · 2026-11-03T00:30:44.467043+00:00

Methodology

Reported and consensus figures come from FN2's earnings event records. Market reaction and volume are calculated from daily adjusted bars around the event; abnormal move subtracts the SPY move over the same window.

Analyst target low, average, and high values are derived at request time from each named analyst's latest persisted FMP target. The current-price marker comes from FN2's persisted market snapshot. They are sell-side estimates, not an FN2 valuation or recommendation.

Transcript intelligence is a structured synthesis of the current and prior earnings-call analyses. Missing values stay missing and are never estimated.

By FN2 Research · Updated · As of 2026-11-03. For educational purposes only; not investment advice.