Roivant Sciences Ltd. · ROIV · FY2025 Q4 · Calendar Q2 2026

Roivant advances pipeline as pivotal trials and readouts approach

The call’s investment case rests on converting encouraging pipeline evidence into validated later-stage outcomes and launches. Management pointed to progress across 1402, brepocitinib and mosliciguat, while the next tests include randomized or longer-term data, trial execution and regulatory decisions; the transcript analysis also cited the Moderna settlement as support for development and commercial preparation.

Why did ROIV rise 14.9% after beating EPS estimates in FY2025 Q4?

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Reported Before market openNASDAQHealthcare $28.08B market cap
100quality score

Earnings scorecard

Reported versus consensus
Reported EPS $-0.28 Consensus $-0.29
EPS surprise +3.5% Reported versus consensus
Reported revenue $2.5M Consensus $3.4M
Revenue surprise -26.2% Reported versus consensus
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Market reaction

prior-close to event-session close
Stock move +14.9% Event window
SPY move +1.0% Same window
Abnormal move +13.9% Stock minus SPY
Volume 3.0× Versus trailing sessions
Subsequent drift -3.0% Up to 20 sessions
ROIVSPY benchmark

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Transcript intelligence

What changed

Management described open-label 1402 responses in heavily refractory rheumatoid arthritis, brepocitinib’s breakthrough therapy designation for cutaneous sarcoidosis and progress toward its dermatomyositis launch, and mosliciguat’s advancement in PH-ILD studies. The call also highlighted the Moderna settlement. Compared with the prior-quarter analysis, this quarter’s analysis emphasizes newer program data and commercial preparation alongside plans for additional Phase III studies and second-half 2026 readouts.

Guidance delta

Guidance sentiment was classified as maintained in the supplied analysis. No changed formal financial guidance was identified there.

Key takeaways

  • The supplied analysis reports encouraging open-label 1402 responses in refractory rheumatoid arthritis, but randomized-withdrawal and longer-duration evidence remain important tests.
  • Brepocitinib received breakthrough therapy designation for cutaneous sarcoidosis; management discussed a planned dermatomyositis launch and Phase III work in additional indications.
  • Mosliciguat is progressing through Phase II evaluation for PH-ILD; the planned FOCUS study will assess pulmonary vascular resistance and six-minute-walk outcomes.
  • Management cited the Moderna settlement and cash resources as support for upcoming development and commercial preparation; future clinical and regulatory milestones remain uncertain.

Management priorities

  • Advance 1402 and brepocitinib clinical programs, including planned Phase III studies and additional readouts.
  • Continue mosliciguat’s Phase II FOCUS study and evaluate its pulmonary vascular resistance and six-minute-walk outcomes.
  • Prepare for brepocitinib commercialization through payer engagement and specialty-pharmacy partnerships.

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Earnings History

Estimate Beat Miss Match
ROIV REVENUE earnings history estimate and actual scatter chart 10 reported fiscal quarters and 4 future estimate-only quarters. Q2 '24 estimate $30M Q2 '24 actual $37M, beat Q3 '24 estimate $34M Q3 '24 actual $37M, beat Q4 '24 estimate $31M Q4 '24 actual $29M, miss Q1 '25 estimate $31M Q1 '25 actual $55M, beat Q1 '26 estimate $7M Q1 '26 actual $2M, miss Q2 '26 estimate $6M Q2 '26 actual $2M, miss Q3 '26 estimate $5M Q3 '26 actual $2M, miss Q4 '26 estimate $3M Q4 '26 actual $3M, miss Q1 '27 estimate $2M Q1 '27 actual $1M, miss Q2 '27 estimate $4M Q2 '27 actual $35M, beat Q3 '27 estimate $38M Q4 '27 estimate $66M Q1 '28 estimate $106M Q2 '28 estimate $136M
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Analyst Consensus ?

ConsensusBuy16 ratings
Bullish1487.5%
Neutral212.5%
Bearish00.0%

Analyst 52W Price Targets

$41.94Current
$10Low
$32.09Average
$55High

Latest persisted target per named analyst; persisted current price from FN2's market snapshot as of Nov 11, 2026. Not an FN2 forecast.

Firm-level rating actions

FMP grade actions identify the grading firm, not a named analyst.

FirmRatingPrior ratingActionDate
HC Wainwright & Co. Buy BuyMaintainNov 10, 2026
Citigroup Buy BuyMaintainOct 28, 2026
Wolfe Research Peer Perform OutperformDowngradeOct 12, 2026
TD Cowen Buy BuyMaintainSep 9, 2026
Guggenheim Buy BuyMaintainSep 9, 2026
Show 11 more rating actions

Named analyst price targets

Upside is calculated against the persisted current price $41.94. FMP does not supply a rating on these named-analyst rows.

FirmAnalyst52W targetPrice when postedUpsideDate
Stifel NicolausAnalyst unavailable$51$39.57 +21.6%Sep 16, 2026
GuggenheimYastin Suneja$46$41.48 +9.7%Sep 9, 2026
UBSAnalyst unavailable$55$41.48 +31.1%Sep 9, 2026
H.C. WainwrightAnalyst unavailable$47$42.03 +12.1%Sep 8, 2026
JefferiesAnalyst unavailable$52$41.7 +24.0%Sep 8, 2026
See 29 more

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Company context

Snapshot as of publication

Roivant Sciences Ltd. is a biopharmaceutical and healthcare technology company dedicated to discovering and advancing innovative therapeutic drugs. The firm's development pipeline targets a broad spectrum of diseases, including various forms of solid tumors and oncologic malignancies, hematological disorders like sickle cell disease and warm autoimmune hemolytic anemia, as well as rare conditions such as hypophosphatasia. Additionally, Roivant is developing treatments for immunological and dermatological ailments, including psoriasis, atopic dermatitis, vitiligo, hyperhidrosis, acne, myasthenia gravis, thyroid eye diseases, and sarcoidosis, alongside tackling infections like staph aureus bacteremia. Founded in 2014, its operations are based in London, United Kingdom.

Historical context

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Sources

  1. Earnings call transcript and parsed analysis · 2026-05-20T16:22:05.666044+00:00
  2. FN2 earnings calendar · 2026-07-26T00:37:12.209961+00:00
  3. Polygon adjusted daily market bars · 2026-11-09T22:50:44.871814+00:00
  4. Financial Modeling Prep analyst price-target consensus and quote snapshot · 2026-11-09T22:50:44.868859+00:00

Methodology

Reported and consensus figures come from FN2's earnings event records. Market reaction and volume are calculated from daily adjusted bars around the event; abnormal move subtracts the SPY move over the same window.

Analyst target low, average, and high values are derived at request time from each named analyst's latest persisted FMP target. The current-price marker comes from FN2's persisted market snapshot. They are sell-side estimates, not an FN2 valuation or recommendation.

Transcript intelligence is a structured synthesis of the current and prior earnings-call analyses. Missing values stay missing and are never estimated.

By FN2 Research · Updated · As of 2026-11-09. For educational purposes only; not investment advice.