Pfizer Inc. · PFE · FY2026 Q1 · Calendar Q2 2026

Pfizer Q1 2026: Revenue and EPS Beat, Guidance Reaffirmed, Pipeline Advances

Pfizer's Q1 2026 results show the post-COVID turnaround continuing to build momentum. Revenue of $14.5B and adjusted EPS of $0.75 both exceeded consensus, driven by 22% operational growth in the launched and acquired portfolio led by Padcev, Nurtec, Eliquis, and Vyndamax. Legal settlements extending Vyndamax exclusivity to mid-2029 and a Belgian court ruling on Comirnaty improve cash-flow visibility and support a high-single-digit CAGR starting 2029. Management reaffirmed full-year guidance and highlighted roughly 20 pivotal study starts, 8 key readouts, and 4 regulatory decisions planned for 2026. Despite the beat, the stock saw a modest negative abnormal return on report day and has drifted approximately 4.2% lower subsequently, suggesting the market remains cautious about LOE pressures through 2028 and the 2028 timeline for the first obesity approval.

Reported Before market openNYSEHealthcare $140.61B market cap
100quality score

Company context

Snapshot as of publication

Pfizer Inc. is a global biopharmaceutical leader engaged in the research, development, production, marketing, and distribution of a wide array of medicinal and vaccine products worldwide. Its comprehensive portfolio addresses diverse therapeutic areas, including cardiovascular health and women's health, featuring key brands such as the Premarin family and Eliquis. The company also offers advanced biologics, small molecule drugs, immunotherapies, and biosimilars for various conditions, exemplified by Ibrance, Xtandi, and Retacrit. Furthermore, Pfizer provides sterile injectables, anti-infective agents, and a significant oral treatment for COVID-19, including Paxlovid.…

Earnings scorecard

Reported versus consensus
Reported EPS $0.75 Consensus $1
EPS surprise +3.9% Reported versus consensus
Reported revenue $14.45B Consensus $13.84B
Revenue surprise +4.4% Reported versus consensus

Earnings History

Estimate Beat Miss Match
PFE EPS earnings history estimate and actual scatter chart 8 reported fiscal quarters and 4 future estimate-only quarters. Q4 '23 estimate $-0.19 Q4 '23 actual $0.10, beat Q1 '24 estimate $0.52 Q1 '24 actual $0.82, beat Q2 '24 estimate $0.46 Q2 '24 actual $0.60, beat Q3 '24 estimate $0.61 Q3 '24 actual $1.06, beat Q2 '25 estimate $0.58 Q2 '25 actual $0.78, beat Q3 '25 estimate $0.63 Q3 '25 actual $0.87, beat Q4 '25 estimate $0.57 Q4 '25 actual $0.66, beat Q1 '26 estimate $0.72 Q1 '26 actual $0.75, beat Q2 '26 estimate $0.68 Q3 '26 estimate $0.82 Q4 '26 estimate $0.70 Q1 '27 estimate $0.66

Analyst Consensus ?

ConsensusHold38 ratings
Bullish1436.9%
Neutral2360.5%
Bearish12.6%

1 unmapped firm rating excluded from the percentages.

Analyst 52W Price Targets

$25.25Current
$20Low
$39.24Average
$70High

Latest persisted target per named analyst; persisted current price from FN2's market snapshot as of Jul 29, 2026. Not an FN2 forecast.

Firm-level rating actions

FMP grade actions identify the grading firm, not a named analyst.

FirmRatingPrior ratingActionDate
Guggenheim Buy BuyMaintainJul 13, 2026
BMO Capital Outperform OutperformMaintainJul 13, 2026
B of A Securities Neutral NeutralMaintainJul 10, 2026
JP Morgan Neutral NeutralMaintainJul 8, 2026
HSBC Hold BuyDowngradeJul 6, 2026
Cantor Fitzgerald Neutral NeutralMaintainJul 6, 2026
RBC Capital Sector Perform UnderperformUpgradeJun 10, 2026
Citigroup Neutral NeutralMaintainApr 29, 2026
UBS Neutral NeutralMaintainApr 13, 2026
Morgan Stanley Equal Weight Equal WeightMaintainApr 10, 2026
Argus Research Buy HoldUpgradeMar 2, 2026
Freedom Broker Buy BuyMaintainFeb 9, 2026
Goldman Sachs Neutral BuyDowngradeApr 8, 2025
Truist Securities Buy BuyMaintainDec 18, 2024
Daiwa Capital Outperform NeutralUpgradeAug 8, 2024
Wells Fargo Equal Weight Equal WeightMaintainJul 31, 2024
Barclays Equal Weight Equal WeightMaintainJul 31, 2024
TD Cowen Market Perform OutperformDowngradeJan 4, 2024
Jefferies Buy HoldUpgradeOct 16, 2023
Credit Suisse Neutral OutperformDowngradeJun 29, 2023
SVB Leerink Market Perform Market PerformMaintainFeb 1, 2023
Atlantic Equities Neutral NeutralMaintainFeb 1, 2023
Mizuho Neutral NeutralMaintainDec 14, 2021
DZ Bank Buy HoldUpgradeFeb 4, 2021
Bernstein Perform Market PerformMaintainNov 10, 2020
Berenberg Hold HoldMaintainSep 29, 2020
Bank of America Neutral BuyDowngradeJul 30, 2019
Argus Outperform NeutralUpgradeJan 31, 2019
Leerink Swann Market Perform Market PerformMaintainJan 31, 2018
Societe Generale Hold HoldMaintainApr 6, 2016
SunTrust Robinson Humphrey Neutral NeutralMaintainFeb 16, 2016
Cowen & Co. Outperform Market PerformUpgradeOct 20, 2015
PiperJaffray Overweight OverweightMaintainJun 17, 2015
Deutsche Bank Buy BuyMaintainApr 28, 2015
LBBW Research Buy HoldUpgradeNov 14, 2013
Standpoint Research Sell HoldDowngradeJul 2, 2013
Hilliard Lyons Long Term Buy Long Term BuyMaintainJan 29, 2013
MKM Partners Neutral BuyDowngradeNov 27, 2012
ISI Group Buy BuyMaintainApr 9, 2012
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Named analyst price targets

Upside is calculated against the persisted current price $25.25. FMP does not supply a rating on these named-analyst rows.

FirmAnalyst52W targetPrice when postedUpsideDate
HSBCAnalyst unavailable$28$24.32 +10.9%Jul 6, 2026
UBSMichael Yee$27$26.34 +6.9%May 27, 2026
Wolfe ResearchAlexandria Hammond$26$25.96 +3.0%May 14, 2026
Morgan StanleyTerence Flynn$27$27.06 +6.9%Mar 17, 2026
BMO CapitalEvan David Seigerman$30$26.48 +18.8%Mar 9, 2026
RBC CapitalTrung Huynh$25$27.14 -1.0%Feb 24, 2026
BarclaysEmily Field$25$26.86 -1.0%Feb 19, 2026
DaiwaNarumi Nakagiri$27$27.73 +6.9%Feb 12, 2026
Cantor FitzgeraldAnalyst unavailable$27$25.88 +6.9%Jan 27, 2026
UBSAnalyst unavailable$25$25.43 -1.0%Jan 6, 2026
Wolfe ResearchAlexandria Hammond$24$25.53 -5.0%Dec 17, 2025
Morgan StanleyAnalyst unavailable$28$25.89 +10.9%Dec 12, 2025
HSBCRajesh Kumar$29$25.33 +14.9%Dec 10, 2025
GuggenheimAnalyst unavailable$35$25.17 +38.6%Nov 24, 2025
Goldman SachsAsad Haider$26$24.22 +3.0%Nov 5, 2025
BernsteinCourtney Breen$30$24.45 +18.8%Oct 31, 2025
Morgan StanleyAnalyst unavailable$32$25.24 +26.7%Oct 10, 2025
UBSTim Anderson$28$27.16 +10.9%Oct 1, 2025
Cantor FitzgeraldCarter Gould$24$22.53 -5.0%Apr 22, 2025
Truist FinancialRobyn Karnauskas$32$25.89 +26.7%Dec 18, 2024
Goldman SachsChris Shibutani$33$28.46 +30.7%Oct 30, 2024
BernsteinCourtney Breen$32$29.67 +26.7%Oct 17, 2024
BarclaysCarter Gould$32$28.93 +26.7%Sep 25, 2024
DaiwaNarumi Nakagiri$34$28.85 +34.7%Aug 7, 2024
Wells FargoMohit Bansal$30$31.39 +18.8%Jul 31, 2024
Goldman SachsChris Shibutani$34$31.39 +34.7%Jul 31, 2024
GuggenheimVamil Divan$36$30.72 +42.6%Jul 30, 2024
BarclaysCarter Gould$30$27.72 +18.8%Jul 10, 2024
BMO CapitalEvan Seigerman$36$29.6 +42.6%May 22, 2024
Cantor FitzgeraldLouise Chen$45$26.97 +78.2%Feb 14, 2024
Morgan StanleyThomas Yeh$20$26.92 -20.8%Dec 14, 2023
Morgan StanleyTerence Flynn$37$30.5 +46.5%Nov 27, 2023
Morgan StanleyAnalyst unavailable$45$43.84 +78.2%Feb 1, 2023
Credit SuisseAnalyst unavailable$50$43.59 +98.0%Feb 1, 2023
BarclaysAnalyst unavailable$44$44.16 +74.3%Feb 1, 2023
Atlantic EquitiesAnalyst unavailable$46$44.16 +82.2%Feb 1, 2023
Leerink PartnersAnalyst unavailable$48$44.16 +90.1%Feb 1, 2023
Morgan StanleyAnalyst unavailable$53$54.73 +109.9%Dec 14, 2022
Goldman SachsChris Shibutani$60$53.37 +137.6%Dec 13, 2022
Credit SuisseAnalyst unavailable$55$48.33 +117.8%Nov 18, 2022
Leerink PartnersDavid Risinger$55$52.88 +117.8%May 23, 2022
Wells FargoMohit Bansal$54.42$19.11 +115.5%May 10, 2022
Wells FargoMohit Bansal$55$49.04 +117.8%May 9, 2022
Morgan StanleyAnalyst unavailable$52$49.68 +105.9%May 4, 2022
Mizuho SecuritiesVamil Divan$55$49.07 +117.8%May 2, 2022
Cantor FitzgeraldLouise Chen$75$53.12 +197.0%Apr 15, 2022
Morgan StanleyTerrance Flynn$55$55.17 +117.8%Apr 10, 2022
CitigroupAndrew Baum$57$55.17 +125.7%Apr 9, 2022
Bank of America SecuritiesGeoff Meacham$70$50.27 +177.2%Mar 12, 2022
BarclaysCarter Gould$54$51.7 +113.9%Feb 8, 2022
Goldman SachsChris Shibutani$50$51.7 +98.0%Feb 8, 2022
J.P. MorganChris Schott$57$51.7 +125.7%Feb 8, 2022
BMO CapitalEvan Seigerman$76$54.95 +201.0%Jan 15, 2022
BernsteinAaron Gal$65$56.22 +157.4%Jan 3, 2022
Leerink PartnersGeoff Porges$56$59.1 +121.8%Dec 22, 2021
UBSColin Bristow$60$54.78 +137.6%Dec 13, 2021
Independent ResearchTobias Gottschalt$54$49.8 +113.9%Nov 11, 2021
Wolfe ResearchTim Anderson$46$44.09 +82.2%Nov 3, 2021
RBC CapitalDaniel Busby$44$42.1 +74.3%Jul 29, 2021
Argus ResearchDavid Toung$55$37.54 +117.8%Jun 1, 2021
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Market reaction

prior-close to event-session close
Stock move +0.6% Event window
SPY move +0.8% Same window
Abnormal move -0.2% Stock minus SPY
Volume 1.7× Versus trailing sessions
Subsequent drift -4.2% Up to 20 sessions
PFESPY benchmark

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Transcript intelligence

What changed

Revenue of $14.5B beat the $13.84B estimate by 4.4%; adjusted EPS of $0.75 beat the $0.722 estimate by 3.9%. The launched and acquired portfolio contributed $3.1B, growing 22% operationally. A Vyndamax patent settlement extends exclusivity to mid-2029, reshaping post-2028 revenue outlook. Phase III EV-304 data showed approximately 50% reduction in recurrence or death for muscle-invasive bladder cancer with Padcev plus pembrolizumab. Ecnoglutide launched in China via partnership with Hangzhou Sciwind Biosciences. A Belgian court ruling on Comirnaty contracts and the Vyndamax settlement both improve cash-flow outlook. Full-year 2026 guidance was reaffirmed at $59.5–62.5B revenue and $2.80–3.00 adjusted EPS.

Guidance delta

2026 guidance was reaffirmed at $59.5–62.5B revenue and $2.80–3.00 adjusted EPS, unchanged from the prior quarter's outlook. Management tone remained confident. The dividend was maintained. No changes to the capital allocation framework were announced.

Key takeaways

  • Q1 revenue of $14.5B and adjusted EPS of $0.75 both beat consensus, with the launched/acquired portfolio growing 22% operationally to $3.1B.
  • Vyndamax patent settlement extends exclusivity to mid-2029, improving post-2028 revenue trajectory and supporting a high-single-digit CAGR starting 2029.
  • Phase III EV-304 data showed approximately 50% reduction in recurrence or death for muscle-invasive bladder cancer with Padcev plus pembrolizumab.
  • Pipeline momentum includes roughly 20 pivotal study starts, 8 key readouts, and 4 regulatory decisions planned for 2026.
  • Full-year 2026 guidance reaffirmed at $59.5–62.5B revenue and $2.80–3.00 adjusted EPS; dividend maintained.

Management priorities

  • Advance 10 Phase III studies and target first obesity approval in 2028
  • Further integrate Seagen assets and expand the ADC oncology platform
  • Launch 25-valent pediatric pneumococcal vaccine and fifth-generation adult vaccine covering 35 serotypes
  • Deploy AI across R&D, commercial, manufacturing, and enterprise functions
  • Scale Metsera obesity portfolio globally, leveraging primary-care capabilities

Related earnings events

Healthcare

Sources

  1. Earnings call transcript and parsed analysis · 2026-05-11T10:29:34.698584+00:00
  2. FN2 earnings calendar · 2026-07-26T00:36:15.940040+00:00
  3. Polygon adjusted daily market bars · 2026-07-28T20:41:43.619399+00:00
  4. Financial Modeling Prep analyst price-target consensus and quote snapshot · 2026-07-28T20:41:43.616722+00:00

Methodology

Reported and consensus figures come from FN2's earnings event records. Market reaction and volume are calculated from daily adjusted bars around the event; abnormal move subtracts the SPY move over the same window.

Analyst target low, average, and high values are derived at request time from each named analyst's latest persisted FMP target. The current-price marker comes from FN2's persisted market snapshot. They are sell-side estimates, not an FN2 valuation or recommendation.

Transcript intelligence is a structured synthesis of the current and prior earnings-call analyses. Missing values stay missing and are never estimated.

By FN2 Research · Updated . For educational purposes only; not investment advice.