Pfizer Inc. · PFE · FY2025 Q1 · Calendar Q2 2025

Pfizer Maintains Guidance While Balancing Pipeline and Cost Pressures

The supplied analysis supports a conditional case for earnings resilience: cost discipline and pipeline progress may offset portfolio, tariff and policy pressures, but the evidence is incomplete because actual EPS and revenue are not supplied.

Reported Before market openNYSEHealthcare $167.80B market cap
80quality score

Earnings scorecard

Reported versus consensus
Reported EPS — Consensus $0.67
EPS surprise — Reported versus consensus
Reported revenue — Consensus $14.26B
Revenue surprise — Reported versus consensus

Market reaction

prior-close to event-session close
Stock move +3.2% Event window
SPY move +0.6% Same window
Abnormal move +2.6% Stock minus SPY
Volume 1.8× Versus trailing sessions
Subsequent drift -2.6% Up to 20 sessions
PFESPY benchmark

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Transcript intelligence

What changed

The current analysis highlights continued cost savings, multiple pipeline milestones, new ADC and vaccine work, and a discontinued program following a potential liver-injury signal. Management's guidance sentiment remained maintained.

Guidance delta

Management maintained FY2025 revenue and adjusted EPS guidance.

Key takeaways

  • Management emphasized R&D productivity, oncology and obesity pipeline milestones, and new ADC programs.
  • Cost-improvement initiatives and margin discipline remain central to the near-term plan.
  • Tariffs, Medicare Part D redesign, loss of exclusivity and uncertain COVID-19 demand remain material risks.

Management priorities

  • Advance ADC, obesity and vaccine programs through upcoming clinical and regulatory milestones.
  • Continue cost-saving efforts and commercial execution across core brands.
  • Manage tariff exposure, IRA-related pressure and the portfolio transition ahead of loss-of-exclusivity events.

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Earnings History

Estimate Beat Miss Match
PFE EPS earnings history estimate and actual scatter chart 9 reported fiscal quarters and 3 future estimate-only quarters. Q4 '23 estimate $-0.19 Q4 '23 actual $0.10, beat Q1 '24 estimate $0.52 Q1 '24 actual $0.82, beat Q2 '24 estimate $0.46 Q2 '24 actual $0.60, beat Q3 '24 estimate $0.61 Q3 '24 actual $1.06, beat Q2 '25 estimate $0.58 Q2 '25 actual $0.78, beat Q3 '25 estimate $0.63 Q3 '25 actual $0.87, beat Q4 '25 estimate $0.57 Q4 '25 actual $0.66, beat Q1 '26 estimate $0.72 Q1 '26 actual $0.75, beat Q2 '26 estimate $0.68 Q2 '26 actual $0.77, beat Q3 '26 estimate $0.73 Q4 '26 estimate $0.70 Q1 '27 estimate $0.66
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Analyst Consensus ?

ConsensusHold39 ratings
Bullish1538.4%
Neutral2359.0%
Bearish12.6%

1 unmapped firm rating excluded from the percentages.

Analyst 52W Price Targets

$29.57Current
$20Low
$39.14Average
$70High

Latest persisted target per named analyst; persisted current price from FN2's market snapshot as of Oct 16, 2026. Not an FN2 forecast.

Firm-level rating actions

FMP grade actions identify the grading firm, not a named analyst.

FirmRatingPrior ratingActionDate
JP Morgan Neutral NeutralMaintainOct 9, 2026
Cantor Fitzgerald Neutral NeutralMaintainOct 8, 2026
Scotiabank Sector Outperform Sector OutperformMaintainOct 6, 2026
HSBC Hold HoldMaintainSep 10, 2026
Guggenheim Buy BuyMaintainAug 7, 2026
Show 35 more rating actions

Named analyst price targets

Upside is calculated against the persisted current price $29.56. FMP does not supply a rating on these named-analyst rows.

FirmAnalyst52W targetPrice when postedUpsideDate
Cantor FitzgeraldCarter Gould$28$28 -5.3%Oct 8, 2026
ScotiabankAnalyst unavailable$33$27.3 +11.6%Oct 6, 2026
HSBCAnalyst unavailable$30$27.78 +1.5%Sep 10, 2026
GuggenheimAnalyst unavailable$31$26.2 +4.9%Aug 7, 2026
HSBCAnalyst unavailable$28$24.32 -5.3%Jul 6, 2026
See 59 more

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Company context

Snapshot as of publication

Pfizer Inc. is a global biopharmaceutical leader engaged in the research, development, production, marketing, and distribution of a wide array of medicinal and vaccine products worldwide. Its comprehensive portfolio addresses diverse therapeutic areas, including cardiovascular health and women's health, featuring key brands such as the Premarin family and Eliquis. The company also offers advanced biologics, small molecule drugs, immunotherapies, and biosimilars for various conditions, exemplified by Ibrance, Xtandi, and Retacrit. Furthermore, Pfizer provides sterile injectables, anti-infective agents, and a significant oral treatment for COVID-19, including Paxlovid.…

Historical context

All PFE earnings

Latest beats and misses

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Sources

  1. Earnings call transcript and parsed analysis · 2026-05-11T10:29:34.698584+00:00
  2. FN2 earnings calendar · 2025-04-15T00:03:42.498162+00:00
  3. Polygon adjusted daily market bars · 2026-10-16T13:50:47.804730+00:00
  4. Financial Modeling Prep analyst price-target consensus and quote snapshot · 2026-10-16T13:50:47.801907+00:00

Methodology

Reported and consensus figures come from FN2's earnings event records. Market reaction and volume are calculated from daily adjusted bars around the event; abnormal move subtracts the SPY move over the same window.

Analyst target low, average, and high values are derived at request time from each named analyst's latest persisted FMP target. The current-price marker comes from FN2's persisted market snapshot. They are sell-side estimates, not an FN2 valuation or recommendation.

Transcript intelligence is a structured synthesis of the current and prior earnings-call analyses. Missing values stay missing and are never estimated.

By FN2 Research · Updated · As of 2026-10-16. For educational purposes only; not investment advice.