Merck & Co., Inc. · MRK · FY2026 Q3 · Calendar Q4 2026

Merck Q3: Guidance Raised as Pipeline Progress Continues

The quarter strengthens the case that Merck can extend growth through launches, pipeline milestones and animal-health performance, but the thesis depends on execution before and after KEYTRUDA loss-of-exclusivity.

Reported Before market openNYSEHealthcare $361.02B market cap
100quality score

Earnings scorecard

Reported versus consensus
Reported EPS $2.49 Consensus $2.09
EPS surprise +19.1% Reported versus consensus
Reported revenue $18.09B Consensus $17.33B
Revenue surprise +4.4% Reported versus consensus

Market reaction

prior-close to event-session close
Stock move +3.8% Event window
SPY move -0.4% Same window
Abnormal move +4.2% Stock minus SPY
Volume 1.4× Versus trailing sessions
Subsequent drift 0.0% Up to 20 sessions
MRKSPY benchmark

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Transcript intelligence

What changed

Compared with the prior quarter, Merck delivered Q3 revenue growth, raised FY2026 revenue and EPS guidance, and added further clinical and regulatory progress. The main new offsets are the disclosed timing-benefit unwind, ongoing QLEX litigation and greater focus on the KEYTRUDA loss-of-exclusivity transition.

Guidance delta

Management raised FY2026 revenue guidance to $66.8-$67.3 billion and EPS guidance to $2.77-$2.82.

Key takeaways

  • Q3 revenue was $18.1 billion, up 5% year over year, led by KEYTRUDA and animal health.
  • Management highlighted positive late-stage results for sac-TMT in endometrial cancer and the entismodigene vaccine in melanoma.
  • New regulatory milestones included subcutaneous pembrolizumab approvals in Japan and China.
  • The growth plan relies on new launches, pipeline readouts and portfolio expansion ahead of KEYTRUDA loss-of-exclusivity.

Management priorities

  • Advance sac-TMT, WINREVAIR, tultokibart and remygrimeg through planned clinical and regulatory milestones.
  • Pursue regulatory submissions and indication expansion for oncology and vaccine programs.
  • Maintain R&D investment and share repurchases while preparing for KEYTRUDA loss-of-exclusivity.

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Earnings History

Estimate Beat Miss Match
MRK EPS earnings history estimate and actual scatter chart 10 reported fiscal quarters and 2 future estimate-only quarters. Q4 '23 estimate $-0.09 Q4 '23 actual $0.03, beat Q1 '24 estimate $1.88 Q1 '24 actual $2.07, beat Q2 '24 estimate $2.15 Q2 '24 actual $2.28, beat Q3 '24 estimate $1.50 Q3 '24 actual $1.57, beat Q2 '25 estimate $2.03 Q2 '25 actual $2.13, beat Q3 '25 estimate $2.36 Q3 '25 actual $2.58, beat Q4 '25 estimate $2.01 Q4 '25 actual $2.04, beat Q1 '26 estimate $-1.47 Q1 '26 actual $-1.28, beat Q2 '26 estimate $-0.27 Q2 '26 actual $-0.13, beat Q3 '26 estimate $2.09 Q3 '26 actual $2.49, beat Q4 '26 estimate $1.96 Q1 '27 estimate $2.21
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Analyst Consensus ?

ConsensusBuy38 ratings
Bullish2668.4%
Neutral1129.0%
Bearish12.6%

Analyst 52W Price Targets

$146.33Current
$80Low
$138.69Average
$180High

Latest persisted target per named analyst; persisted current price from FN2's market snapshot as of Oct 30, 2026. Not an FN2 forecast.

Firm-level rating actions

FMP grade actions identify the grading firm, not a named analyst.

FirmRatingPrior ratingActionDate
Barclays Overweight OverweightMaintainOct 26, 2026
RBC Capital Sector Perform Sector PerformMaintainOct 12, 2026
Citigroup Neutral NeutralMaintainOct 12, 2026
Cantor Fitzgerald Neutral NeutralMaintainOct 8, 2026
Morgan Stanley Overweight OverweightMaintainOct 7, 2026
Show 33 more rating actions

Named analyst price targets

Upside is calculated against the persisted current price $146.33. FMP does not supply a rating on these named-analyst rows.

FirmAnalyst52W targetPrice when postedUpsideDate
BarclaysAnalyst unavailable$180$145.27 +23.0%Oct 26, 2026
Wells FargoAnalyst unavailable$165$147.24 +12.8%Oct 22, 2026
Goldman SachsAnalyst unavailable$155$146.26 +5.9%Oct 19, 2026
RBC CapitalTrung Huynh$145$145.6 -0.9%Oct 12, 2026
Cantor FitzgeraldCarter Gould$145$142.79 -0.9%Oct 8, 2026
See 90 more

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Company context

Snapshot as of publication

Merck & Co., Inc. is a global healthcare leader with operations spanning two core divisions: Pharmaceuticals and Animal Health. The Pharmaceutical segment is dedicated to human health, offering a broad spectrum of medicinal products. These cover crucial therapeutic areas such as oncology, acute hospital care, immunology, neuroscience, virology, cardiovascular conditions, and diabetes. This division also develops vital preventive vaccines for pediatric, adolescent, and adult populations. Meanwhile, the Animal Health segment focuses on the research, development, manufacturing, and marketing of veterinary medications, vaccines, and comprehensive health management solutions for animals. This division further provides innovative digital products designed for animal identification, traceability, and continuous monitoring.…

Historical context

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Sources

  1. Earnings call transcript and parsed analysis · 2026-10-29T18:12:31.555779+00:00
  2. FN2 earnings calendar · 2026-10-30T01:23:13.979536+00:00
  3. Polygon adjusted daily market bars · 2026-10-30T01:50:45.834287+00:00
  4. Financial Modeling Prep analyst price-target consensus and quote snapshot · 2026-10-30T01:50:45.831615+00:00

Methodology

Reported and consensus figures come from FN2's earnings event records. Market reaction and volume are calculated from daily adjusted bars around the event; abnormal move subtracts the SPY move over the same window.

Analyst target low, average, and high values are derived at request time from each named analyst's latest persisted FMP target. The current-price marker comes from FN2's persisted market snapshot. They are sell-side estimates, not an FN2 valuation or recommendation.

Transcript intelligence is a structured synthesis of the current and prior earnings-call analyses. Missing values stay missing and are never estimated.

By FN2 Research · Updated · As of 2026-10-30. For educational purposes only; not investment advice.