Medpace Holdings, Inc. · MEDP · FY2025 Q4 · Calendar Q1 2026

Medpace sustains growth, but cancellations and mix pressure remain key tests

The evidence supports a durable-demand case through strong oncology and metabolic activity, backlog conversion, and productivity gains, but it is conditional: cancellations, pass-through mix, hiring execution, competition, and uncertain AI returns are material offsets.

Reported After market closeNASDAQHealthcare $18.25B market cap
100quality score

Earnings scorecard

Reported versus consensus
Reported EPS $4.67 Consensus $4.19
EPS surprise +11.5% Reported versus consensus
Reported revenue $708.5M Consensus $689.3M
Revenue surprise +2.8% Reported versus consensus

Market reaction

event-close to next-session close
Stock move -15.9% Event window
SPY move -0.3% Same window
Abnormal move -15.6% Stock minus SPY
Volume 3.5× Versus trailing sessions
Subsequent drift +7.1% Up to 20 sessions
MEDPSPY benchmark

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Transcript intelligence

What changed

Compared with the prior quarter, the discussion shifted from record bookings and backlog momentum toward elevated cancellations, mix-driven margin pressure, and the execution of hiring and initial AI deployment. Management still described demand and the longer-term growth path positively.

Guidance delta

Management maintained its outlook while emphasizing normalization of pass-through mix, continued hiring, and gradual benefits from AI-enabled efficiency tools.

Key takeaways

  • Growth remained strong, led by oncology and continued metabolic-program demand, while improved retention supported productivity.
  • The main change was a sharp Q4 cancellation increase in metabolic work alongside a lower-margin reimbursable mix; management expects neither issue to become a lasting trend.

Management priorities

  • Accelerate hiring while protecting productivity and retention.
  • Deploy AI applications for feasibility analytics and efficiency, and normalize the revenue mix away from high-pass-through projects.

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Earnings History

Estimate Beat Miss Match
MEDP EPS earnings history estimate and actual scatter chart 10 reported fiscal quarters and 4 future estimate-only quarters. Q4 '23 estimate $2.22 Q4 '23 actual $2.46, beat Q1 '24 estimate $2.47 Q1 '24 actual $3.20, beat Q2 '24 estimate $2.54 Q2 '24 actual $2.75, beat Q3 '24 estimate $2.78 Q3 '24 actual $3.01, beat Q2 '25 estimate $2.98 Q2 '25 actual $3.10, beat Q3 '25 estimate $3.53 Q3 '25 actual $3.86, beat Q4 '25 estimate $4.19 Q4 '25 actual $4.67, beat Q1 '26 estimate $3.92 Q1 '26 actual $4.28, beat Q2 '26 estimate $3.98 Q2 '26 actual $4.25, beat Q3 '26 estimate $4.44 Q3 '26 actual $4.84, beat Q4 '26 estimate $4.65 Q1 '27 estimate $4.62 Q2 '27 estimate $4.67 Q3 '27 estimate $4.89
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Analyst Consensus ?

ConsensusHold17 ratings
Bullish423.5%
Neutral1376.5%
Bearish00.0%

1 unmapped firm rating excluded from the percentages.

Analyst 52W Price Targets

$669.2Current
$330Low
$565.12Average
$700High

Latest persisted target per named analyst; persisted current price from FN2's market snapshot as of Oct 24, 2026. Not an FN2 forecast.

Firm-level rating actions

FMP grade actions identify the grading firm, not a named analyst.

FirmRatingPrior ratingActionDate
Mizuho Outperform OutperformMaintainOct 7, 2026
Barclays Equal Weight Equal WeightMaintainOct 7, 2026
UBS Neutral SellUpgradeSep 30, 2026
Truist Securities Hold HoldMaintainJul 24, 2026
TD Cowen Hold HoldMaintainJul 24, 2026
Show 13 more rating actions

Named analyst price targets

Upside is calculated against the persisted current price $669.2. FMP does not supply a rating on these named-analyst rows.

FirmAnalyst52W targetPrice when postedUpsideDate
Mizuho SecuritiesAnalyst unavailable$700$602.9 +4.6%Oct 7, 2026
BarclaysAnalyst unavailable$625$602.9 -6.6%Oct 7, 2026
UBSAnalyst unavailable$673$622.11 +0.6%Sep 30, 2026
RBC CapitalRyan Halsted$692$601.73 +3.4%Jul 24, 2026
Mizuho SecuritiesAnalyst unavailable$665$605.82 -0.6%Jul 24, 2026
See 34 more

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Company context

Snapshot as of publication

Medpace Holdings, Inc., founded in Cincinnati, Ohio, in 1992, functions as a contract research organization (CRO) delivering clinical development and research services. The company assists pharmaceutical, biotechnology, and medical device clients throughout North America, Europe, and Asia. Its comprehensive suite of offerings covers the entire product lifecycle, from initial Phase I trials through to Phase IV post-market surveillance. Medpace's services include designing development programs, coordinating central laboratory functions, managing projects, navigating regulatory processes, overseeing clinical trials, handling data management and analytics, ensuring pharmacovigilance, aiding with new drug application submissions, and providing ongoing post-marketing clinical support. Furthermore, the company offers specialized bio-analytical laboratory testing, conducts clinical human pharmacology studies, provides imaging services, and delivers expert electrocardiography (ECG) reading for clinical research.

Historical context

All MEDP earnings

Healthcare peers this season

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Latest beats and misses

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Sources

  1. Earnings call transcript and parsed analysis · 2026-05-11T10:29:34.698584+00:00
  2. FN2 earnings calendar · 2026-07-26T00:37:12.209961+00:00
  3. Polygon adjusted daily market bars · 2026-10-24T00:30:43.930957+00:00
  4. Financial Modeling Prep analyst price-target consensus and quote snapshot · 2026-10-24T00:30:43.928242+00:00

Methodology

Reported and consensus figures come from FN2's earnings event records. Market reaction and volume are calculated from daily adjusted bars around the event; abnormal move subtracts the SPY move over the same window.

Analyst target low, average, and high values are derived at request time from each named analyst's latest persisted FMP target. The current-price marker comes from FN2's persisted market snapshot. They are sell-side estimates, not an FN2 valuation or recommendation.

Transcript intelligence is a structured synthesis of the current and prior earnings-call analyses. Missing values stay missing and are never estimated.

By FN2 Research · Updated · As of 2026-10-24. For educational purposes only; not investment advice.