Illumina, Inc. · ILMN · FY2026 Q2 · Calendar Q3 2026

Illumina Q2 2026: Clinical Growth Supports a Guidance Raise

The current evidence supports a constructive operating trajectory: clinical sequencing demand, NovaSeq X adoption and emerging multi-omics and data services are supporting growth and a raised outlook. The main counterweights are weak research markets, cost inflation and execution risk during the platform transition.

Reported After market closeNASDAQHealthcare $35.63B market cap
100quality score

Earnings scorecard

Reported versus consensus
Reported EPS $1.31 Consensus $1.23
EPS surprise +6.5% Reported versus consensus
Reported revenue $1.16B Consensus $1.13B
Revenue surprise +2.5% Reported versus consensus

Market reaction

event-close to next-session close
Stock move +0.0% Event window
SPY move +0.7% Same window
Abnormal move -0.7% Stock minus SPY
Volume 2.3× Versus trailing sessions
Subsequent drift +5.1% Up to 20 sessions
ILMNSPY benchmark

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What changed

Compared with the prior quarter, clinical consumables growth remained the central driver and NovaSeq X placements increased to more than 95. Illumina added early revenue from StrataMap, expanded BioInsight offerings and the Billion Cell Atlas, while raising full-year guidance; cost pressure and research-market weakness remain.

Guidance delta

Management raised full-year 2026 revenue and EPS guidance and expects Rest of World organic growth above 5%.

Key takeaways

  • Revenue increased 9.5% year over year to $1.16 billion, while non-GAAP EPS was $1.31; both beat guidance.
  • NovaSeq X placements exceeded 95 units, supporting future consumables pull-through.
  • Clinical consumables grew at a mid-teens rate and remained the primary growth engine.
  • New multi-omics and data offerings began contributing revenue, while research markets remained under pressure.

Management priorities

  • Expand the NovaSeq X installed base and clinical sequencing applications
  • Scale multi-omics workflows, including StrataMap and SomaLogic/SomaSeq
  • Develop BioInsight and Billion Cell Atlas data services and add pharmaceutical partners

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Earnings History

Estimate Beat Miss Match
ILMN EPS earnings history estimate and actual scatter chart 11 reported fiscal quarters and 4 future estimate-only quarters. Q3 '24 estimate $0.87 Q3 '24 actual $1.14, beat Q4 '24 estimate $0.92 Q4 '24 actual $0.91, match Q2 '25 estimate $1.02 Q2 '25 actual $1.19, beat Q3 '25 estimate $1.17 Q3 '25 actual $1.34, beat Q4 '25 estimate $1.24 Q4 '25 actual $1.35, beat Q1 '26 estimate $1.05 Q1 '26 actual $1.15, beat Q2 '26 estimate $1.23 Q2 '26 actual $1.31, beat Q3 '26 estimate $1.36 Q3 '26 actual $1.62, beat Q4 '26 estimate $1.53 Q1 '27 estimate $1.33 Q2 '27 estimate $1.48 Q3 '27 estimate $1.58
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Analyst Consensus ?

ConsensusHold50 ratings
Bullish2754.0%
Neutral1734.0%
Bearish612.0%

Analyst 52W Price Targets

$235.99Current
$100Low
$216.54Average
$562High

Latest persisted target per named analyst; persisted current price from FN2's market snapshot as of Oct 31, 2026. Not an FN2 forecast.

Firm-level rating actions

FMP grade actions identify the grading firm, not a named analyst.

FirmRatingPrior ratingActionDate
Evercore ISI Group Outperform OutperformMaintainOct 30, 2026
Canaccord Genuity Hold HoldMaintainOct 19, 2026
TD Cowen Hold HoldMaintainOct 13, 2026
Barclays Underweight UnderweightMaintainOct 7, 2026
RBC Capital Outperform OutperformMaintainOct 5, 2026
Guggenheim Buy BuyMaintainOct 1, 2026
Leerink Partners Outperform OutperformMaintainSep 29, 2026
Piper Sandler Overweight OverweightMaintainSep 28, 2026
UBS Buy NeutralUpgradeSep 9, 2026
Argus Research Buy BuyMaintainSep 3, 2026
Citigroup Sell SellMaintainAug 3, 2026
Stifel Buy BuyMaintainJul 31, 2026
JP Morgan Overweight OverweightMaintainJul 31, 2026
Baird Neutral NeutralMaintainOct 31, 2025
Morgan Stanley Equal Weight Equal WeightMaintainAug 4, 2025
Scotiabank Sector Perform Sector OutperformDowngradeJul 11, 2025
Stephens & Co. Overweight OverweightMaintainMay 20, 2025
HSBC Buy HoldUpgradeOct 17, 2024
Daiwa Capital Buy NeutralUpgradeAug 16, 2024
OTR Global Mixed PositiveDowngradeMar 20, 2024
B of A Securities Underperform NeutralDowngradeDec 12, 2023
Credit Suisse Neutral NeutralMaintainAug 10, 2023
SVB Leerink Outperform OutperformMaintainFeb 8, 2023
Wells Fargo Underweight UnderweightMaintainApr 28, 2021
Atlantic Equities Neutral OverweightDowngradeMar 31, 2021
BTIG Buy BuyMaintainFeb 16, 2021
Cowen & Co. Outperform OutperformMaintainDec 18, 2019
Piper Jaffray Overweight OverweightMaintainOct 25, 2019
Deutsche Bank Hold HoldMaintainJul 12, 2019
Bank of America Underperform BuyDowngradeJul 12, 2019
Argus Buy BuyMaintainAug 10, 2018
PiperJaffray Overweight OverweightMaintainJul 17, 2018
Leerink Swann Outperform OutperformMaintainJan 31, 2018
First Analysis Overweight Equal WeightUpgradeJan 31, 2018
William Blair Market Perform OutperformDowngradeJan 5, 2018
Janney Montgomery Scott Neutral SellUpgradeOct 23, 2017
Janney Capital Neutral SellUpgradeOct 23, 2017
CL King Neutral BuyDowngradeAug 22, 2016
Nomura Buy BuyMaintainMay 3, 2016
Cantor Fitzgerald Hold BuyDowngradeApr 19, 2016
Mizuho Neutral BuyDowngradeOct 6, 2015
Tigress Financial Strong Buy BuyUpgradeApr 23, 2015
Stifel Nicolaus Buy BuyMaintainOct 27, 2014
Wedbush Outperform NeutralUpgradeAug 20, 2014
Macquarie Outperform OutperformMaintainJul 24, 2014
Maxim Group Buy HoldUpgradeApr 23, 2014
JMP Securities Market Outperform Market OutperformMaintainMar 5, 2014
ISI Group Neutral NeutralMaintainJan 29, 2013
Goldman Sachs Neutral NeutralMaintainOct 24, 2012
CLSA Underperform OutperformDowngradeOct 24, 2012
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Named analyst price targets

Upside is calculated against the persisted current price $235.99. FMP does not supply a rating on these named-analyst rows.

FirmAnalyst52W targetPrice when postedUpsideDate
StephensAnalyst unavailable$275$268 +16.5%Oct 23, 2026
Canaccord GenuityAnalyst unavailable$300$262.54 +27.1%Oct 19, 2026
BarclaysAnalyst unavailable$200$273.54 -15.3%Oct 7, 2026
GuggenheimSubbu Nambi$305$270.81 +29.2%Oct 1, 2026
Leerink PartnersAnalyst unavailable$300$273.63 +27.1%Sep 29, 2026
Piper SandlerDavid Westenberg$305$270 +29.2%Sep 28, 2026
UBSAnalyst unavailable$260$211.06 +10.2%Sep 9, 2026
Argus ResearchAnalyst unavailable$235$213.25 -0.4%Sep 3, 2026
Canaccord GenuityAnalyst unavailable$205$205.1 -13.1%Aug 3, 2026
RBC CapitalAnalyst unavailable$230$199.13 -2.5%Jul 31, 2026
BernsteinAnalyst unavailable$215$205.09 -8.9%Jul 31, 2026
GuggenheimAnalyst unavailable$226$205.09 -4.2%Jul 31, 2026
BarclaysAnalyst unavailable$160$205.09 -32.2%Jul 31, 2026
Leerink PartnersPuneet Souda$210$186.89 -11.0%Jul 17, 2026
Canaccord GenuityKyle Mikson$190$190.05 -19.5%Jul 14, 2026
GuggenheimAnalyst unavailable$200$176.55 -15.3%Jun 29, 2026
BernsteinAnalyst unavailable$185$177.65 -21.6%Jun 26, 2026
GuggenheimAnalyst unavailable$180$162.96 -23.7%Jun 1, 2026
RBC CapitalAnalyst unavailable$170$143.24 -28.0%May 14, 2026
DaiwaIllumina to Outperform$155$145 -34.3%May 14, 2026
Canaccord GenuityAnalyst unavailable$140$126.74 -40.7%May 1, 2026
BarclaysAnalyst unavailable$122$126.74 -48.3%May 1, 2026
Piper SandlerAnalyst unavailable$170$119.72 -28.0%Feb 9, 2026
Robert W. BairdCatherine Ramsey Schulte$137$120.22 -41.9%Feb 6, 2026
UBSAnalyst unavailable$135$121.26 -42.8%Feb 6, 2026
Evercore ISIAnalyst unavailable$150$121.13 -36.4%Feb 6, 2026
GuggenheimSubbu Nambi$170$150.38 -28.0%Jan 26, 2026
Canaccord GenuityAnalyst unavailable$150$150.28 -36.4%Jan 26, 2026
Stifel NicolausDaniel Arias$155$141.65 -34.3%Jan 20, 2026
Evercore ISIVijay Kumar$155$138.5 -34.3%Jan 5, 2026
GuggenheimAnalyst unavailable$144$138.11 -39.0%Jan 5, 2026
BarclaysAnalyst unavailable$110$134.85 -53.4%Dec 15, 2025
Evercore ISIVijay Kumar$142$121.59 -39.8%Oct 31, 2025
Robert W. BairdAnalyst unavailable$109$115.78 -53.8%Oct 31, 2025
UBSAnalyst unavailable$120$115.78 -49.2%Oct 31, 2025
Canaccord GenuityAnalyst unavailable$112$99.01 -52.5%Oct 31, 2025
BarclaysLuke Sergott$100$99.01 -57.6%Oct 31, 2025
Robert W. BairdAnalyst unavailable$105$99.97 -55.5%Oct 24, 2025
BarclaysAnalyst unavailable$95$102.26 -59.7%Oct 2, 2025
RBC CapitalAnalyst unavailable$124$97.82 -47.5%Sep 2, 2025
Morgan StanleyAnalyst unavailable$105$98.44 -55.5%Aug 4, 2025
StephensAnalyst unavailable$110$98.44 -53.4%Aug 4, 2025
BarclaysLuke Sergott$85$91.52 -64.0%Jun 24, 2025
Piper SandlerDavid Westenberg$185$80.9 -21.6%May 15, 2025
Canaccord GenuityAnalyst unavailable$115$84.52 -51.3%Mar 11, 2025
Robert W. BairdAnalyst unavailable$90$85.69 -61.9%Mar 5, 2025
National BankAnalyst unavailable$100$88.74 -57.6%Feb 28, 2025
HSBCAnalyst unavailable$100$88.74 -57.6%Feb 28, 2025
BarclaysLuke Sergott$130$131.1 -44.9%Feb 3, 2025
BernsteinEve Burstein$140$136.69 -40.7%Jan 10, 2025
Evercore ISIVijay Kumar$180$130.93 -23.7%Jan 2, 2025
Robert W. BairdCatherine Ramsey Schulte$139$156.21 -41.1%Nov 6, 2024
Canaccord GenuityKyle Mikson$145$156.21 -38.6%Nov 5, 2024
BarclaysLuke Sergott$145$156.21 -38.6%Nov 5, 2024
HSBCShubhangi Gupta$180$143.89 -23.7%Oct 17, 2024
Argus ResearchJasper Hellweg$150$131.46 -36.4%Aug 28, 2024
DaiwaNarumi Nakagiri$154$130.04 -34.7%Aug 16, 2024
ScotiabankSung Ji Nam$164$127.32 -30.5%Aug 15, 2024
BarclaysLuke Sergott$125$123.58 -47.0%Aug 14, 2024
Piper SandlerDavid Westenberg$195$124.54 -17.4%Aug 13, 2024
Robert W. BairdCatherine Ramsey Schulte$124$125.39 -47.5%Aug 7, 2024
Piper SandlerDave Westenberg$200$122.5 -15.3%Jul 30, 2024
Robert W. BairdCatherine Ramsey Schulte$119$110.24 -49.6%Jun 25, 2024
Evercore ISIVijay Kumar$175$110.96 -25.8%Jun 11, 2024
Wolfe ResearchDoug Schenkel$175$111.71 -25.8%Jun 6, 2024
Canaccord GenuityKyle Mikson$130$102.06 -44.9%Jun 4, 2024
JefferiesTycho Peterson$115$104.28 -51.3%Jun 3, 2024
Evercore ISIVijay Kumar$200$130.48 -15.3%Apr 12, 2024
Stifel NicolausDaniel Arias$225$185.2 -4.7%Aug 10, 2023
Leerink PartnersAnalyst unavailable$250$215.74 +5.9%Feb 8, 2023
CitigroupAnalyst unavailable$180$205.62 -23.7%Dec 12, 2022
RBC CapitalAnalyst unavailable$282$205.98 +19.5%Dec 7, 2022
Evercore ISIVijay Kumar$250$193.81 +5.9%Sep 29, 2022
Piper SandlerDavid Westenberg$320$196.07 +35.6%Sep 5, 2022
Piper SandlerDavid Westenberg$360$233.56 +52.5%May 15, 2022
Morgan StanleyTejas Savant$350$219.67 +48.3%May 10, 2022
Canaccord GenuityKyle Mikson$520$249.05 +120.3%May 8, 2022
Piper SandlerDavid Westenberg$460$311.97 +94.9%Feb 21, 2022
Cowen & Co.Dan Brennan$562$329.45 +138.1%Feb 14, 2022
Stifel NicolausDaniel Arias$480$365.94 +103.4%Jan 23, 2022
BarclaysLuke Sergott$400$423.8 +69.5%Jan 11, 2022
Morgan StanleyTejas Savant$425$378.93 +80.1%Jan 6, 2022
CitigroupPatrick B Donnelly$400$378.93 +69.5%Jan 6, 2022
Canaccord GenuityKyle Mikson CFA$555$457.16 +135.2%Aug 31, 2021
Evercore ISIVijay Kumar$400$407.45 +69.5%Jun 1, 2021
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Company context

Snapshot as of publication

Illumina, Inc. specializes in delivering advanced genetic and genomic analysis tools, primarily through sequencing and array technologies. The company's offerings empower clients across various sectors to integrate genomic insights into both research and clinical environments, with applications spanning critical fields like life sciences, cancer diagnostics, reproductive health, agriculture, and innovative new domains. Illumina's portfolio encompasses specialized instrumentation and necessary consumables for genetic analysis, alongside comprehensive genotyping and sequencing services.…

Historical context

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Sources

  1. Earnings call transcript and parsed analysis · 2026-07-31T01:05:52.285948+00:00
  2. FN2 earnings calendar · 2026-09-04T01:23:15.205020+00:00
  3. Polygon adjusted daily market bars · 2026-10-31T10:30:41.804459+00:00
  4. Financial Modeling Prep analyst price-target consensus and quote snapshot · 2026-10-31T10:30:41.801658+00:00

Methodology

Reported and consensus figures come from FN2's earnings event records. Market reaction and volume are calculated from daily adjusted bars around the event; abnormal move subtracts the SPY move over the same window.

Analyst target low, average, and high values are derived at request time from each named analyst's latest persisted FMP target. The current-price marker comes from FN2's persisted market snapshot. They are sell-side estimates, not an FN2 valuation or recommendation.

Transcript intelligence is a structured synthesis of the current and prior earnings-call analyses. Missing values stay missing and are never estimated.

By FN2 Research · Updated · As of 2026-10-31. For educational purposes only; not investment advice.