Glaukos Corporation · GKOS · FY2025 Q4 · Calendar Q1 2026

Glaukos grows Q4 sales as Epioxa launch and payer access move to the fore

Glaukos’s record sales and maintained FY2026 outlook support a growth case led by iDose TR and Epioxa, but sustained execution depends on adoption, payer coverage and managing launch-related costs. The quarter’s revenue beat alongside an EPS shortfall makes profitability and launch progress important evidence to monitor.

Reported After market closeNYSEHealthcare $14.07B market cap
100quality score

Earnings scorecard

Reported versus consensus
Reported EPS $-0.28 Consensus $-0.22
EPS surprise -27.3% Reported versus consensus
Reported revenue $143.1M Consensus $136.4M
Revenue surprise +4.9% Reported versus consensus

Market reaction

event-close to next-session close
Stock move +13.5% Event window
SPY move +0.5% Same window
Abnormal move +13.0% Stock minus SPY
Volume 2.2× Versus trailing sessions
Subsequent drift -14.7% Up to 20 sessions
GKOSSPY benchmark

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Transcript intelligence

What changed

Management reported record FY2025 fourth-quarter and full-year sales, reaffirmed FY2026 sales guidance, and highlighted iDose TR’s expanded re-administration label and Epioxa’s early site-of-care buildout. The reported quarter also exceeded the revenue estimate but fell short of the EPS estimate. Compared with the prior-quarter analysis, the focus has shifted from planned launches toward early commercialization, access and investment execution.

Guidance delta

Management maintained FY2026 net-sales guidance at $600 million to $620 million; no change was reported in the supplied analysis.

Key takeaways

  • Q4 net sales were $143.1 million versus a $136.4 million estimate, while EPS was -$0.28 versus a -$0.22 estimate.
  • Management reaffirmed FY2026 net-sales guidance of $600 million to $620 million, framing iDose TR and Epioxa as major growth drivers.
  • Management cited iDose TR adoption, its unlimited re-administration label and Epioxa’s developing U.S. site-of-care reach as commercial supports.
  • Operating expenses are expected to rise in the mid-teens percentage range as Glaukos invests in launches and targets cash-flow breakeven in 2026.

Management priorities

  • Scale iDose TR adoption and surgeon training; advance Phase III iDose TREX and Phase IIIb iDose TRIO trials.
  • Expand Epioxa’s site-of-care network, pursue payer coverage and move toward the permanent J-code described in the analysis.
  • Continue iStent infinite’s European commercialization and advance the iLink, ILution and retinal programs.

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Earnings History

Estimate Beat Miss Match
GKOS REVENUE earnings history estimate and actual scatter chart 10 reported fiscal quarters and 4 future estimate-only quarters. Q4 '23 estimate $78M Q4 '23 actual $82M, beat Q1 '24 estimate $80M Q1 '24 actual $86M, beat Q2 '24 estimate $89M Q2 '24 actual $96M, beat Q3 '24 estimate $101M Q3 '24 actual $97M, miss Q2 '25 estimate $122M Q2 '25 actual $124M, beat Q3 '25 estimate $129M Q3 '25 actual $134M, beat Q4 '25 estimate $136M Q4 '25 actual $143M, beat Q1 '26 estimate $137M Q1 '26 actual $151M, beat Q2 '26 estimate $151M Q2 '26 actual $186M, beat Q3 '26 estimate $168M Q3 '26 actual $211M, beat Q4 '26 estimate $227M Q1 '27 estimate $216M Q2 '27 estimate $244M Q3 '27 estimate $248M
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Analyst Consensus ?

ConsensusBuy25 ratings
Bullish1872.0%
Neutral624.0%
Bearish14.0%

Analyst 52W Price Targets

$237.6Previous close
$42Low
$177.38Average
$255High

Latest persisted target per named analyst; persisted previous close from FN2's market snapshot as of Nov 2, 2026. Not an FN2 forecast.

Firm-level rating actions

FMP grade actions identify the grading firm, not a named analyst.

FirmRatingPrior ratingActionDate
Wells Fargo Overweight OverweightMaintainOct 29, 2026
Truist Securities Buy BuyMaintainOct 29, 2026
Stifel Buy BuyMaintainOct 29, 2026
Piper Sandler Overweight OverweightMaintainOct 29, 2026
Needham Buy BuyMaintainOct 29, 2026
Show 20 more rating actions

Named analyst price targets

Upside is calculated against the persisted previous close $237.6. FMP does not supply a rating on these named-analyst rows.

FirmAnalyst52W targetPrice when postedUpsideDate
H.C. WainwrightYi Chen$248$237.73 +4.4%Oct 29, 2026
Stifel NicolausThomas Stephan$225$181.43 -5.3%Oct 29, 2026
Piper SandlerMatt O'Brien$240$181.43 +1.0%Oct 29, 2026
NeedhamDavid Saxon$251$181.43 +5.6%Oct 29, 2026
Mizuho SecuritiesAnthony Petrone$225$181.43 -5.3%Oct 29, 2026
See 61 more

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Company context

Snapshot as of publication

Glaukos Corporation operates as an ophthalmic medical technology and pharmaceutical enterprise, primarily focused on pioneering novel therapies for glaucoma, corneal disorders, and retinal diseases. The company offers a range of micro-bypass stents, including iStent, iStent inject, and iStent inject W. These devices are designed to enhance aqueous humor outflow, being inserted during cataract surgery to treat mild-to-moderate open-angle glaucoma. Its promising product pipeline features iStent Infinite, a three-stent system intended for standalone use in patients with refractory glaucoma, as well as iDose TR, a targeted injectable implant that utilizes Glaukos's micro-scale device platform to deliver therapeutic levels of medication. The company distributes its products through a direct sales organization and a network of distributors, serving markets across the United States and internationally. Glaukos Corporation, founded in 1998, is headquartered in San Clemente, California.

Historical context

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Sources

  1. Earnings call transcript and parsed analysis · 2026-05-11T10:29:34.698584+00:00
  2. FN2 earnings calendar · 2026-07-26T00:37:12.209961+00:00
  3. Polygon adjusted daily market bars · 2026-11-02T06:30:43.471891+00:00
  4. Financial Modeling Prep analyst price-target consensus and quote snapshot · 2026-11-02T06:30:43.469141+00:00

Methodology

Reported and consensus figures come from FN2's earnings event records. Market reaction and volume are calculated from daily adjusted bars around the event; abnormal move subtracts the SPY move over the same window.

Analyst target low, average, and high values are derived at request time from each named analyst's latest persisted FMP target. The current-price marker comes from FN2's persisted market snapshot. They are sell-side estimates, not an FN2 valuation or recommendation.

Transcript intelligence is a structured synthesis of the current and prior earnings-call analyses. Missing values stay missing and are never estimated.

By FN2 Research · Updated · As of 2026-11-02. For educational purposes only; not investment advice.