Guardant Health, Inc. · GH · FY2026 Q3 · Calendar Q4 2026

Guardant Health raises 2026 outlook as Shield growth accelerates

The supplied Q3 analysis supports a growth case built on expansion across oncology, screening and biopharma/data, with Shield growth and broader payer coverage as important contributors. The raised outlook and cost-reduction work are constructive, but the thesis depends on sustained demand, reimbursement progress and successful regulatory execution.

Why did GH fall 9.0% after beating EPS estimates in FY2026 Q3?

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Reported After market closeNASDAQHealthcare $20.59B market cap
100quality score

Earnings scorecard

Reported versus consensus
Reported EPS $-0.29 Consensus $-0.75
EPS surprise +61.3% Reported versus consensus
Reported revenue $361.0M Consensus $350.7M
Revenue surprise +2.9% Reported versus consensus

Market reaction

close-to-close (session unavailable)
Stock move -9.0% Event window
SPY move -4.4% Same window
Abnormal move -4.6% Stock minus SPY
Volume 2.3× Versus trailing sessions
Subsequent drift 0.0% Up to 20 sessions
GHSPY benchmark

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Transcript intelligence

What changed

Management raised its full-year 2026 revenue outlook to $1.36–$1.37 billion from the prior quarter's $1.34–$1.36 billion range. The supplied analysis also describes revenue growth as accelerating across segments and Shield revenue growth of 180%.

Guidance delta

Full-year 2026 revenue guidance increased to $1.36–$1.37 billion. The supplied analysis also cites a 65% non-GAAP gross-margin target; it does not provide a prior-quarter comparison for that target.

Key takeaways

  • The supplied Q3 analysis reports revenue up 36%, with growth across oncology, screening and biopharma/data.
  • Shield revenue grew 180%, and management described payer-coverage expansion adding about 30 million lives.
  • Management highlighted FDA approval for Guardant360 CDx for ESR1 mutations, Wave 4 Smart Apps and the Reveal Ultra launch.
  • The analysis cites a lower-cost Shield workflow that brought cost per test to $330, ahead of schedule.

Management priorities

  • Expand Shield commercial reach and coverage, including planned national direct-to-consumer campaigns in 2027.
  • Advance Guardant360 Tissue through PMA submission and pursue relevant regulatory and reimbursement milestones.
  • Continue Shield cost reduction, including commissioning a new automated Palo Alto lab and targeting $200 per test by end-2028.

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Earnings History

Estimate Beat Miss Match
GH EPS earnings history estimate and actual scatter chart 10 reported fiscal quarters and 2 future estimate-only quarters. Q2 '24 estimate $-0.57 Q2 '24 actual $-0.48, beat Q3 '24 estimate $-0.74 Q3 '24 actual $-0.45, beat Q2 '25 estimate $-0.52 Q2 '25 actual $-0.44, beat Q3 '25 estimate $-0.48 Q3 '25 actual $-0.39, beat Q4 '25 estimate $-0.77 Q4 '25 actual $-0.90, miss Q1 '26 estimate $-0.81 Q1 '26 actual $-0.85, miss Q2 '26 estimate $-0.76 Q2 '26 actual $-0.90, miss Q3 '26 estimate $-0.75 Q3 '26 actual $-0.29, beat Q4 '26 estimate $-0.63 Q1 '27 estimate $-0.58
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Analyst Consensus ?

ConsensusBuy31 ratings
Bullish3096.8%
Neutral00.0%
Bearish13.2%

Analyst 52W Price Targets

$148.96Current
$28Low
$154.85Average
$225High

Latest persisted target per named analyst; persisted current price from FN2's market snapshot as of Nov 6, 2026. Not an FN2 forecast.

Firm-level rating actions

FMP grade actions identify the grading firm, not a named analyst.

FirmRatingPrior ratingActionDate
BTIG Buy BuyMaintainOct 27, 2026
Morgan Stanley Overweight OverweightMaintainOct 13, 2026
Barclays Overweight OverweightMaintainOct 7, 2026
Guggenheim Buy BuyMaintainOct 1, 2026
UBS Buy BuyMaintainSep 9, 2026
Stephens & Co. Overweight OverweightMaintainAug 4, 2026
Piper Sandler Overweight OverweightMaintainAug 4, 2026
Stifel Buy BuyMaintainAug 3, 2026
TD Cowen Buy BuyMaintainJul 31, 2026
RBC Capital Outperform OutperformMaintainJul 31, 2026
Mizuho Outperform OutperformMaintainJul 31, 2026
JP Morgan Overweight OverweightMaintainJul 31, 2026
Canaccord Genuity Buy BuyMaintainJul 14, 2026
Citigroup Buy BuyMaintainJul 8, 2026
Evercore ISI Group Outperform OutperformMaintainJul 6, 2026
B of A Securities Buy BuyMaintainJul 6, 2026
Bernstein Outperform OutperformMaintainJul 2, 2026
Goldman Sachs Buy BuyMaintainJun 5, 2026
Wells Fargo Overweight OverweightMaintainFeb 20, 2026
Leerink Partners Outperform OutperformMaintainFeb 20, 2026
Wolfe Research Outperform Peer PerformUpgradeSep 25, 2025
Scotiabank Sector Outperform Sector OutperformMaintainJul 31, 2025
Raymond James Outperform OutperformMaintainJul 31, 2025
TD Securities Buy BuyMaintainMay 1, 2025
Craig-Hallum Buy BuyMaintainAug 8, 2024
Credit Suisse Outperform OutperformMaintainMay 10, 2023
OTR Global Negative MixedDowngradeMay 1, 2023
Cowen & Co. Outperform OutperformMaintainFeb 24, 2023
SVB Leerink Outperform OutperformMaintainFeb 24, 2022
Bank of America Buy NeutralUpgradeApr 10, 2019
William Blair Outperform OutperformMaintainOct 29, 2018
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Named analyst price targets

Upside is calculated against the persisted current price $148.96. FMP does not supply a rating on these named-analyst rows.

FirmAnalyst52W targetPrice when postedUpsideDate
BTIGMark Massaro$210$173.25 +41.0%Oct 27, 2026
Morgan StanleyKallum Titchmarsh$200$162.99 +34.3%Oct 12, 2026
BarclaysLuke Sergott$220$170.69 +47.7%Oct 7, 2026
GuggenheimAnalyst unavailable$200$177.24 +34.3%Oct 1, 2026
BernsteinEve Burstein$210$161.25 +41.0%Sep 10, 2026
UBSAnalyst unavailable$225$160.98 +51.0%Sep 9, 2026
Redburn PartnersAnalyst unavailable$203$161.41 +36.3%Sep 8, 2026
Morgan StanleyAnalyst unavailable$185$160.36 +24.2%Aug 4, 2026
StephensAnalyst unavailable$195$158.83 +30.9%Aug 4, 2026
Piper SandlerAnalyst unavailable$193$158.83 +29.6%Aug 4, 2026
RBC CapitalDan Leonard$200$161.87 +34.3%Jul 31, 2026
RBC CapitalAnalyst unavailable$210$161 +41.0%Jul 31, 2026
Stifel NicolausDaniel Arias$180$152.35 +20.8%Jul 31, 2026
Goldman SachsAnalyst unavailable$210$152.35 +41.0%Jul 31, 2026
Mizuho SecuritiesAnthony Petrone$200$152.35 +34.3%Jul 31, 2026
BTIGMark Massaro$195$152.35 +30.9%Jul 31, 2026
BarclaysAnalyst unavailable$200$152.35 +34.3%Jul 31, 2026
GuggenheimAnalyst unavailable$190$162.96 +27.6%Jul 16, 2026
Canaccord GenuityKyle Mikson$205$158.4 +37.6%Jul 14, 2026
Morgan StanleyAnalyst unavailable$175$156.17 +17.5%Jul 9, 2026
Evercore ISIVijay Kumar$200$169.45 +34.3%Jul 6, 2026
BernsteinEve Burstein$200$170.77 +34.3%Jul 2, 2026
BTIGAnalyst unavailable$190$170.19 +27.6%Jul 1, 2026
GuggenheimAnalyst unavailable$160$149.22 +7.4%Jun 29, 2026
UBSAnalyst unavailable$150$130.83 +0.7%Jun 24, 2026
RBC CapitalDan Leonard$185$130.9 +24.2%Jun 11, 2026
Mizuho SecuritiesAnalyst unavailable$175$125.61 +17.5%Jun 8, 2026
Goldman SachsEvie Koslosky$165$133.06 +10.8%Jun 5, 2026
Evercore ISIAnalyst unavailable$160$129.14 +7.4%Jun 2, 2026
BTIGAnalyst unavailable$160$127.41 +7.4%May 27, 2026
BTIGMark Massaro$155$118.95 +4.1%May 26, 2026
Piper SandlerAnalyst unavailable$127$119.32 -14.7%May 21, 2026
Piper SandlerDavid Westenberg$135$96.71 -9.4%May 12, 2026
BarclaysLuke Sergott$115$82.21 -22.8%Apr 14, 2026
Piper SandlerAnalyst unavailable$130$94.42 -12.7%Feb 24, 2026
Raymond JamesAnalyst unavailable$129$97.49 -13.4%Feb 23, 2026
Evercore ISIAnalyst unavailable$110$106.84 -26.2%Feb 20, 2026
BTIGAnalyst unavailable$145$106.38 -2.7%Feb 20, 2026
Stifel NicolausAnalyst unavailable$130$106.38 -12.7%Feb 20, 2026
Canaccord GenuityAnalyst unavailable$135$106.38 -9.4%Feb 20, 2026
BarclaysAnalyst unavailable$130$106.38 -12.7%Feb 20, 2026
Robert W. BairdCatherine Schulte$120$104.85 -19.4%Feb 17, 2026
UBSAnalyst unavailable$175$111 +17.5%Jan 30, 2026
GuggenheimAnalyst unavailable$135$115.69 -9.4%Jan 26, 2026
Stifel NicolausAnalyst unavailable$120$108.74 -19.4%Jan 9, 2026
Mizuho SecuritiesAnalyst unavailable$135$108.74 -9.4%Jan 9, 2026
GuggenheimSubbu Nambi$115$99 -22.8%Jan 5, 2026
Evercore ISIVijay Kumar$105$101.74 -29.5%Jan 5, 2026
Canaccord GenuityAnalyst unavailable$125$99.74 -16.1%Dec 22, 2025
Mizuho SecuritiesAnalyst unavailable$120$100 -19.4%Dec 17, 2025
Leerink PartnersAnalyst unavailable$155$104 +4.1%Dec 15, 2025
Wells FargoBrandon Couillard$120$102.04 -19.4%Dec 15, 2025
BarclaysAnalyst unavailable$120$102.04 -19.4%Dec 15, 2025
BTIGAnalyst unavailable$140$101.34 -6.0%Dec 12, 2025
Morgan StanleyTejas Savant$130$105.22 -12.7%Dec 1, 2025
UBSDan Leonard$110$95.29 -26.2%Oct 30, 2025
BTIGMark Massaro$100$95.55 -32.9%Oct 30, 2025
Mizuho SecuritiesBradley Bowers$100$72.27 -32.9%Oct 30, 2025
Canaccord GenuityKyle Mikson$100$72.27 -32.9%Oct 30, 2025
BarclaysAnalyst unavailable$85$72.27 -42.9%Oct 30, 2025
Piper SandlerAnalyst unavailable$90$67.51 -39.6%Oct 22, 2025
BarclaysAnalyst unavailable$70$62.65 -53.0%Oct 2, 2025
Canaccord GenuityKyle Mikson$75$60.18 -49.7%Sep 26, 2025
Stifel NicolausAnalyst unavailable$70$60.18 -53.0%Sep 25, 2025
BTIGMark Massaro$80$60.75 -46.3%Sep 25, 2025
Stifel NicolausDaniel Arias$73$62.64 -51.0%Sep 25, 2025
Wolfe ResearchDoug Schenkel$75$61.23 -49.7%Sep 25, 2025
China Renaissance Securities (US) Inc.Tempus AI$70$49.9 -53.0%Jun 25, 2025
Morgan StanleyAnalyst unavailable$52$42.66 -65.1%Mar 5, 2025
UBSDan Leonard$40$27.68 -73.1%Aug 21, 2024
Craig-HallumBill Bonello$37$31.36 -75.2%Aug 8, 2024
JefferiesTycho Peterson$40$33.96 -73.1%Aug 8, 2024
BTIGMark Massaro$50$35.28 -66.4%Jul 29, 2024
GuggenheimSubbu Nambi$36$28.88 -75.8%Jun 28, 2024
Canaccord GenuityKyle Mikson$38$27.41 -74.5%Jun 4, 2024
JefferiesTycho Peterson$32$27.1 -78.5%Jun 3, 2024
BTIGMark Massaro$45$22.51 -69.8%May 23, 2024
Canaccord GenuityKyle Mikson$30$23.01 -79.9%May 22, 2024
Craig-HallumChase Knickerbocker$28$17.94 -81.2%Apr 24, 2024
Piper SandlerDavid Westenberg$40$27.59 -73.1%Sep 27, 2023
Goldman SachsAnalyst unavailable$45$29.56 -69.8%Feb 6, 2023
Morgan StanleyTejas Savant$80$41.26 -46.3%Dec 16, 2022
Canaccord GenuityKyle Mikson$65$41.26 -56.4%Dec 16, 2022
StephensMason Carrico$99$59.78 -33.5%Oct 5, 2022
Goldman SachsAnalyst unavailable$80$54.25 -46.3%Aug 8, 2022
J.P. MorganJulia Qin$125$39.32 -16.1%May 9, 2022
Goldman SachsMatthew Sykes$160$117.9 +7.4%Jun 3, 2021
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Company context

Snapshot as of publication

Guardant Health, Inc., established in Redwood City, California, in 2011, is a precision oncology company that delivers a range of diagnostic blood tests, comprehensive data sets, and advanced analytical solutions both within the United States and internationally. For patients with advanced-stage cancer, the company's core offerings include several liquid biopsy-based tests such as Guardant360 (available in LDT and CDx versions) and GuardantOMNI. Complementing these diagnostic tools, Guardant Health also provides GuardantINFORM, an in-silico research platform leveraging an extensive clinical-genomic liquid biopsy dataset derived from advanced cancer patients. Innovation is a key focus, with the company currently developing the LUNAR-2 test, designed for the early detection of colorectal cancer in eligible asymptomatic individuals.…

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Sources

  1. Earnings call transcript and parsed analysis · 2026-11-06T06:16:34.553995+00:00
  2. FN2 earnings calendar · 2026-11-06T01:23:16.275024+00:00
  3. Polygon adjusted daily market bars · 2026-11-06T09:40:45.921941+00:00
  4. Financial Modeling Prep analyst price-target consensus and quote snapshot · 2026-11-06T09:40:45.919318+00:00

Methodology

Reported and consensus figures come from FN2's earnings event records. Market reaction and volume are calculated from daily adjusted bars around the event; abnormal move subtracts the SPY move over the same window.

Analyst target low, average, and high values are derived at request time from each named analyst's latest persisted FMP target. The current-price marker comes from FN2's persisted market snapshot. They are sell-side estimates, not an FN2 valuation or recommendation.

Transcript intelligence is a structured synthesis of the current and prior earnings-call analyses. Missing values stay missing and are never estimated.

By FN2 Research · Updated · As of 2026-11-06. For educational purposes only; not investment advice.