AstraZeneca PLC · AZN · FY2026 Q1 · Calendar Q2 2026

AstraZeneca Q1 2026: Oncology Strength Offsets CVRM Headwinds

The quarter's reported growth and maintained full-year outlook support a constructive operating picture, but the durability of growth depends on pipeline execution and managing CVRM, pricing, and competitive pressures.

Reported Before market openNYSEHealthcare $289.47B market cap
90quality score

Earnings scorecard

Reported versus consensus
Reported EPS $2.58 Consensus $2.57
EPS surprise +0.4% Reported versus consensus
Reported revenue $15.29B Consensus $14.93B
Revenue surprise +2.4% Reported versus consensus

Market reaction

prior-close to event-session close
Stock move -0.8% Event window
SPY move -0.0% Same window
Abnormal move -0.8% Stock minus SPY
Volume 2.3× Versus trailing sessions
Subsequent drift +0.1% Up to 20 sessions
AZNSPY benchmark

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Transcript intelligence

What changed

The supplied transcript analysis reports revenue growth of 8% year over year and operating-profit growth of 12%, with oncology and rare disease growth offsetting CVRM headwinds. The event scorecard shows EPS of 2.58 versus 2.57 estimated and revenue of 15.288 billion versus 14.93254 billion estimated. Full-year guidance was maintained.

Guidance delta

Maintained: the transcript analysis says management reaffirmed full-year revenue growth in the mid- to high-single digits and low-double-digit EPS growth.

Key takeaways

  • Oncology and rare disease were identified as growth drivers, while CVRM remained a headwind.
  • The event scorecard shows reported EPS and revenue modestly above estimates.
  • Management maintained the full-year outlook described in the transcript analysis.
  • Pipeline development and manufacturing capacity were emphasized as investment priorities.

Management priorities

  • Advance pipeline programs and prepare launches identified in the call, including baxdrostat, camizestrant, and tozorakimab.
  • Expand ADC manufacturing capacity in Singapore and Qingdao, and invest in pipeline development.
  • Pursue broader COPD indications and multiple Phase III programs, as described in the transcript analysis.

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Earnings History

Estimate Beat Miss Match
AZN EPS earnings history estimate and actual scatter chart 9 reported fiscal quarters and 4 future estimate-only quarters. Q1 '24 estimate $0.95 Q1 '24 actual $1.03, beat Q2 '24 estimate $0.96 Q2 '24 actual $0.99, beat Q2 '25 estimate $2.16 Q2 '25 actual $2.18, beat Q3 '25 estimate $2.29 Q3 '25 actual $2.38, beat Q4 '25 estimate $2.18 Q4 '25 actual $2.12, miss Q1 '26 estimate $2.57 Q1 '26 actual $2.58, match Q2 '26 estimate $2.50 Q2 '26 actual $2.63, beat Q3 '26 estimate $2.60 Q3 '26 actual $2.79, beat Q4 '26 estimate $2.41 Q1 '27 estimate $2.71 Q2 '27 estimate $2.67 Q3 '27 estimate $2.97
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Analyst Consensus ?

ConsensusHold40 ratings
Bullish1947.5%
Neutral1537.5%
Bearish615.0%

1 unmapped firm rating excluded from the percentages.

Analyst 52W Price Targets

$186.65Current
$156Low
$180Average
$216High

Latest persisted target per named analyst; persisted current price from FN2's market snapshot as of Nov 1, 2026. Not an FN2 forecast.

Firm-level rating actions

FMP grade actions identify the grading firm, not a named analyst.

FirmRatingPrior ratingActionDate
UBS Buy NeutralUpgradeFeb 13, 2025
Erste Group Buy HoldUpgradeSep 11, 2024
TD Cowen Buy BuyMaintainAug 12, 2024
Argus Research Buy BuyMaintainMay 30, 2024
BMO Capital Outperform OutperformMaintainApr 26, 2024
Deutsche Bank Hold SellUpgradeApr 16, 2024
Jefferies Hold BuyDowngradeJan 3, 2024
SVB Leerink Outperform OutperformMaintainNov 14, 2022
DZ Bank Hold SellUpgradeFeb 11, 2022
Morgan Stanley Overweight Equal WeightUpgradeDec 7, 2020
Cowen & Co. Outperform OutperformMaintainDec 2, 2019
Investec Hold BuyDowngradeNov 19, 2018
Argus Buy HoldUpgradeMay 5, 2018
Leerink Swann Market Perform Market PerformMaintainFeb 6, 2018
JP Morgan Overweight NeutralUpgradeDec 29, 2017
Bernstein Outperform Market PerformUpgradeSep 22, 2017
Liberum Hold BuyDowngradeSep 14, 2017
Credit Suisse Neutral UnderperformUpgradeMay 15, 2017
Exane BNP Paribas Neutral OutperformDowngradeSep 14, 2016
Goldman Sachs Sell NeutralDowngradeApr 11, 2016
HBSC Hold BuyDowngradeFeb 8, 2016
Oddo Securities Top Pick NeutralUpgradeJan 26, 2016
Barclays Equal Weight UnderweightUpgradeJan 19, 2016
HSBC Buy HoldUpgradeSep 2, 2015
Berenberg Buy HoldUpgradeJul 2, 2015
LBBW Research Hold SellUpgradeMay 19, 2015
SEB Enskilda Buy HoldUpgradeFeb 3, 2015
Danske Bank Sell BuyDowngradeMay 5, 2014
Panmure Gordon Buy HoldUpgradeApr 29, 2014
Panmure Buy HoldUpgradeApr 29, 2014
Societe Generale Hold SellUpgradeApr 28, 2014
Kepler Cheuvreux Hold ReduceUpgradeApr 28, 2014
Citigroup Buy NeutralUpgradeApr 22, 2014
Bank of America Underperform NeutralDowngradeMar 3, 2014
B of A Securities Underperform NeutralDowngradeMar 3, 2014
Bryan Garnier Neutral BuyDowngradeDec 20, 2013
Nordea Equity Buy SellUpgradeSep 16, 2013
Nordea Buy SellUpgradeSep 16, 2013
Swedbank Reduce SellMaintainAug 2, 2013
Natixis Neutral ReduceUpgradeMar 22, 2013
Pareto Securities Sell HoldDowngradeOct 26, 2012
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Named analyst price targets

Upside is calculated against the persisted current price $186.65. FMP does not supply a rating on these named-analyst rows.

FirmAnalyst52W targetPrice when postedUpsideDate
HSBCAnalyst unavailable$216$179.64 +15.7%Dec 10, 2025
Morgan StanleyAnalyst unavailable$206$180.34 +10.4%Dec 3, 2025
Berenberg BankLuisa Hector$194$141.64 +3.9%Jul 9, 2025
BMO CapitalEtzer Darout$176$162.38 -5.7%Nov 13, 2024
BMO CapitalEtzer Darout$178$159.88 -4.6%Sep 11, 2024
Argus ResearchJohn Eade$170$153.68 -8.9%May 30, 2024
BMO CapitalEtzer Darout$164$153.48 -12.1%May 28, 2024
Leerink PartnersAndrew Berens$158$129.72 -15.3%Jul 12, 2023
BMO CapitalAnalyst unavailable$164$139 -12.1%Jan 5, 2023
Leerink PartnersAnalyst unavailable$156$130.18 -16.4%Nov 11, 2022
Leerink PartnersAnalyst unavailable$150$134.34 -19.6%May 4, 2022
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Company context

Snapshot as of publication

AstraZeneca PLC operates as a global biopharmaceutical leader, dedicated to the entire process of bringing prescription medicines to market, from their initial discovery and development through manufacturing and commercialization. The company's extensive portfolio of treatments, including prominent examples like Tagrisso, Farxiga, and Symbicort, addresses critical areas such as cardiovascular, renal, metabolic, and oncological conditions. Furthermore, it provides essential solutions for COVID-19 and various rare diseases, with products like Vaxzevria and Soliris.…

Historical context

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Sources

  1. Earnings call transcript and parsed analysis · 2026-05-11T10:29:34.698584+00:00
  2. FN2 earnings calendar · 2026-07-26T00:37:12.209961+00:00
  3. Polygon adjusted daily market bars · 2026-11-01T20:20:51.240119+00:00
  4. Financial Modeling Prep analyst price-target consensus and quote snapshot · 2026-11-01T20:20:51.237442+00:00

Methodology

Reported and consensus figures come from FN2's earnings event records. Market reaction and volume are calculated from daily adjusted bars around the event; abnormal move subtracts the SPY move over the same window.

Analyst target low, average, and high values are derived at request time from each named analyst's latest persisted FMP target. The current-price marker comes from FN2's persisted market snapshot. They are sell-side estimates, not an FN2 valuation or recommendation.

Transcript intelligence is a structured synthesis of the current and prior earnings-call analyses. Missing values stay missing and are never estimated.

By FN2 Research · Updated · As of 2026-11-01. For educational purposes only; not investment advice.