Axsome Therapeutics, Inc. · AXSM · FY2024 Q3 · Calendar Q4 2024
Axsome’s Q3 momentum meets a pipeline still dependent on trial results
The supplied analysis supports a constructive but conditional view: commercial momentum and market-access expansion are encouraging, while the next phase of value creation depends on clinical, regulatory, payer, and execution milestones.
Earnings scorecard
Reported versus consensusMarket reaction
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Transcript intelligence
What changed
Relative to the prior-quarter analysis, the focus shifted from NDA preparation and coverage expansion toward a broader set of late-stage readouts, planned launches, and sales-force scaling. The commercial trajectory remained strong, but dependence on pipeline execution stayed central.
Guidance delta
Maintained; the supplied analysis indicates no change to guidance sentiment.
Key takeaways
- Management highlighted record Q3 product revenue and double-digit growth from Auvelity and Sunosi.
- The next leg of the story depends on late-stage readouts, regulatory progress, and additional CNS indications.
- Commercial expansion and broader market access remain key execution levers.
Management priorities
- Expand the Auvelity sales force and deepen primary-care penetration.
- Advance AXS-07, AXS-05, AXS-12, and solriamfetol through planned regulatory and clinical milestones.
- Continue market-access initiatives and prepare for additional CNS launches.
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Analyst 52W Price Targets
Latest persisted target per named analyst; persisted current price from FN2's market snapshot as of Oct 25, 2026. Not an FN2 forecast.
Firm-level rating actions
FMP grade actions identify the grading firm, not a named analyst.
| Firm | Rating | Prior rating | Action | Date |
|---|---|---|---|---|
| RBC Capital | Outperform | Outperform | Maintain | Oct 8, 2026 |
| Deutsche Bank | Buy | Buy | Maintain | Sep 29, 2026 |
| Morgan Stanley | Equal Weight | Equal Weight | Maintain | Sep 25, 2026 |
| Truist Securities | Buy | Buy | Maintain | Sep 23, 2026 |
| Piper Sandler | Overweight | Overweight | Maintain | Sep 18, 2026 |
| HC Wainwright & Co. | Buy | Buy | Maintain | Aug 31, 2026 |
| Mizuho | Outperform | Outperform | Maintain | Aug 12, 2026 |
| Wells Fargo | Overweight | Overweight | Maintain | Aug 11, 2026 |
| Needham | Buy | Buy | Maintain | Aug 11, 2026 |
| Guggenheim | Buy | Buy | Maintain | Aug 11, 2026 |
| TD Cowen | Buy | Buy | Maintain | Jun 17, 2026 |
| Baird | Outperform | Outperform | Maintain | May 5, 2026 |
| Jefferies | Buy | Buy | Maintain | May 4, 2026 |
| UBS | Buy | Buy | Maintain | Apr 10, 2026 |
| Leerink Partners | Outperform | Outperform | Maintain | Jan 28, 2026 |
| B of A Securities | Buy | Buy | Maintain | Aug 5, 2025 |
| Cantor Fitzgerald | Overweight | Overweight | Maintain | Feb 19, 2025 |
| Citigroup | Buy | Buy | Maintain | May 7, 2024 |
| BTIG | Buy | Buy | Maintain | Dec 23, 2022 |
| SVB Leerink | Outperform | Outperform | Maintain | Nov 29, 2022 |
| Loop Capital | Buy | Buy | Maintain | Nov 1, 2022 |
| Cowen & Co. | Outperform | Outperform | Maintain | Jun 29, 2022 |
| Berenberg | Buy | Buy | Maintain | Jun 10, 2021 |
| H.C. Wainwright | Buy | Buy | Maintain | Dec 30, 2019 |
| William Blair | Outperform | Outperform | Maintain | Sep 18, 2019 |
| BTIG Research | Buy | Buy | Maintain | May 19, 2017 |
| Brean Capital | Buy | Buy | Maintain | Dec 17, 2015 |
Named analyst price targets
Upside is calculated against the persisted current price $145.04. FMP does not supply a rating on these named-analyst rows.
| Firm | Analyst | 52W target | Price when posted | Upside | Date |
|---|---|---|---|---|---|
| RBC Capital | Analyst unavailable | $295 | $168.6 | +103.4% | Oct 8, 2026 |
| Deutsche Bank | Analyst unavailable | $267 | $188.66 | +84.1% | Sep 29, 2026 |
| Morgan Stanley | Analyst unavailable | $247 | $198.57 | +70.3% | Sep 25, 2026 |
| Truist Financial | Srikripa Devarakonda | $285 | $203.1 | +96.5% | Sep 23, 2026 |
| Mizuho Securities | Graig Suvannavejh | $316 | $215.77 | +117.9% | Aug 12, 2026 |
| RBC Capital | Leonid Timashev | $297 | $219 | +104.8% | Aug 11, 2026 |
| Morgan Stanley | Analyst unavailable | $251 | $221.21 | +73.1% | Aug 11, 2026 |
| Needham | Ami Fadia | $268 | $220.89 | +84.8% | Aug 11, 2026 |
| Guggenheim | Analyst unavailable | $275 | $220.89 | +89.6% | Aug 11, 2026 |
| Wells Fargo | Analyst unavailable | $256 | $220.89 | +76.5% | Aug 11, 2026 |
| BMO Capital | Malcolm Hoffman | $310 | $221.64 | +113.7% | Jul 20, 2026 |
| RBC Capital | Leonid Timashev | $304 | $242.6 | +109.6% | Jul 7, 2026 |
| Jefferies | Andrew Tsai | $380 | $246.34 | +162.0% | Jun 11, 2026 |
| Deutsche Bank | David Hoang | $280 | $230.1 | +93.1% | May 5, 2026 |
| Morgan Stanley | Analyst unavailable | $242 | $230.11 | +66.9% | May 5, 2026 |
| Needham | Analyst unavailable | $267 | $230.63 | +84.1% | May 5, 2026 |
| RBC Capital | Leonid Timashev | $302 | $231 | +108.2% | May 5, 2026 |
| Robert W. Baird | Brian Skorney | $246 | $223.7 | +69.6% | May 5, 2026 |
| H.C. Wainwright | Analyst unavailable | $290 | $223.7 | +99.9% | May 5, 2026 |
| Oppenheimer | Analyst unavailable | $280 | $223.34 | +93.1% | May 4, 2026 |
| Guggenheim | Yatin Suneja | $260 | $227.31 | +79.3% | May 4, 2026 |
| Piper Sandler | Analyst unavailable | $258 | $227.26 | +77.9% | May 4, 2026 |
| Cantor Fitzgerald | Analyst unavailable | $272 | $227.39 | +87.5% | May 4, 2026 |
| Jefferies | Andrew Tsai | $275 | $227.92 | +89.6% | May 4, 2026 |
| Deutsche Bank | David Hoang | $281 | $227.35 | +93.7% | May 4, 2026 |
| H.C. Wainwright | Raghuram Selvaraju | $270 | $206.53 | +86.2% | May 4, 2026 |
| Oppenheimer | Analyst unavailable | $250 | $201.03 | +72.4% | May 1, 2026 |
| Morgan Stanley | Analyst unavailable | $217 | $207.75 | +49.6% | Apr 30, 2026 |
| UBS | Analyst unavailable | $259 | $179.26 | +78.6% | Apr 10, 2026 |
| RBC Capital | Analyst unavailable | $222 | $168.35 | +53.1% | Feb 24, 2026 |
| UBS | Analyst unavailable | $251 | $170.81 | +73.1% | Feb 24, 2026 |
| Morgan Stanley | Analyst unavailable | $207 | $174.76 | +42.7% | Feb 24, 2026 |
| Guggenheim | Analyst unavailable | $220 | $174.76 | +51.7% | Feb 24, 2026 |
| Wells Fargo | Analyst unavailable | $202 | $174.76 | +39.3% | Feb 24, 2026 |
| Wolfe Research | Rudy Li | $230 | $174.76 | +58.6% | Feb 23, 2026 |
| Truist Financial | Joon Lee | $200 | $173.55 | +37.9% | Feb 23, 2026 |
| Jefferies | Analyst unavailable | $215 | $173.9 | +48.2% | Feb 23, 2026 |
| Mizuho Securities | Analyst unavailable | $230 | $184.74 | +58.6% | Feb 19, 2026 |
| RBC Capital | Leonid Timashev | $219 | $184.5 | +51.0% | Jan 21, 2026 |
| H.C. Wainwright | Analyst unavailable | $260 | $177.27 | +79.3% | Jan 20, 2026 |
| Piper Sandler | Analyst unavailable | $223 | $174.14 | +53.8% | Jan 16, 2026 |
| Robert W. Baird | Analyst unavailable | $209 | $175.98 | +44.1% | Jan 13, 2026 |
| Wells Fargo | Analyst unavailable | $193 | $176.82 | +33.1% | Jan 13, 2026 |
| Morgan Stanley | Analyst unavailable | $204 | $170.69 | +40.7% | Jan 8, 2026 |
| UBS | Analyst unavailable | $248 | $175.14 | +71.0% | Jan 6, 2026 |
| Needham | Ami Fadia | $225 | $178.69 | +55.1% | Jan 5, 2026 |
| H.C. Wainwright | Raghuram Selvaraju | $200 | $178.69 | +37.9% | Jan 5, 2026 |
| Guggenheim | Yatin Suneja | $205 | $179.14 | +41.3% | Jan 2, 2026 |
| Mizuho Securities | Graig Suvannavejh | $217 | $182.86 | +49.6% | Dec 31, 2025 |
| Oppenheimer | Jay Olson | $220 | $182.64 | +51.7% | Dec 31, 2025 |
| H.C. Wainwright | Analyst unavailable | $185 | $134.11 | +27.6% | Nov 4, 2025 |
| RBC Capital | Analyst unavailable | $198 | $133.5 | +36.5% | Nov 4, 2025 |
| Morgan Stanley | Analyst unavailable | $196 | $133.81 | +35.1% | Nov 4, 2025 |
| Wells Fargo | Analyst unavailable | $157 | $135.75 | +8.2% | Nov 4, 2025 |
| Morgan Stanley | Sean Laaman | $194 | $127.94 | +33.8% | Oct 20, 2025 |
| Wells Fargo | Analyst unavailable | $163 | $123.47 | +12.4% | Sep 2, 2025 |
| Robert W. Baird | Joel Beatty | $162 | $112.16 | +11.7% | May 6, 2025 |
| Mizuho Securities | Graig Suvannavejh | $216 | $121.77 | +48.9% | Mar 27, 2025 |
| Robert W. Baird | Analyst unavailable | $160 | $127.15 | +10.3% | Mar 3, 2025 |
| Mizuho Securities | Graig Suvannavejh | $137 | $107.43 | -5.5% | Feb 3, 2025 |
| Truist Financial | Joon Lee | $190 | $107.43 | +31.0% | Feb 3, 2025 |
| Robert W. Baird | Joel Beatty | $132 | $107.43 | -9.0% | Feb 3, 2025 |
| Guggenheim | Yatin Suneja | $135 | $99.49 | -6.9% | Nov 12, 2024 |
| Mizuho Securities | Graig Suvannavejh | $106 | $90.58 | -26.9% | Sep 11, 2024 |
| Wells Fargo | Cerena Chen | $140 | $88.86 | -3.5% | Sep 3, 2024 |
| H.C. Wainwright | Raghuram Selvaraju | $180 | $83.21 | +24.1% | Aug 6, 2024 |
| Bank of America Securities | Jason Gerberry | $106 | $83.93 | -26.9% | Aug 6, 2024 |
| RBC Capital | Leonid Timashev | $131 | $84.85 | -9.7% | Jul 22, 2024 |
| RBC Capital | Leonid Timashev | $130 | $72.24 | -10.4% | Jun 5, 2024 |
| Piper Sandler | David Amsellem | $115 | $75.19 | -20.7% | May 28, 2024 |
| Morgan Stanley | Vikram Purohit | $115 | $74.14 | -20.7% | Apr 29, 2024 |
| Mizuho Securities | Graig Suvannavejh | $109 | $79.17 | -24.8% | Mar 28, 2024 |
| Robert W. Baird | Joel Beatty | $108 | $72.54 | -25.5% | Mar 18, 2024 |
| Piper Sandler | Analyst unavailable | $75 | $73.34 | -48.3% | Jan 5, 2023 |
| BTIG | Robert Hazlett | $98 | $75.13 | -32.4% | Dec 23, 2022 |
| Morgan Stanley | Analyst unavailable | $86 | $74.95 | -40.7% | Nov 29, 2022 |
| Leerink Partners | Analyst unavailable | $85 | $74.74 | -41.4% | Nov 29, 2022 |
| Guggenheim | Analyst unavailable | $80 | $55.48 | -44.8% | Nov 11, 2022 |
| Truist Financial | Joon Lee | $150 | $59.03 | +3.4% | Aug 19, 2022 |
| Mizuho Securities | Analyst unavailable | $49 | $34.04 | -66.2% | May 3, 2022 |
| Morgan Stanley | Analyst unavailable | $27 | $30.59 | -81.4% | Apr 27, 2022 |
| Truist Financial | Joon Lee | $90 | $30.98 | -37.9% | Mar 1, 2022 |
| Bank of America Securities | Ashwani Verma | $25 | $23.78 | -82.8% | Aug 10, 2021 |
Track every rating change on AXSM the moment it posts. Free to start.
Start freeCompany context
Snapshot as of publicationAxsome Therapeutics, Inc. is a biopharmaceutical company dedicated to discovering and advancing innovative treatments for a range of central nervous system (CNS) disorders within the United States. Its robust product pipeline features several promising candidates, including: AXS-05, an investigational therapy currently being developed for major depressive disorder and treatment-resistant depression. This compound is also in Phase III clinical evaluation for Alzheimer's disease agitation and has successfully finished Phase II trials investigating its use for smoking cessation.…
Historical context
All AXSM earningsHealthcare peers this season
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| ARGX argenx SE | FY2026 Q3 · Calendar Q4 2026 | — | -1.6% | argenx: VYVGART momentum and a broader late-stage pipeline |
| MEDP Medpace Holdings, Inc. | FY2026 Q3 · Calendar Q4 2026 | +9.0% | -1.3% | Medpace: Record awards lift backlog as 2026 outlook improves |
| MOH Molina Healthcare, Inc. | FY2026 Q3 · Calendar Q4 2026 | +12.7% | +0.8% | Molina reaffirms 2026 outlook as Florida contract scales |
Latest beats and misses
Who reports nextBeat on EPS
- FCNCAFY2026 Q3 · October 23, 2026+19.9% EPS+8.2% move
- FCNCNFY2026 Q3 · October 23, 2026+19.9% EPS+0.2% move
- FCNCOFY2026 Q3 · October 23, 2026+19.9% EPS+1.0% move
- FCNCPFY2026 Q3 · October 23, 2026+19.9% EPS+1.0% move
- RDYFY2027 Q2 · October 23, 2026+24.0% EPS-0.2% move
- SLBFY2026 Q3 · October 23, 2026+3.7% EPS+7.1% move
Missed on EPS
- INFYFY2027 Q2 · October 23, 2026-4.8% EPS-6.6% move
- BBDFY2026 Q3 · October 22, 2026-7.7% EPS+3.0% move
- SNAFY2026 Q3 · October 22, 2026-5.9% EPS-3.4% move
- SPOTFY2026 Q3 · October 22, 2026-11.6% EPS+11.1% move
- VRSNFY2026 Q3 · October 22, 2026-2.0% EPS-0.9% move
- HBANMFY2026 Q3 · October 22, 2026-5.3% EPS+0.5% move
Get the AXSM recap when the next report posts
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Sources
- Earnings call transcript and parsed analysis · 2026-05-11T10:29:34.698584+00:00
- FN2 earnings calendar · 2024-11-10T18:39:04.055137+00:00
- Polygon adjusted daily market bars · 2026-10-25T16:50:41.737514+00:00
- Financial Modeling Prep analyst price-target consensus and quote snapshot · 2026-10-25T16:50:41.733751+00:00
Methodology
Reported and consensus figures come from FN2's earnings event records. Market reaction and volume are calculated from daily adjusted bars around the event; abnormal move subtracts the SPY move over the same window.
Analyst target low, average, and high values are derived at request time from each named analyst's latest persisted FMP target. The current-price marker comes from FN2's persisted market snapshot. They are sell-side estimates, not an FN2 valuation or recommendation.
Transcript intelligence is a structured synthesis of the current and prior earnings-call analyses. Missing values stay missing and are never estimated.
By FN2 Research · Updated · As of 2026-10-25. For educational purposes only; not investment advice.