Axsome Therapeutics, Inc. · AXSM · FY2024 Q3 · Calendar Q4 2024

Axsome’s Q3 momentum meets a pipeline still dependent on trial results

The supplied analysis supports a constructive but conditional view: commercial momentum and market-access expansion are encouraging, while the next phase of value creation depends on clinical, regulatory, payer, and execution milestones.

Reported Before market openNASDAQHealthcare $7.60B market cap
80quality score

Earnings scorecard

Reported versus consensus
Reported EPS — Consensus $-1.41
EPS surprise — Reported versus consensus
Reported revenue — Consensus $98.1M
Revenue surprise — Reported versus consensus

Market reaction

prior-close to event-session close
Stock move +9.4% Event window
SPY move -0.3% Same window
Abnormal move +9.7% Stock minus SPY
Volume 4.0× Versus trailing sessions
Subsequent drift -1.8% Up to 20 sessions
AXSMSPY benchmark

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Transcript intelligence

What changed

Relative to the prior-quarter analysis, the focus shifted from NDA preparation and coverage expansion toward a broader set of late-stage readouts, planned launches, and sales-force scaling. The commercial trajectory remained strong, but dependence on pipeline execution stayed central.

Guidance delta

Maintained; the supplied analysis indicates no change to guidance sentiment.

Key takeaways

  • Management highlighted record Q3 product revenue and double-digit growth from Auvelity and Sunosi.
  • The next leg of the story depends on late-stage readouts, regulatory progress, and additional CNS indications.
  • Commercial expansion and broader market access remain key execution levers.

Management priorities

  • Expand the Auvelity sales force and deepen primary-care penetration.
  • Advance AXS-07, AXS-05, AXS-12, and solriamfetol through planned regulatory and clinical milestones.
  • Continue market-access initiatives and prepare for additional CNS launches.

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Earnings History

Estimate Beat Miss Match
AXSM EPS earnings history estimate and actual scatter chart 8 reported fiscal quarters and 4 future estimate-only quarters. Q4 '23 estimate $-1.21 Q4 '23 actual $-0.73, beat Q1 '24 estimate $-1.20 Q1 '24 actual $-1.09, beat Q2 '24 estimate $-1.30 Q2 '24 actual $-1.24, beat Q2 '25 estimate $-1.00 Q2 '25 actual $-0.92, beat Q3 '25 estimate $-0.82 Q3 '25 actual $-0.94, miss Q4 '25 estimate $-0.70 Q4 '25 actual $-0.71, match Q1 '26 estimate $-0.85 Q1 '26 actual $-1.26, miss Q2 '26 estimate $-0.89 Q2 '26 actual $-0.99, miss Q3 '26 estimate $-0.62 Q4 '26 estimate $-0.04 Q1 '27 estimate $-0.10 Q2 '27 estimate $0.49

Analyst Consensus ?

ConsensusBuy27 ratings
Bullish2696.3%
Neutral13.7%
Bearish00.0%

Analyst 52W Price Targets

$145.04Current
$25Low
$228.39Average
$380High

Latest persisted target per named analyst; persisted current price from FN2's market snapshot as of Oct 25, 2026. Not an FN2 forecast.

Firm-level rating actions

FMP grade actions identify the grading firm, not a named analyst.

FirmRatingPrior ratingActionDate
RBC Capital Outperform OutperformMaintainOct 8, 2026
Deutsche Bank Buy BuyMaintainSep 29, 2026
Morgan Stanley Equal Weight Equal WeightMaintainSep 25, 2026
Truist Securities Buy BuyMaintainSep 23, 2026
Piper Sandler Overweight OverweightMaintainSep 18, 2026
Show 22 more rating actions

Named analyst price targets

Upside is calculated against the persisted current price $145.04. FMP does not supply a rating on these named-analyst rows.

FirmAnalyst52W targetPrice when postedUpsideDate
RBC CapitalAnalyst unavailable$295$168.6 +103.4%Oct 8, 2026
Deutsche BankAnalyst unavailable$267$188.66 +84.1%Sep 29, 2026
Morgan StanleyAnalyst unavailable$247$198.57 +70.3%Sep 25, 2026
Truist FinancialSrikripa Devarakonda$285$203.1 +96.5%Sep 23, 2026
Mizuho SecuritiesGraig Suvannavejh$316$215.77 +117.9%Aug 12, 2026
See 78 more

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Company context

Snapshot as of publication

Axsome Therapeutics, Inc. is a biopharmaceutical company dedicated to discovering and advancing innovative treatments for a range of central nervous system (CNS) disorders within the United States. Its robust product pipeline features several promising candidates, including: AXS-05, an investigational therapy currently being developed for major depressive disorder and treatment-resistant depression. This compound is also in Phase III clinical evaluation for Alzheimer's disease agitation and has successfully finished Phase II trials investigating its use for smoking cessation.…

Historical context

All AXSM earnings

Healthcare peers this season

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Latest beats and misses

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Sources

  1. Earnings call transcript and parsed analysis · 2026-05-11T10:29:34.698584+00:00
  2. FN2 earnings calendar · 2024-11-10T18:39:04.055137+00:00
  3. Polygon adjusted daily market bars · 2026-10-25T16:50:41.737514+00:00
  4. Financial Modeling Prep analyst price-target consensus and quote snapshot · 2026-10-25T16:50:41.733751+00:00

Methodology

Reported and consensus figures come from FN2's earnings event records. Market reaction and volume are calculated from daily adjusted bars around the event; abnormal move subtracts the SPY move over the same window.

Analyst target low, average, and high values are derived at request time from each named analyst's latest persisted FMP target. The current-price marker comes from FN2's persisted market snapshot. They are sell-side estimates, not an FN2 valuation or recommendation.

Transcript intelligence is a structured synthesis of the current and prior earnings-call analyses. Missing values stay missing and are never estimated.

By FN2 Research · Updated · As of 2026-10-25. For educational purposes only; not investment advice.