argenx SE · ARGX · FY2024 Q4 · Calendar Q1 2025

argenx Q4: VYVGART momentum and pipeline expansion remain central

The supplied analysis supports a constructive but conditional view: VYVGART’s reported commercial momentum, broader delivery options, geographic expansion, and pipeline activity provide growth support, while pricing, regulatory, competitive, and clinical execution risks remain material.

Reported Before market openNASDAQHealthcare $65.12B market cap
80quality score

Earnings scorecard

Reported versus consensus
Reported EPS — Consensus $0.98
EPS surprise — Reported versus consensus
Reported revenue — Consensus $682.1M
Revenue surprise — Reported versus consensus

Market reaction

prior-close to event-session close
Stock move +0.3% Event window
SPY move -1.6% Same window
Abnormal move +1.9% Stock minus SPY
Volume 1.3× Versus trailing sessions
Subsequent drift -5.0% Up to 20 sessions
ARGXSPY benchmark

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Transcript intelligence

What changed

Relative to the prior-quarter analysis, the supplied Q4 analysis shows product revenues summarized at $2.2 billion with 98% year-over-year growth, adds emphasis on self-administration and global expansion, and highlights new pipeline candidates and a broader late-stage development effort.

Guidance delta

Management outlook was described as maintained, including expectations for profitability in 2025 while continuing R&D and commercial investment.

Key takeaways

  • Product revenue momentum was driven by VYVGART in myasthenia gravis and CIDP, with product revenues summarized at $2.2 billion and 98% year-over-year growth.
  • Management emphasized self-administration options, geographic expansion, and broader use in earlier lines of therapy.
  • The pipeline includes multiple Phase III and proof-of-concept programs, alongside newer candidates such as ARGX-213 and an anti-IL-6 antibody.

Management priorities

  • Expand VYVGART adoption across myasthenia gravis and CIDP.
  • Advance the prefilled syringe, future auto-injector, and global regulatory and reimbursement efforts.
  • Progress late-stage and proof-of-concept programs across autoimmune indications.

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Earnings History

Estimate Beat Miss Match
ARGX EPS earnings history estimate and actual scatter chart 7 reported fiscal quarters and 1 future estimate-only quarters. Q4 '23 estimate $-1.23 Q4 '23 actual $-1.68, miss Q1 '24 estimate $-0.71 Q1 '24 actual $-1.04, miss Q2 '24 estimate $-0.89 Q2 '24 actual $0.45, beat Q3 '24 estimate $0.10 Q3 '24 actual $1.39, beat Q2 '25 estimate $4.37 Q2 '25 actual $5.18, beat Q4 '25 estimate $6.27 Q4 '25 actual $5.90, miss Q2 '26 estimate $6.27 Q2 '26 actual $7.32, beat Q4 '26 estimate $7.51

Analyst Consensus ?

ConsensusBuy36 ratings
Bullish3288.9%
Neutral411.1%
Bearish00.0%

Analyst 52W Price Targets

$874.1Current
$326.27Low
$890.81Average
$1,400High

Latest persisted target per named analyst; persisted current price from FN2's market snapshot as of Oct 26, 2026. Not an FN2 forecast.

Firm-level rating actions

FMP grade actions identify the grading firm, not a named analyst.

FirmRatingPrior ratingActionDate
Wells Fargo Overweight OverweightMaintainOct 23, 2026
Morgan Stanley Overweight OverweightMaintainOct 23, 2026
Guggenheim Buy BuyMaintainOct 23, 2026
Evercore ISI Group Outperform OutperformMaintainOct 23, 2026
Baird Neutral NeutralMaintainOct 23, 2026
Show 31 more rating actions

Named analyst price targets

Upside is calculated against the persisted current price $874.1. FMP does not supply a rating on these named-analyst rows.

FirmAnalyst52W targetPrice when postedUpsideDate
Morgan StanleySean Laaman$1,190$875.76 +36.1%Oct 23, 2026
GuggenheimAnalyst unavailable$1,120$875.76 +28.1%Oct 23, 2026
Robert W. BairdCollen Kusy$861$875.76 -1.5%Oct 23, 2026
Wells FargoAnalyst unavailable$1,336$875.76 +52.8%Oct 23, 2026
Stifel NicolausAlex Thompson$1,200$886.47 +37.3%Oct 22, 2026
See 84 more

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Company context

Snapshot as of publication

argenx SE, a biotechnology company established in Amsterdam, the Netherlands, in 2008, is dedicated to developing innovative therapies primarily for autoimmune diseases. The company's operations span across key global markets, including the United States, Japan, Europe, the Middle East, Africa, and China. Its leading investigational therapy is efgartigimod, which is being developed to address a broad range of conditions. These include generalized myasthenia gravis, immune thrombocytopenia, pemphigus vulgaris, chronic inflammatory demyelinating polyneuropathy, thyroid eye disease, bullous pemphigoid, myositis, primary Sjögren's syndrome, post-COVID postural orthostatic tachycardia syndrome, membranous nephropathy, lupus nephropathy, ANCA-associated vasculitis, and antibody-mediated rejection. Also noted in connection with its lead product efforts is ENHANZE SC. The company's extensive development pipeline features several other promising candidates.…

Historical context

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Sources

  1. Earnings call transcript and parsed analysis · 2026-05-11T10:29:34.698584+00:00
  2. FN2 earnings calendar · 2025-02-20T12:35:15.052560+00:00
  3. Polygon adjusted daily market bars · 2026-10-26T15:20:44.101008+00:00
  4. Financial Modeling Prep analyst price-target consensus and quote snapshot · 2026-10-26T15:20:44.097962+00:00

Methodology

Reported and consensus figures come from FN2's earnings event records. Market reaction and volume are calculated from daily adjusted bars around the event; abnormal move subtracts the SPY move over the same window.

Analyst target low, average, and high values are derived at request time from each named analyst's latest persisted FMP target. The current-price marker comes from FN2's persisted market snapshot. They are sell-side estimates, not an FN2 valuation or recommendation.

Transcript intelligence is a structured synthesis of the current and prior earnings-call analyses. Missing values stay missing and are never estimated.

By FN2 Research · Updated · As of 2026-10-26. For educational purposes only; not investment advice.