Amgen Inc. · AMGN · FY2023 Q4 · Calendar Q1 2024

Amgen: Horizon Integration Broadens Growth, Pipeline Execution Matters

The analysis supports a constructive but conditional view of Amgen’s growth trajectory: resilient volume and the Horizon rare-disease platform strengthen the earnings base, while pipeline execution, pricing, leverage, and regulatory outcomes determine whether that momentum persists.

Reported After market closeNASDAQHealthcare $234.65B market cap
100quality score

Earnings scorecard

Reported versus consensus
Reported EPS $4.71 Consensus $4.59
EPS surprise +2.6% Reported versus consensus
Reported revenue $8.20B Consensus $8.13B
Revenue surprise +0.9% Reported versus consensus

Market reaction

event-close to next-session close
Stock move -6.4% Event window
SPY move +0.8% Same window
Abnormal move -7.2% Stock minus SPY
Volume 3.2× Versus trailing sessions
Subsequent drift -7.8% Up to 20 sessions
AMGNSPY benchmark

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Transcript intelligence

What changed

Horizon is now fully reflected as a fourth commercial pillar, while management highlighted a broader set of pipeline milestones and continued investment in manufacturing and AI. The focus has shifted from acquisition completion toward integration benefits and delivery against the development roadmap.

Guidance delta

Management maintained a confident outlook, with the current analysis pointing to continued revenue expansion, higher operating margins, and substantial pipeline investment.

Key takeaways

  • The Horizon acquisition is now operating as a fourth growth pillar, expanding Amgen’s rare-disease platform.
  • Management emphasized broad-based volume growth and progress across obesity, oncology, inflammation, and rare-disease programs.
  • The outlook depends on pipeline milestones, manufacturing expansion, payer access, and execution amid pricing pressure and acquisition-related debt.

Management priorities

  • Advance MariTide and other late-stage pipeline programs.
  • Expand TEZSPIRE, TEPEZZA, and UPLIZNA across indications and geographies.
  • Complete Ohio and North Carolina manufacturing capacity and broaden AI use across the business.
  • Support patient access and payer coverage for growth products.

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Earnings History

Estimate Beat Miss Match
AMGN EPS earnings history estimate and actual scatter chart 9 reported fiscal quarters and 3 future estimate-only quarters. Q4 '23 estimate $4.59 Q4 '23 actual $4.71, beat Q1 '24 estimate $3.88 Q1 '24 actual $3.96, beat Q2 '24 estimate $4.98 Q2 '24 actual $4.97, match Q3 '24 estimate $5.11 Q3 '24 actual $5.58, beat Q2 '25 estimate $5.28 Q2 '25 actual $6.02, beat Q3 '25 estimate $5.02 Q3 '25 actual $5.64, beat Q4 '25 estimate $4.73 Q4 '25 actual $5.29, beat Q1 '26 estimate $4.77 Q1 '26 actual $5.15, beat Q2 '26 estimate $5.62 Q2 '26 actual $6.29, beat Q3 '26 estimate $5.76 Q4 '26 estimate $5.77 Q1 '27 estimate $5.42
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Analyst Consensus ?

ConsensusHold41 ratings
Bullish2253.7%
Neutral1639.0%
Bearish37.3%

Analyst 52W Price Targets

$436.69Current
$182Low
$348.75Average
$500High

Latest persisted target per named analyst; persisted current price from FN2's market snapshot as of Oct 16, 2026. Not an FN2 forecast.

Firm-level rating actions

FMP grade actions identify the grading firm, not a named analyst.

FirmRatingPrior ratingActionDate
Guggenheim Neutral NeutralMaintainOct 13, 2026
Wells Fargo Equal Weight Equal WeightMaintainOct 12, 2026
BMO Capital Market Perform Market PerformMaintainOct 12, 2026
UBS Buy BuyMaintainOct 9, 2026
RBC Capital Outperform OutperformMaintainOct 8, 2026
Show 36 more rating actions

Named analyst price targets

Upside is calculated against the persisted current price $436.69. FMP does not supply a rating on these named-analyst rows.

FirmAnalyst52W targetPrice when postedUpsideDate
GuggenheimVamil Divan$378$417.57 -13.4%Oct 13, 2026
BMO CapitalAnalyst unavailable$415$415.8 -5.0%Oct 12, 2026
Wells FargoAnalyst unavailable$430$414.87 -1.5%Oct 12, 2026
RBC CapitalAnalyst unavailable$430$407.58 -1.5%Oct 8, 2026
Cantor FitzgeraldCarter Gould$440$413.08 +0.8%Oct 8, 2026
See 110 more

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Company context

Snapshot as of publication

Amgen Inc., established in 1980 and headquartered in Thousand Oaks, California, is a global biotechnology leader focused on discovering, developing, manufacturing, and delivering groundbreaking human medicines. The company's scientific endeavors span several critical therapeutic categories, including inflammatory conditions, oncology and hematology, bone health, cardiovascular diseases, nephrology, and neuroscience. Its extensive portfolio features a range of significant pharmaceutical products. Notable examples include Enbrel, prescribed for conditions like plaque psoriasis, rheumatoid arthritis, and psoriatic arthritis; Neulasta, which helps cancer patients by reducing the risk of infection linked to a low white blood cell count; Prolia, utilized in postmenopausal women to combat osteoporosis; and Xgeva, designed to prevent skeletal-related complications. Otezla offers relief for adult patients suffering from plaque psoriasis, psoriatic arthritis, and oral ulcers associated with Behçet's disease.…

Historical context

All AMGN earnings

Latest beats and misses

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Sources

  1. Earnings call transcript and parsed analysis · 2026-05-11T10:29:34.698584+00:00
  2. FN2 earnings calendar · 2024-11-11T06:39:45.180704+00:00
  3. Polygon adjusted daily market bars · 2026-10-16T12:10:43.772218+00:00
  4. Financial Modeling Prep analyst price-target consensus and quote snapshot · 2026-10-16T12:10:43.769423+00:00

Methodology

Reported and consensus figures come from FN2's earnings event records. Market reaction and volume are calculated from daily adjusted bars around the event; abnormal move subtracts the SPY move over the same window.

Analyst target low, average, and high values are derived at request time from each named analyst's latest persisted FMP target. The current-price marker comes from FN2's persisted market snapshot. They are sell-side estimates, not an FN2 valuation or recommendation.

Transcript intelligence is a structured synthesis of the current and prior earnings-call analyses. Missing values stay missing and are never estimated.

By FN2 Research · Updated · As of 2026-10-16. For educational purposes only; not investment advice.