AbbVie Inc. · ABBV · FY2026 Q1 · Calendar Q2 2026

AbbVie Beats Q1 Estimates on Skyrizi-Rinvoq Strength, Raises Full-Year EPS Guidance

AbbVie's Q1 FY2026 results reinforce the post-Humira transition thesis: Skyrizi and Rinvoq are delivering double-digit growth and gaining market share across psoriatic disease, IBD, and emerging dermatology indications, more than offsetting ongoing biosimilar erosion of Humira. With a raised full-year adjusted EPS guidance range of $14.08-$14.28, a deep pipeline spanning obesity (ABBV-295), oncology (Temab-A, PD-1/VEGF bispecifics), and neuroscience (tavapadon, VYALEV), and significant manufacturing capacity investments, management signaled confidence in sustained growth. The stock's +3.1% earnings-day move and +7.2% subsequent drift suggest the market is endorsing the beat-and-raise narrative.

Reported Before market openNYSEHealthcare $453.92B market cap
90quality score

Earnings scorecard

Reported versus consensus
Reported EPS $2.65 Consensus $2.59
EPS surprise +2.3% Reported versus consensus
Reported revenue $15.00B Consensus $14.72B
Revenue surprise +1.9% Reported versus consensus

Market reaction

prior-close to event-session close
Stock move +3.1% Event window
SPY move -0.0% Same window
Abnormal move +3.2% Stock minus SPY
Volume 1.6× Versus trailing sessions
Subsequent drift +7.2% Up to 20 sessions
ABBVSPY benchmark

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What changed

Several developments were new or incremental this quarter. AbbVie announced a $1.4 billion manufacturing campus in North Carolina and a $380 million investment in two new plants in North Chicago, materially expanding production capacity for high-growth therapeutic areas. Early-stage data for the long-acting amylin analog ABBV-295 showed approximately 10% weight loss in a 12-week study. The company closed the Remagen agreement, adding a PD-1/VEGF bispecific antibody to its oncology pipeline. Full-year EPS guidance was raised, and the capex outlook moved higher to reflect the new manufacturing commitments.

Guidance delta

Full-year adjusted EPS guidance was raised to $14.08-$14.28. Management's guidance sentiment was characterized as raised, and the capex outlook is increasing, reflecting the $1.4B North Carolina and $380M North Chicago manufacturing investments. Specific prior guidance levels were not available in the supplied transcript analysis for a precise before-after comparison.

Key takeaways

  • Q1 net revenue of $15.0B grew 12.4% year-over-year with adjusted EPS of $2.65, beating consensus estimates of $2.59 EPS and $14.72B revenue.
  • Immunology led growth as Skyrizi and Rinvoq delivered double-digit sales increases and gained market share in psoriatic disease, IBD, and emerging dermatology indications.
  • Full-year adjusted EPS guidance was raised to $14.08-$14.28, reflecting confidence in the revenue trajectory.
  • Pipeline milestones included early ABBV-295 obesity data (~10% weight loss in 12 weeks), Phase III Temab-A readouts expected at ASCO, and the closing of the Remagen PD-1/VEGF bispecific agreement.
  • AbbVie announced $1.4B for a North Carolina manufacturing campus and $380M for North Chicago plants, signaling long-term capacity investment in high-growth therapeutic areas.

Management priorities

  • Sustain Skyrizi and Rinvoq market share gains and label expansions, including subcutaneous induction for Crohn's disease with a U.S. regulatory decision expected later in 2026.
  • Advance the obesity pipeline with ABBV-295 toward further clinical development and regulatory filing.
  • Launch tavapadon for Parkinson's disease later in 2026.
  • Execute oncology combination programs, including Temab-A Phase III readouts in head-and-neck and ovarian cancers at ASCO.
  • Build out manufacturing capacity with new campuses in North Carolina and Illinois.

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Earnings History

Estimate Beat Miss Match
ABBV EPS earnings history estimate and actual scatter chart 9 reported fiscal quarters and 3 future estimate-only quarters. Q1 '24 estimate $2.26 Q1 '24 actual $2.31, beat Q2 '24 estimate $2.57 Q2 '24 actual $2.65, beat Q3 '24 estimate $2.92 Q3 '24 actual $3.00, beat Q2 '25 estimate $2.88 Q2 '25 actual $2.97, beat Q3 '25 estimate $1.77 Q3 '25 actual $1.86, beat Q4 '25 estimate $2.65 Q4 '25 actual $2.71, beat Q1 '26 estimate $2.59 Q1 '26 actual $2.65, beat Q2 '26 estimate $3.61 Q2 '26 actual $3.65, beat Q3 '26 estimate $3.73 Q4 '26 estimate $4.00 Q1 '27 estimate $3.32
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Analyst Consensus ?

ConsensusBuy44 ratings
Bullish3170.4%
Neutral1227.3%
Bearish12.3%

Analyst 52W Price Targets

$286.74Current
$127Low
$219.61Average
$325High

Latest persisted target per named analyst; persisted current price from FN2's market snapshot as of Oct 27, 2026. Not an FN2 forecast.

Firm-level rating actions

FMP grade actions identify the grading firm, not a named analyst.

FirmRatingPrior ratingActionDate
Goldman Sachs Neutral NeutralMaintainOct 23, 2026
Barclays Overweight OverweightMaintainOct 21, 2026
RBC Capital Outperform OutperformMaintainOct 13, 2026
UBS Neutral NeutralMaintainOct 9, 2026
Guggenheim Buy BuyMaintainOct 9, 2026
Show 39 more rating actions

Named analyst price targets

Upside is calculated against the persisted current price $286.74. FMP does not supply a rating on these named-analyst rows.

FirmAnalyst52W targetPrice when postedUpsideDate
Goldman SachsAnalyst unavailable$294$284.89 +2.5%Oct 23, 2026
BarclaysAnalyst unavailable$325$289 +13.3%Oct 21, 2026
Cantor FitzgeraldCarter Gould$290$271.36 +1.1%Oct 8, 2026
Morgan StanleyAnalyst unavailable$310$271.89 +8.1%Oct 7, 2026
ScotiabankLouise Chen$320$265.21 +11.6%Oct 6, 2026
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Company context

Snapshot as of publication

AbbVie Inc. is a global biopharmaceutical company dedicated to the discovery, development, manufacturing, and commercialization of advanced medicines. Its extensive therapeutic portfolio encompasses several key areas: Immunology and Inflammation: Leading products include HUMIRA, an injectable therapy for autoimmune and intestinal Behçet's diseases; SKYRIZI, which addresses moderate to severe plaque psoriasis in adults; and RINVOQ, a JAK inhibitor for moderate to severe active rheumatoid arthritis in adult patients. Oncology and Hematology: For blood cancers, AbbVie provides IMBRUVICA and VENCLEXTA (a BCL-2 inhibitor), both indicated for adult patients with chronic lymphocytic leukemia (CLL) and small lymphocytic lymphoma (SLL). Virology: MAVYRET offers a treatment option for individuals with chronic HCV genotype 1-6 infection. Gastroenterology and Endocrinology: The company supplies CREON, an enzyme replacement therapy for exocrine pancreatic insufficiency, and Synthroid, used to manage hypothyroidism.…

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Sources

  1. Earnings call transcript and parsed analysis · 2026-05-11T10:29:34.698584+00:00
  2. FN2 earnings calendar · 2026-07-26T00:37:12.209961+00:00
  3. Polygon adjusted daily market bars · 2026-07-28T07:21:27.729119+00:00
  4. Financial Modeling Prep analyst price-target consensus and quote snapshot · 2026-07-28T07:21:27.725208+00:00

Methodology

Reported and consensus figures come from FN2's earnings event records. Market reaction and volume are calculated from daily adjusted bars around the event; abnormal move subtracts the SPY move over the same window.

Analyst target low, average, and high values are derived at request time from each named analyst's latest persisted FMP target. The current-price marker comes from FN2's persisted market snapshot. They are sell-side estimates, not an FN2 valuation or recommendation.

Transcript intelligence is a structured synthesis of the current and prior earnings-call analyses. Missing values stay missing and are never estimated.

By FN2 Research · Updated · As of 2026-07-28. For educational purposes only; not investment advice.