Incyte Corporation · INCY · FY2026 Q2 · Calendar Q3 2026

Incyte raises guidance as launches and pipeline catalysts advance

Incyte’s Q2 update strengthens the near-term growth case through broad portfolio growth, higher guidance, product launches and pipeline progress. The thesis still depends on launch execution, reimbursement conditions and regulatory delivery.

Reported Before market openNASDAQHealthcare $25.27B market cap
100quality score

Earnings scorecard

Reported versus consensus
Reported EPS $3.09 Consensus $2.15
EPS surprise +43.7% Reported versus consensus
Reported revenue $1.67B Consensus $1.50B
Revenue surprise +11.3% Reported versus consensus

Market reaction

prior-close to event-session close
Stock move +9.3% Event window
SPY move +0.2% Same window
Abnormal move +9.1% Stock minus SPY
Volume 3.6× Versus trailing sessions
Subsequent drift -0.2% Up to 20 sessions
INCYSPY benchmark

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What changed

Compared with the prior quarter, management reported stronger portfolio growth, raised full-year guidance, advanced Jakafi XR and Opzelura launches, added Vega’s latarcibart, and announced a Halozyme collaboration for 989.

Guidance delta

Management raised full-year net-sales and operating-expense guidance; Opzelura sales guidance increased to $1.05-$1.10 billion.

Key takeaways

  • Q2 revenue increased 38% year over year to $1.67 billion.
  • Jakafi XR launch is on track, with full-year sales expected at $40-$50 million.
  • Opzelura guidance rose after the CMS settlement improved its gross-to-net profile.
  • Vega added latarcibart, while Halozyme collaboration supports subcutaneous 989 development.

Management priorities

  • Execute the Jakafi XR rollout and expand Opzelura internationally.
  • Advance Phase III programs for 989, 734, 890 and latarcibart.
  • Pursue regulatory milestones and continue selective M&A scouting.
  • Expand in Europe, Japan and other international markets.

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Earnings History

Estimate Beat Miss Match
INCY EPS earnings history estimate and actual scatter chart 9 reported fiscal quarters and 3 future estimate-only quarters. Q1 '24 estimate $0.84 Q1 '24 actual $0.64, miss Q2 '24 estimate $0.78 Q2 '24 actual $-1.82, miss Q3 '24 estimate $1.12 Q3 '24 actual $1.07, miss Q2 '25 estimate $1.39 Q2 '25 actual $1.57, beat Q3 '25 estimate $1.66 Q3 '25 actual $2.26, beat Q4 '25 estimate $1.90 Q4 '25 actual $1.80, miss Q1 '26 estimate $1.34 Q1 '26 actual $1.81, beat Q2 '26 estimate $2.15 Q2 '26 actual $3.09, beat Q3 '26 estimate $-2.83 Q4 '26 estimate $2.12 Q1 '27 estimate $1.70
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Analyst Consensus ?

ConsensusBuy44 ratings
Bullish2352.3%
Neutral2045.4%
Bearish12.3%

Analyst 52W Price Targets

$124.65Current
$48Low
$108.05Average
$200High

Latest persisted target per named analyst; persisted current price from FN2's market snapshot as of Sep 22, 2026. Not an FN2 forecast.

Firm-level rating actions

FMP grade actions identify the grading firm, not a named analyst.

FirmRatingPrior ratingActionDate
HC Wainwright & Co. Buy BuyMaintainAug 20, 2026
Piper Sandler Overweight OverweightMaintainAug 17, 2026
Mizuho Outperform OutperformMaintainAug 4, 2026
Leerink Partners Outperform OutperformMaintainAug 3, 2026
RBC Capital Sector Perform Sector PerformMaintainJul 29, 2026
Guggenheim Buy BuyMaintainJul 29, 2026
BMO Capital Market Perform Market PerformMaintainJul 29, 2026
Barclays Overweight OverweightMaintainJul 29, 2026
Morgan Stanley Equal Weight Equal WeightMaintainJul 23, 2026
JP Morgan Neutral NeutralMaintainJul 23, 2026
UBS Neutral NeutralMaintainJun 26, 2026
Truist Securities Hold HoldMaintainJun 22, 2026
Stifel Buy BuyMaintainApr 29, 2026
Oppenheimer Perform PerformMaintainApr 29, 2026
Jefferies Hold BuyDowngradeMar 16, 2026
Evercore ISI Group In Line In LineMaintainMar 5, 2026
Wells Fargo Equal Weight Equal WeightMaintainFeb 11, 2026
TD Cowen Buy BuyMaintainJan 13, 2026
B of A Securities Buy BuyMaintainSep 4, 2025
Citigroup Buy BuyMaintainJul 30, 2025
William Blair Market Perform OutperformDowngradeMar 18, 2025
Citizens Capital Markets Market Perform Market PerformMaintainMar 11, 2025
JMP Securities Market Perform Market PerformMaintainFeb 11, 2025
Cantor Fitzgerald Neutral NeutralMaintainJan 10, 2025
Goldman Sachs Neutral NeutralMaintainOct 30, 2024
Deutsche Bank Hold HoldMaintainAug 1, 2024
SVB Leerink Underperform UnderperformMaintainMar 20, 2023
Credit Suisse Buy BuyMaintainFeb 16, 2023
Cowen & Co. Outperform OutperformMaintainFeb 8, 2023
Benchmark Buy HoldUpgradeJul 20, 2021
Guggenheim Securities Neutral BuyDowngradeJan 2, 2020
Nomura Buy BuyMaintainJul 31, 2019
Stifel Nicolaus Hold HoldMaintainApr 11, 2019
Argus Research Buy BuyMaintainFeb 25, 2019
Argus Buy BuyMaintainFeb 25, 2019
Gabelli & Co. Buy HoldUpgradeJan 24, 2019
Leerink Swann Perform Market PerformMaintainSep 25, 2018
Raymond James Outperform Market PerformUpgradeSep 11, 2017
PiperJaffray Neutral OverweightDowngradeApr 17, 2017
SunTrust Robinson Humphrey Buy BuyMaintainAug 5, 2016
Brean Capital Buy BuyMaintainFeb 12, 2016
Bank of America Buy BuyMaintainMay 29, 2015
Lazard Buy NeutralUpgradeJan 14, 2013
Canaccord Genuity Buy BuyMaintainApr 26, 2012
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Named analyst price targets

Upside is calculated against the persisted current price $124.65. FMP does not supply a rating on these named-analyst rows.

FirmAnalyst52W targetPrice when postedUpsideDate
Canaccord GenuityAnalyst unavailable$152$128.47 +21.9%Aug 20, 2026
Piper SandlerAllison Bratzel$130$120.16 +4.3%Aug 17, 2026
BernsteinAnalyst unavailable$104$120.77 -16.6%Aug 13, 2026
Leerink PartnersAndrew Berens$155$119.52 +24.3%Aug 3, 2026
RBC CapitalBrian Abrahams$109$126.69 -12.6%Jul 29, 2026
BMO CapitalAnalyst unavailable$130$128.83 +4.3%Jul 29, 2026
GuggenheimWhitney Ljem$150$129.93 +20.3%Jul 29, 2026
Morgan StanleyAnalyst unavailable$119$129.93 -4.5%Jul 29, 2026
H.C. WainwrightAnalyst unavailable$150$129.93 +20.3%Jul 29, 2026
BarclaysAnalyst unavailable$139$129.93 +11.5%Jul 29, 2026
Stifel NicolausStephen Willey$145$130.08 +16.3%Jul 28, 2026
OppenheimerAnalyst unavailable$120$130.08 -3.7%Jul 28, 2026
Morgan StanleyAnalyst unavailable$104$116.12 -16.6%Jul 23, 2026
BarclaysAnalyst unavailable$134$114.23 +7.5%Jul 14, 2026
BMO CapitalAnalyst unavailable$112$115.04 -10.1%Jul 13, 2026
RBC CapitalAnalyst unavailable$99$115.62 -20.6%Jul 7, 2026
UBSAnalyst unavailable$113$107.53 -9.3%Jun 26, 2026
Truist FinancialAnalyst unavailable$105$103.21 -15.8%Jun 22, 2026
BMO CapitalEvan David Seigerman$94$98.22 -24.6%Jun 22, 2026
H.C. WainwrightMitchell Kapoor$140$103.23 +12.3%Jun 10, 2026
Stifel NicolausStephen Willey$123$103.07 -1.3%Jun 9, 2026
OppenheimerJay Olson$107$100.64 -14.2%Jun 8, 2026
BernsteinAnalyst unavailable$99$97.41 -20.6%May 21, 2026
OppenheimerAnalyst unavailable$90$97.74 -27.8%Apr 29, 2026
BarclaysAnalyst unavailable$117$101.16 -6.1%Feb 18, 2026
Morgan StanleyAnalyst unavailable$102$98.45 -18.2%Feb 11, 2026
Stifel NicolausStephen Willey$120$100.05 -3.7%Feb 11, 2026
Piper SandlerAllison Bratzel$110$102.76 -11.8%Feb 6, 2026
H.C. WainwrightAnalyst unavailable$135$102.6 +8.3%Feb 5, 2026
BarclaysAnalyst unavailable$116$100.92 -6.9%Feb 4, 2026
Wells FargoAnalyst unavailable$107$106.21 -14.2%Jan 20, 2026
Goldman SachsAnalyst unavailable$90$110.57 -27.8%Jan 8, 2026
Stifel NicolausStephen Willey$119$101.79 -4.5%Jan 5, 2026
Truist FinancialSrikripa Devarakonda$103$100.91 -17.4%Dec 24, 2025
Morgan StanleyAnalyst unavailable$92$96.46 -26.2%Dec 8, 2025
Wells FargoDerek Archila$116$102.52 -6.9%Dec 8, 2025
Mizuho SecuritiesSalim Syed$121$102.52 -2.9%Dec 8, 2025
BarclaysAnalyst unavailable$115$102.06 -7.7%Nov 24, 2025
Piper SandlerAllison Bratzel$102$102.35 -18.2%Nov 4, 2025
Truist FinancialAnalyst unavailable$93$90.35 -25.4%Oct 29, 2025
RBC CapitalAnalyst unavailable$84$91.65 -32.6%Oct 29, 2025
Wells FargoDerek Archila$97$92.02 -22.2%Oct 29, 2025
BarclaysPeter Lawson$101$91.65 -19.0%Oct 29, 2025
UBSAnalyst unavailable$68$77.55 -45.4%Jul 30, 2025
RBC CapitalAnalyst unavailable$67$67.26 -46.2%Jun 23, 2025
GuggenheimAnalyst unavailable$92$60 -26.2%Mar 18, 2025
Seaport GlobalAaron Kessler$200$73 +60.4%Oct 30, 2024
OppenheimerJay Olson$82$73.6 -34.2%Oct 30, 2024
CitigroupDavid Lebowitz$97$73.6 -22.2%Oct 30, 2024
JefferiesKelly Shi$84$73.6 -32.6%Oct 29, 2024
Bank of America SecuritiesTazeen Ahmad$90$73.6 -27.8%Oct 29, 2024
Wolfe ResearchAndy Chen$84$66.1 -32.6%Sep 30, 2024
Bank of America SecuritiesTazeen Ahmad$68$63.56 -45.4%Sep 16, 2024
Goldman SachsSalveen Richter$60$63.56 -51.9%Sep 16, 2024
CitigroupDavid Lebowitz$92$62.16 -26.2%Aug 18, 2024
RBC CapitalBrian Abrahams$66$65.7 -47.1%Jul 31, 2024
OppenheimerJay Olson$81$68.57 -35.0%Jul 26, 2024
BMO CapitalEvan Seigerman$48$60.87 -61.5%Jul 2, 2024
Deutsche BankJames Shin$55$58.2 -55.9%May 23, 2024
BMO CapitalEvan David Seigerman$52$52.05 -58.3%Apr 30, 2024
Argus ResearchJasper Hellweg$70$50.48 -43.8%Apr 25, 2024
Cowen & Co.Analyst unavailable$100$80.38 -19.8%Feb 8, 2023
Wells FargoAnalyst unavailable$75$79.74 -39.8%Jan 3, 2023
OppenheimerJay Olson$98$73.99 -21.4%Aug 15, 2022
Leerink PartnersAnalyst unavailable$63$81.36 -49.5%Jul 20, 2022
Morgan StanleyAnalyst unavailable$76$78.94 -39.0%Apr 20, 2022
BMO CapitalEvan Seigerman$75$70.07 -39.8%Feb 8, 2022
GuggenheimMichael Schmidt$104$73.97 -16.6%Jan 3, 2022
Goldman SachsSalveen Richter$136$66.74 +9.1%Nov 24, 2021
OppenheimerJay Olson$109$66.79 -12.6%Nov 3, 2021
Cantor FitzgeraldAlethia Young$79$65.56 -36.6%Oct 15, 2021
Ladenburg Thalmann & Co.Aydin Huseynov$89$69.78 -28.6%Sep 23, 2021
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Company context

Snapshot as of publication

Incyte Corporation is a biopharmaceutical firm engaged in the research, development, and global marketing of its own innovative therapies. Its current product offerings include JAKAFI, prescribed for myelofibrosis and polycythemia vera; PEMAZYRE, a fibroblast growth factor receptor kinase inhibitor that targets oncogenic drivers in various liquid and solid tumor types; and ICLUSIG, a kinase inhibitor utilized for chronic myeloid leukemia and Philadelphia-chromosome positive acute lymphoblastic leukemia. Beyond its marketed drugs, Incyte's pipeline features several promising candidates. Among its clinical-stage assets are ruxolitinib, targeting steroid-refractory chronic graft-versus-host disease (GVHD), and itacitinib, which is undergoing Phase II/III trials for newly diagnosed chronic GVHD. Pemigatinib is also being investigated for conditions such as bladder cancer, cholangiocarcinoma, myeloproliferative syndrome, and other tumor types.…

Historical context

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Sources

  1. Earnings call transcript and parsed analysis · 2026-08-14T14:13:42.007402+00:00
  2. FN2 earnings calendar · 2026-09-02T01:23:14.593608+00:00
  3. Polygon adjusted daily market bars · 2026-09-22T02:50:50.469992+00:00
  4. Financial Modeling Prep analyst price-target consensus and quote snapshot · 2026-09-22T02:50:50.467195+00:00

Methodology

Reported and consensus figures come from FN2's earnings event records. Market reaction and volume are calculated from daily adjusted bars around the event; abnormal move subtracts the SPY move over the same window.

Analyst target low, average, and high values are derived at request time from each named analyst's latest persisted FMP target. The current-price marker comes from FN2's persisted market snapshot. They are sell-side estimates, not an FN2 valuation or recommendation.

Transcript intelligence is a structured synthesis of the current and prior earnings-call analyses. Missing values stay missing and are never estimated.

By FN2 Research · Updated . For educational purposes only; not investment advice.