Charles River Laboratories International, Inc. · CRL · FY2026 Q1 · Calendar Q2 2026

Charles River Beats Q1 Estimates as Cost Savings and NHP Internalization Drive Margin Story

Charles River's Q1 FY2026 beat on both EPS ($2.06 vs $1.96, +5.1%) and revenue ($995.8M vs $977.5M, +1.9%) marks an incremental improvement from the 1.6% organic revenue decline in 2025. Management reaffirmed 2026 guidance and shifted tone from cautious to confident, citing net book-to-bill above 1.0, high-single-digit proposal volume growth, and a $300M cumulative cost-savings program targeting 120-150 bps of operating margin expansion. The strategic narrative now centers on NHP supply internalization (K.F. Cambodia, Noveprim), portfolio reshaping (CDMO and Cell Solutions divested, PathoQuest acquired), and AI/NAMs as long-term growth drivers. The market response was muted -- a 0.28% abnormal return on elevated volume -- suggesting investors are waiting for the September Investor Day to validate the Pathway to Purpose strategy. The stock trades at $233.59, modestly above the analyst…

Reported Before market openNYSEHealthcare $11.30B market cap
100quality score

Company context

Snapshot as of publication

Charles River Laboratories International, Inc. operates as a contract research organization (CRO), providing essential preclinical services to the pharmaceutical and biotechnology industries. Its core business revolves around assisting clients with drug discovery, non-clinical development, and thorough safety testing, with its services extending globally across the United States, Europe, Canada, and the Asia Pacific region. The company organizes its diverse offerings into three principal segments: Research Models and Services (RMS), Discovery and Safety Assessment (DSA), and Manufacturing Solutions. 1. Research Models and Services (RMS): This division is a key supplier of high-quality rodent research models, including specially bred strains of rats and mice for experimental purposes. It also offers a comprehensive array of support services to help clients effectively utilize these models in their research and for the screening of potential non-clinical drug candidates.…

Earnings scorecard

Reported versus consensus
Reported EPS $2.06 Consensus $2
EPS surprise +5.1% Reported versus consensus
Reported revenue $995.8M Consensus $977.5M
Revenue surprise +1.9% Reported versus consensus

Earnings History

Estimate Beat Miss Match
CRL EPS earnings history estimate and actual scatter chart 8 reported fiscal quarters and 4 future estimate-only quarters. Q4 '23 estimate $2.39 Q4 '23 actual $2.46, beat Q1 '24 estimate $2.06 Q1 '24 actual $2.27, beat Q2 '24 estimate $2.39 Q2 '24 actual $2.80, beat Q3 '24 estimate $2.43 Q3 '24 actual $2.59, beat Q2 '25 estimate $2.50 Q2 '25 actual $3.12, beat Q3 '25 estimate $2.32 Q3 '25 actual $2.43, beat Q4 '25 estimate $2.33 Q4 '25 actual $2.39, beat Q1 '26 estimate $1.96 Q1 '26 actual $2.06, beat Q2 '26 estimate $2.72 Q3 '26 estimate $3.05 Q4 '26 estimate $3.25 Q1 '27 estimate $2.76

Analyst Consensus ?

ConsensusBuy36 ratings
Bullish2569.4%
Neutral1130.6%
Bearish00.0%

Analyst 52W Price Targets

$232.51Current
$151Low
$265.5Average
$465High

Latest persisted target per named analyst; persisted current price from FN2's market snapshot as of Jul 31, 2026. Not an FN2 forecast.

Firm-level rating actions

FMP grade actions identify the grading firm, not a named analyst.

FirmRatingPrior ratingActionDate
CLSA Hold OutperformDowngradeJul 20, 2026
Mizuho Neutral NeutralMaintainJul 13, 2026
Morgan Stanley Overweight OverweightMaintainJul 9, 2026
Evercore ISI Group Outperform OutperformMaintainMay 8, 2026
Barclays Overweight OverweightMaintainMay 8, 2026
JP Morgan Neutral NeutralMaintainApr 13, 2026
UBS Neutral NeutralMaintainFeb 25, 2026
TD Cowen Buy BuyMaintainFeb 20, 2026
Citigroup Buy BuyMaintainJan 16, 2026
Baird Outperform NeutralUpgradeNov 6, 2025
William Blair Outperform Market PerformUpgradeOct 6, 2025
Jefferies Buy HoldUpgradeSep 9, 2025
Redburn Atlantic Buy NeutralUpgradeMay 23, 2025
Goldman Sachs Neutral BuyDowngradeMar 21, 2025
B of A Securities Neutral NeutralMaintainDec 13, 2024
Argus Research Hold BuyDowngradeJun 28, 2024
Guggenheim Neutral BuyDowngradeFeb 15, 2024
Wells Fargo Overweight OverweightMaintainSep 22, 2023
Credit Suisse Outperform OutperformMaintainMay 12, 2023
Deutsche Bank Buy BuyMaintainJul 14, 2022
Keybanc Overweight OverweightMaintainMay 5, 2022
Stephens & Co. Overweight OverweightMaintainApr 7, 2022
Truist Securities Buy BuyMaintainMay 25, 2021
SunTrust Robinson Humphrey Buy BuyMaintainMay 8, 2020
Wolfe Research Outperform Peer PerformUpgradeFeb 18, 2020
CFRA Strong Buy Strong BuyMaintainFeb 11, 2020
Bank of America Neutral BuyDowngradeOct 18, 2019
RBC Capital Outperform OutperformMaintainNov 8, 2018
Raymond James Outperform OutperformMaintainNov 8, 2018
Argus Buy BuyMaintainAug 27, 2018
Mitsubishi UFJ Neutral NeutralMaintainApr 20, 2018
Gabelli & Co. Buy BuyMaintainApr 26, 2016
Edward Jones Buy NeutralUpgradeMay 4, 2015
Cantor Fitzgerald Buy BuyMaintainOct 1, 2013
Sterne Agee Buy BuyMaintainJun 11, 2013
ISI Group Neutral NeutralMaintainFeb 20, 2013
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Named analyst price targets

Upside is calculated against the persisted current price $232.51. FMP does not supply a rating on these named-analyst rows.

FirmAnalyst52W targetPrice when postedUpsideDate
Mizuho SecuritiesAnalyst unavailable$230$233.41 -1.1%Jul 13, 2026
Morgan StanleyAnalyst unavailable$260$223.96 +11.8%Jul 9, 2026
BNP ParibasAnalyst unavailable$250$226.79 +7.5%Jul 1, 2026
Morgan StanleyAnalyst unavailable$220$184.79 -5.4%Jun 17, 2026
CLSAAnalyst unavailable$219$181.34 -5.8%May 29, 2026
Robert W. BairdEric Coldwell$213$175.56 -8.4%May 8, 2026
Evercore ISIAnalyst unavailable$220$176.32 -5.4%May 8, 2026
Mizuho SecuritiesAnalyst unavailable$192$181.68 -17.4%May 8, 2026
BarclaysLuke Sergott$220$181.68 -5.4%May 8, 2026
BarclaysLuke Sergott$210$178.34 -9.7%Apr 14, 2026
RBC CapitalAnalyst unavailable$215$178.34 -7.5%Apr 14, 2026
Mizuho SecuritiesAnalyst unavailable$175$164.24 -24.7%Feb 20, 2026
Robert W. BairdEric Coldwell$193$158.18 -17.0%Feb 19, 2026
BarclaysLuke Sergott$200$158 -14.0%Feb 19, 2026
Robert W. BairdAnalyst unavailable$231$221.69 -0.6%Jan 13, 2026
Evercore ISIAnalyst unavailable$260$225.11 +11.8%Jan 13, 2026
Robert W. BairdEric Coldwell$224$219.49 -3.7%Jan 9, 2026
Mizuho SecuritiesAnn Hynes$215$215.51 -7.5%Jan 9, 2026
Mizuho SecuritiesAnalyst unavailable$200$195.98 -14.0%Dec 18, 2025
BarclaysAnalyst unavailable$215$192.97 -7.5%Dec 15, 2025
Morgan StanleyKallum Titchmarsh$185$176.09 -20.4%Dec 1, 2025
Argus ResearchAnalyst unavailable$200$166.73 -14.0%Nov 17, 2025
Mizuho SecuritiesAnn Hynes$174$174.95 -25.2%Oct 17, 2025
Evercore ISIElizabeth Anderson$200$181.18 -14.0%Oct 3, 2025
BarclaysLuke Sergott$195$170.48 -16.1%Oct 2, 2025
JefferiesAnalyst unavailable$195$157.38 -16.1%Sep 9, 2025
BarclaysLuke Sergott$205$193.14 -11.8%Oct 15, 2024
Redburn PartnersJamie Clark$151$192.97 -35.1%Oct 14, 2024
Mizuho SecuritiesAnn Hynes$210$206.44 -9.7%Sep 17, 2024
Deutsche BankJustin Bowers$240$200.34 +3.2%Aug 8, 2024
Robert W. BairdEric Coldwell$239$201.85 +2.8%Jul 10, 2024
BarclaysLuke Sergott$230$207.35 -1.1%Jun 28, 2024
Goldman SachsMatthew Sykes$290$216.12 +24.7%Jun 6, 2024
Evercore ISIElizabeth Anderson$265$230.09 +14.0%May 9, 2024
Evercore ISIElizabeth Anderson$300$270.95 +29.0%Apr 1, 2024
KeyBancDonald Hooker$300$257.51 +29.0%May 5, 2022
Wells FargoAnalyst unavailable$325$257.75 +39.8%Apr 25, 2022
JefferiesDavid Windley$280$273.03 +20.4%Apr 25, 2022
JefferiesDavid Windley$464$357.95 +99.6%Jan 11, 2022
Argus ResearchDavid Toung$440$377.51 +89.2%Nov 24, 2021
Cowen & Co.Daniel Brennan$465$417.45 +100.0%Aug 17, 2021
Credit SuisseKatie Tryhane$385$416.31 +65.6%Aug 4, 2021
J.P. MorganTycho Peterson$390$337.99 +67.7%May 28, 2021
GuggenheimSandy Draper$369$329.52 +58.7%May 25, 2021
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Market reaction

prior-close to event-session close
Stock move -0.0% Event window
SPY move -0.3% Same window
Abnormal move +0.3% Stock minus SPY
Volume 1.7× Versus trailing sessions
Subsequent drift -0.2% Up to 20 sessions
CRLSPY benchmark

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Transcript intelligence

What changed

EPS beat estimates by 5.1% ($2.06 vs $1.96) and revenue beat by 1.9% ($995.8M vs $977.5M). Management tone shifted from cautious to confident. Guidance sentiment moved from raised to maintained. Organic revenue decline improved to 1.5% from 1.6% in full-year 2025. PathoQuest acquisition closed, adding NGS-based quality-control testing to the NAMs portfolio. CDMO and Cell Solutions divestitures completed; sale of European discovery sites pending. Noveprim controlling-stake acquisition added, further internalizing NHP supply. $200M share repurchase executed. New Pathway to Purpose strategy announced with an Investor Day scheduled for September.

Guidance delta

Management reaffirmed full-year 2026 guidance: organic revenue flat to slightly negative, EPS $10.70-$11.20 (4-9% growth), operating margin up 20-50 bps. Guidance sentiment shifted from raised to maintained. The Q1 call provided additional margin-bridge detail, citing $100M of incremental cost savings and 120-150 bps of operating margin expansion from the $300M cumulative efficiency program.

Key takeaways

  • Q1 beat: EPS $2.06 vs $1.96 (+5.1%); revenue $995.8M vs $977.5M (+1.9%)
  • Organic revenue declined 1.5%, improving from 1.6% in full-year 2025
  • Net book-to-bill above 1.0 and high-single-digit proposal volume growth signal resilient demand
  • NHP supply internalization advanced through K.F. Cambodia and Noveprim acquisitions
  • Portfolio reshaping: CDMO and Cell Solutions divested, PathoQuest acquired, European discovery sites sale pending
  • $200M share repurchase executed

Management priorities

  • Host Investor Day in September to detail Pathway to Purpose strategy
  • Continue investing in AI, NAMs, and the Apollo cloud platform
  • Pursue additional M&A and strategic divestitures to sharpen the portfolio
  • Maintain disciplined capital allocation: share repurchases and debt repayment
  • Evaluate further geographic expansion, especially in China and broader Asia

Related earnings events

Healthcare

Sources

  1. Earnings call transcript and parsed analysis · 2026-05-11T10:29:34.698584+00:00
  2. FN2 earnings calendar · 2026-07-26T00:37:12.209961+00:00
  3. Polygon adjusted daily market bars · 2026-07-31T17:37:47.445980+00:00
  4. Financial Modeling Prep analyst price-target consensus and quote snapshot · 2026-07-31T17:37:47.442969+00:00

Methodology

Reported and consensus figures come from FN2's earnings event records. Market reaction and volume are calculated from daily adjusted bars around the event; abnormal move subtracts the SPY move over the same window.

Analyst target low, average, and high values are derived at request time from each named analyst's latest persisted FMP target. The current-price marker comes from FN2's persisted market snapshot. They are sell-side estimates, not an FN2 valuation or recommendation.

Transcript intelligence is a structured synthesis of the current and prior earnings-call analyses. Missing values stay missing and are never estimated.

By FN2 Research · Updated . For educational purposes only; not investment advice.