Bristol-Myers Squibb Company · BMY · FY2026 Q1 · Calendar Q2 2026

Bristol-Myers Squibb Beats Q1 Estimates as Oncology Pipeline Accelerates

Bristol-Myers Squibb posted a convincing Q1 2026 beat, with EPS of $1.58 (vs. $1.42 consensus, +11.3%) and revenue of $11.5B (vs. $10.9B consensus, +5.1%). Growth was anchored by double-digit expansion in early-life-cycle oncology assets Breyanzi and Opdualag, while the pipeline delivered tangible milestones: FDA breakthrough therapy designation for iberdomide (PDUFA August 17), positive Phase III interim data for an ADC in triple-negative breast cancer, and advancing late-stage readouts for Milvexian and oral CELMoDs. Management reaffirmed full-year guidance at the upper end of the range, backed by AI-driven R&D cycle-time reductions and disciplined capital allocation. The stock gained 5.2% on the report but has since drifted roughly 5.6% lower, and at $63.60 trades nearly in line with the $63.25 consensus target, suggesting the market is waiting for pipeline catalysts to materialize…

Reported Before market openNYSEHealthcare $127.75B market cap
90quality score

Earnings scorecard

Reported versus consensus
Reported EPS $1.58 Consensus $1.42
EPS surprise +11.3% Reported versus consensus
Reported revenue $11.49B Consensus $10.93B
Revenue surprise +5.1% Reported versus consensus

Market reaction

prior-close to event-session close
Stock move +5.2% Event window
SPY move +1.0% Same window
Abnormal move +4.2% Stock minus SPY
Volume 2.8× Versus trailing sessions
Subsequent drift -5.6% Up to 20 sessions
BMYSPY benchmark

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What changed

New this quarter: iberdomide received FDA breakthrough therapy designation and priority review with a PDUFA date of August 17; positive Phase III interim data for an ADC in previously treated triple-negative breast cancer was presented in China; a new focused study for Camzyos in non-obstructive hypertrophic cardiomyopathy was announced; and the company disclosed two acquisitions, one to obtain the Cobenfy asset and another adding an mRNA in-vivo platform to expand cell-therapy capabilities.

Guidance delta

Full-year 2026 guidance was reaffirmed. Management expressed confidence in meeting the upper end of the range, citing continued execution, AI-driven R&D efficiencies, and pipeline progress.

Key takeaways

  • Q1 revenue of $11.5B beat consensus by 5.1%, and EPS of $1.58 beat by 11.3%, driven by double-digit growth in Breyanzi and Opdualag.
  • Pipeline momentum is strong: iberdomide received FDA breakthrough therapy designation with an August 17 PDUFA date, and positive Phase III interim ADC data was presented in triple-negative breast cancer.
  • Full-year guidance was reaffirmed at the upper end of the range.
  • AI and laboratory automation initiatives aim to reduce drug development cycle times by 30%.
  • Business-development capital remains available for strategic acquisitions, as evidenced by two recent deals for Cobenfy and an mRNA in-vivo platform.

Management priorities

  • Present full Phase III data for ADCs and oral CELMoDs at ASCO.
  • Launch and expand market uptake of Pumitamig across multiple oncology indications.
  • Initiate a focused trial of Camzyos in non-obstructive hypertrophic cardiomyopathy.
  • Accelerate AI and laboratory automation investments to further reduce cycle times.
  • Continue evaluating strategic M&A opportunities aligned with core therapeutic areas.

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Earnings History

Estimate Beat Miss Match
BMY EPS earnings history estimate and actual scatter chart 9 reported fiscal quarters and 3 future estimate-only quarters. Q4 '23 estimate $1.52 Q4 '23 actual $1.70, beat Q1 '24 estimate $-4.41 Q1 '24 actual $-4.40, match Q2 '24 estimate $1.62 Q2 '24 actual $2.07, beat Q3 '24 estimate $1.49 Q3 '24 actual $1.80, beat Q2 '25 estimate $1.09 Q2 '25 actual $1.46, beat Q3 '25 estimate $1.52 Q3 '25 actual $1.63, beat Q4 '25 estimate $1.23 Q4 '25 actual $1.26, beat Q1 '26 estimate $1.42 Q1 '26 actual $1.58, beat Q2 '26 estimate $1.60 Q2 '26 actual $2.04, beat Q3 '26 estimate $1.10 Q4 '26 estimate $1.54 Q1 '27 estimate $1.38
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Analyst Consensus ?

ConsensusHold41 ratings
Bullish1843.9%
Neutral2151.2%
Bearish24.9%

1 unmapped firm rating excluded from the percentages.

Analyst 52W Price Targets

$61.61Previous close
$37Low
$64.18Average
$92High

Latest persisted target per named analyst; persisted previous close from FN2's market snapshot as of Oct 27, 2026. Not an FN2 forecast.

Firm-level rating actions

FMP grade actions identify the grading firm, not a named analyst.

FirmRatingPrior ratingActionDate
Wells Fargo Equal Weight Equal WeightMaintainOct 13, 2026
Cantor Fitzgerald Neutral NeutralMaintainOct 8, 2026
Morgan Stanley Underweight UnderweightMaintainOct 7, 2026
Leerink Partners Market Perform OutperformDowngradeOct 5, 2026
Piper Sandler Overweight OverweightMaintainSep 16, 2026
Show 37 more rating actions

Named analyst price targets

Upside is calculated against the persisted previous close $61.61. FMP does not supply a rating on these named-analyst rows.

FirmAnalyst52W targetPrice when postedUpsideDate
Piper SandlerAnalyst unavailable$78$61.48 +26.6%Oct 26, 2026
JefferiesAkash Tewari$76$57.58 +23.4%Oct 12, 2026
Cantor FitzgeraldCarter Gould$53$59.7 -14.0%Oct 8, 2026
Morgan StanleyTerence Flynn$41$59.7 -33.5%Oct 7, 2026
Leerink PartnersAnalyst unavailable$59$59.02 -4.2%Oct 5, 2026
See 55 more

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Company context

Snapshot as of publication

Bristol-Myers Squibb Company operates as a global biopharmaceutical entity, actively involved in the research, development, licensing, production, and worldwide commercialization of its medicinal portfolio. The company's therapeutic areas span hematology, oncology, cardiovascular health, immunology, fibrotic conditions, neuroscience, and infectious diseases like COVID-19. Its significant pharmaceutical offerings include Revlimid, an oral immunomodulatory agent for multiple myeloma, and Eliquis, an oral anticoagulant crucial for reducing stroke risk and systemic embolism in non-valvular atrial fibrillation, as well as treating deep vein thrombosis and pulmonary embolism. The portfolio also features Opdivo, utilized across various anti-cancer indications; Pomalyst/Imnovid, prescribed for multiple myeloma patients; and Orencia, targeting active rheumatoid arthritis and psoriatic arthritis in adults.…

Historical context

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Sources

  1. Earnings call transcript and parsed analysis · 2026-05-11T10:29:34.698584+00:00
  2. FN2 earnings calendar · 2026-07-26T00:37:12.209961+00:00
  3. Polygon adjusted daily market bars · 2026-07-28T22:21:10.411547+00:00
  4. Financial Modeling Prep analyst price-target consensus and quote snapshot · 2026-07-28T22:21:10.408544+00:00

Methodology

Reported and consensus figures come from FN2's earnings event records. Market reaction and volume are calculated from daily adjusted bars around the event; abnormal move subtracts the SPY move over the same window.

Analyst target low, average, and high values are derived at request time from each named analyst's latest persisted FMP target. The current-price marker comes from FN2's persisted market snapshot. They are sell-side estimates, not an FN2 valuation or recommendation.

Transcript intelligence is a structured synthesis of the current and prior earnings-call analyses. Missing values stay missing and are never estimated.

By FN2 Research · Updated · As of 2026-07-28. For educational purposes only; not investment advice.