Ascendis Pharma A/S · ASND · FY2026 Q2 · Calendar Q3 2026

Ascendis: Product Revenue More Than Doubled as YUVIWEL Launch Accelerated

The quarter supports a constructive operating thesis: demand for Ascendis's rare-endocrine products is accelerating, YUVIWEL is creating expansion beyond switches, and the company has substantial cash to fund pipeline and geographic growth. The main counterweights are regulatory and litigation uncertainty, titration execution, and reliance on early U.S. growth.

Reported Before market openNASDAQHealthcare $14.70B market cap
100quality score

Earnings scorecard

Reported versus consensus
Reported EPS $3.29 Consensus $1.71
EPS surprise +92.4% Reported versus consensus
Reported revenue $387.5M Consensus $376.8M
Revenue surprise +2.8% Reported versus consensus

Market reaction

prior-close to event-session close
Stock move -3.6% Event window
SPY move +0.7% Same window
Abnormal move -4.3% Stock minus SPY
Volume 2.1× Versus trailing sessions
Subsequent drift +7.0% Up to 20 sessions
ASNDSPY benchmark

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Transcript intelligence

What changed

Compared with the prior quarter, product momentum strengthened: YUVIWEL's U.S. launch was described as exceeding expectations, product revenue more than doubled year over year, and COACH combination-trial data added support for pipeline expansion. The company also reported EUR 812 million of cash and no bank or convertible debt, while guidance sentiment remained maintained.

Guidance delta

Maintained; management continues to target more than EUR 500 million of operating cash flow in 2026.

Key takeaways

  • Product revenue more than doubled year over year, led by YORVIPATH, SKYTROFA and the U.S. YUVIWEL launch.
  • Management said YUVIWEL is expanding the achondroplasia market beyond switch patients.
  • COACH combination-trial data showed arm-span gains above typical limb-lengthening surgery outcomes.
  • The balance sheet remains a key support, with EUR 812 million of cash and no bank or convertible debt.

Management priorities

  • Expand YUVIWEL across additional U.S. and European markets and pursue early-access programs.
  • Advance YORVIPATH label expansions, including higher doses and additional age groups.
  • Start Phase III programs for TransCon Growth Hormone and the COACH combination trial.
  • Continue annual IND filings and geographic expansion through partners.

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Earnings History

Estimate Beat Miss Match
ASND EPS earnings history estimate and actual scatter chart 8 reported fiscal quarters and 4 future estimate-only quarters. Q4 '23 estimate $-2.15 Q4 '23 actual $-1.66, beat Q1 '24 estimate $-1.57 Q1 '24 actual $-2.48, miss Q2 '24 estimate $-1.54 Q2 '24 actual $-2.05, miss Q2 '25 estimate $-1.42 Q2 '25 actual $-0.93, beat Q3 '25 estimate $-0.41 Q3 '25 actual $-1.17, miss Q4 '25 estimate $-0.06 Q4 '25 actual $-0.64, miss Q1 '26 estimate $0.19 Q1 '26 actual $0.32, beat Q2 '26 estimate $1.71 Q2 '26 actual $3.29, beat Q3 '26 estimate $0.82 Q4 '26 estimate $1.10 Q1 '27 estimate $1.73 Q2 '27 estimate $2.18

Analyst Consensus ?

ConsensusBuy26 ratings
Bullish2492.3%
Neutral27.7%
Bearish00.0%

Analyst 52W Price Targets

$239.18Current
$136Low
$272.3Average
$344High

Latest persisted target per named analyst; persisted current price from FN2's market snapshot as of Sep 21, 2026. Not an FN2 forecast.

Firm-level rating actions

FMP grade actions identify the grading firm, not a named analyst.

FirmRatingPrior ratingActionDate
Raymond James Outperform Strong BuyDowngradeSep 15, 2026
Oppenheimer Outperform OutperformMaintainSep 2, 2026
Wedbush Outperform OutperformMaintainSep 1, 2026
Morgan Stanley Overweight OverweightMaintainSep 1, 2026
Stifel Buy BuyMaintainAug 31, 2026
Jefferies Buy BuyMaintainAug 31, 2026
HC Wainwright & Co. Buy BuyMaintainAug 31, 2026
B of A Securities Buy BuyMaintainAug 31, 2026
TD Cowen Buy BuyMaintainAug 14, 2026
RBC Capital Outperform OutperformMaintainAug 14, 2026
Barclays Overweight OverweightMaintainAug 14, 2026
Evercore ISI Group Outperform OutperformMaintainMay 15, 2026
Wells Fargo Overweight OverweightMaintainMay 8, 2026
Cantor Fitzgerald Overweight OverweightMaintainOct 13, 2025
JP Morgan Overweight OverweightMaintainOct 9, 2025
UBS Buy BuyMaintainAug 8, 2025
Citigroup Buy BuyMaintainAug 8, 2025
Goldman Sachs Buy BuyMaintainFeb 13, 2025
Credit Suisse Neutral NeutralMaintainApr 28, 2023
SVB Leerink Outperform OutperformMaintainJan 17, 2023
Cowen & Co. Perform Market PerformMaintainJan 6, 2022
Canaccord Genuity Buy BuyMaintainJun 1, 2021
Berenberg Buy BuyMaintainDec 17, 2020
Leerink Swann Outperform Market PerformUpgradeJan 24, 2019
Stifel Nicolaus Buy BuyMaintainAug 30, 2018
Bank of America Buy BuyMaintainJan 25, 2018
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Named analyst price targets

Upside is calculated against the persisted current price $239.18. FMP does not supply a rating on these named-analyst rows.

FirmAnalyst52W targetPrice when postedUpsideDate
UBSAnalyst unavailable$344$239.77 +43.8%Sep 16, 2026
Raymond JamesMartin Auster$287$264.92 +20.0%Sep 15, 2026
H.C. WainwrightAnalyst unavailable$344$260.81 +43.8%Sep 10, 2026
OppenheimerLeland Gershell$312$260.25 +30.4%Sep 1, 2026
Morgan StanleyMaxwell Skor$273$263.04 +14.1%Sep 1, 2026
JefferiesAnalyst unavailable$330$265.26 +38.0%Aug 31, 2026
Stifel NicolausAnalyst unavailable$326$265.32 +36.3%Aug 31, 2026
UBSAnalyst unavailable$345$247.91 +44.2%Aug 31, 2026
H.C. WainwrightAnalyst unavailable$345$250.25 +44.2%Aug 27, 2026
BMO CapitalAnalyst unavailable$319$248.85 +33.4%Aug 18, 2026
RBC CapitalLuca Issi$290$247.06 +21.2%Aug 14, 2026
BarclaysAnalyst unavailable$329$246.23 +37.6%Aug 14, 2026
JefferiesKelly Shi$333$246.23 +39.2%Aug 13, 2026
Morgan StanleyAnalyst unavailable$275$253.6 +15.0%Jul 23, 2026
RBC CapitalAnalyst unavailable$280$267.92 +17.1%Jul 7, 2026
Evercore ISIAnalyst unavailable$329$241.83 +37.6%May 15, 2026
BarclaysAnalyst unavailable$345$238.66 +44.2%May 11, 2026
Wells FargoAnalyst unavailable$326$246.14 +36.3%May 8, 2026
JefferiesAnalyst unavailable$262$237.35 +9.5%Mar 5, 2026
Stifel NicolausAlex Thompson$332$241.38 +38.8%Mar 4, 2026
Wolfe ResearchKalpit Patel$260$231.46 +8.7%Mar 2, 2026
Cantor FitzgeraldLi Watsek$300$231.43 +25.4%Mar 2, 2026
Evercore ISIJosh Schimmer$324$234.07 +35.5%Mar 2, 2026
Goldman SachsPaul Choi$255$233.5 +6.6%Mar 2, 2026
WedbushAnalyst unavailable$273$218.39 +14.1%Feb 12, 2026
OppenheimerAnalyst unavailable$262$217.93 +9.5%Feb 12, 2026
Stifel NicolausAlex Thompson$325$218.04 +35.9%Feb 12, 2026
Morgan StanleyMaxwell Skor$256$221.49 +7.0%Feb 12, 2026
BarclaysEliana Merle$342$238.8 +43.0%Jan 27, 2026
RBC CapitalAnalyst unavailable$250$205.83 +4.5%Jan 20, 2026
Wells FargoDerek Archila$330$205.83 +38.0%Jan 20, 2026
Wells FargoAnalyst unavailable$322$208.75 +34.6%Jan 9, 2026
Stifel NicolausAlex Thompson$256$201.37 +7.0%Dec 11, 2025
Cantor FitzgeraldLi Watsek$254$209.55 +6.2%Oct 13, 2025
RBC CapitalLuca Issi$230$191.49 -3.8%Aug 8, 2025
Morgan StanleyAnalyst unavailable$180$144.08 -24.7%Feb 18, 2025
Bank of America SecuritiesTazeen Ahmad$191$151.26 -20.1%Sep 23, 2024
Evercore ISIGavin Clark-Gartner$205$144.97 -14.3%Sep 17, 2024
OppenheimerLeland Gershell$190$143.9 -20.6%Sep 17, 2024
CitigroupDavid Lebowitz$207$139.57 -13.5%Sep 17, 2024
Wells FargoDerek Archila$289$139.57 +20.8%Sep 17, 2024
Bank of America SecuritiesTazeen Ahmad$175$142.26 -26.8%Sep 16, 2024
Goldman SachsPaul Choi$200$142.26 -16.4%Sep 16, 2024
CitigroupDavid Lebowitz$178$118 -25.6%Sep 13, 2024
OppenheimerLeland Gershell$180$122.4 -24.7%Sep 5, 2024
JefferiesKelly Shi$196$128.48 -18.1%Aug 13, 2024
Stifel NicolausAlex Thompson$200$137.45 -16.4%May 30, 2024
Morgan StanleyVikram Purohit$140$124.04 -41.5%May 15, 2024
Evercore ISIJosh Schimmer$191$149.89 -20.1%Mar 14, 2024
Wells FargoAnalyst unavailable$177$118.87 -26.0%Jan 3, 2023
Morgan StanleyAnalyst unavailable$148$111.47 -38.1%Nov 15, 2022
Leerink PartnersAnalyst unavailable$148$110.26 -38.1%Nov 14, 2022
WedbushAnalyst unavailable$164$110.26 -31.4%Nov 14, 2022
Bank of America SecuritiesTazeen Ahmad$161$117.44 -32.7%Mar 20, 2022
CitigroupDavid Lebovitz$187$112.39 -21.8%Feb 28, 2022
Cowen & Co.Yaron Werber$136$121.7 -43.1%Jan 6, 2022
Canaccord GenuityMichelle Gilson$196$126.68 -18.1%Jul 7, 2021
Cantor FitzgeraldAlethia Young$201$134.4 -16.0%Jun 14, 2021
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Company context

Snapshot as of publication

Ascendis Pharma A/S is a biopharmaceutical enterprise dedicated to advancing therapeutic solutions for critical medical conditions that currently lack effective treatments. Its commercialized offering is SKYTROFA, a therapy prescribed for individuals suffering from growth hormone deficiency (GHD). The company boasts a robust development pipeline, featuring several TransCon-branded candidates. These include TransCon Growth Hormone (hGH), which is being progressed for pediatric GHD patients in Japan and for adults with GHD. Also under development are TransCon parathyroid hormone for adults with hypoparathyroidism, and TransCon CNP, aimed at treating pediatric achondroplasia. Further expanding its innovative portfolio, Ascendis is also developing a TransCon toll-like receptor (TLR) 7/8 agonist for intratumoral administration, alongside TransCon IL-2 ß/g, designed for systemic delivery. Founded in 2006, this enterprise maintains its corporate headquarters in Hellerup, Denmark.

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Sources

  1. Earnings call transcript and parsed analysis · 2026-08-13T21:19:22.021954+00:00
  2. FN2 earnings calendar · 2026-09-18T01:23:15.369793+00:00
  3. Polygon adjusted daily market bars · 2026-09-21T15:10:51.541073+00:00
  4. Financial Modeling Prep analyst price-target consensus and quote snapshot · 2026-09-21T15:10:51.538819+00:00

Methodology

Reported and consensus figures come from FN2's earnings event records. Market reaction and volume are calculated from daily adjusted bars around the event; abnormal move subtracts the SPY move over the same window.

Analyst target low, average, and high values are derived at request time from each named analyst's latest persisted FMP target. The current-price marker comes from FN2's persisted market snapshot. They are sell-side estimates, not an FN2 valuation or recommendation.

Transcript intelligence is a structured synthesis of the current and prior earnings-call analyses. Missing values stay missing and are never estimated.

By FN2 Research · Updated . For educational purposes only; not investment advice.